Protein: HASP
Serine/threonine-protein kinase haspin (EC 2.7.11.1) (Germ cell-specific gene 2 protein) (H-haspin) (Haploid germ cell-specific nuclear protein kinase)

Gene: HASP, HASPIN
Organism: Homo sapiens
Interactions: 128
UniProt ID: Q8TF76

Gene Ontology (top 5):
GO:0000278 - mitotic cell cycle
GO:0004672 - protein kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1353786

RBM4B
RNA-binding protein 4B

3

0

High-throughput

0.638

High

422706

A4
Amyloid-beta precursor protein

2

1

High-throughput

0.628

High

714924

EF1D
Elongation factor 1-delta

2

0

High-throughput

0.602

High

1133378

ZN169
Zinc finger protein 169

2

0

High-throughput

0.602

High

1230884

Z324B
Zinc finger protein 324B

2

0

High-throughput

0.602

High

643949

FBRL
rRNA 2'-O-methyltransferase fibrillarin

2

0

High-throughput

0.585

High

1329764

SIR6
NAD-dependent protein deacylase sirtuin-6

2

0

High-throughput

0.585

High

269316

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.580

High

1353785

MDFI
MyoD family inhibitor

2

0

High-throughput

0.580

High

920142

PLK1
Serine/threonine-protein kinase PLK1

1

1

Small-scale

0.561

High

1353793

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

1

3

Small-scale

0.552

High

998582

H31
Histone H3.1

1

3

Small-scale

0.536

High

74557

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

1

High-throughput

0.536

High

123782

MYO1C
Unconventional myosin-Ic

1

2

High-throughput

0.536

High

186774

P73
Tumor protein p73

1

1

High-throughput

0.536

High

217493

E41L2
Band 4.1-like protein 2

1

1

High-throughput

0.536

High

224755

ACTN4
Alpha-actinin-4

1

2

High-throughput

0.536

High

227930

MYO1B
Unconventional myosin-Ib

1

3

High-throughput

0.536

High

299313

FLOT1
Flotillin-1

1

1

High-throughput

0.536

High

318367

MYO1D
Unconventional myosin-Id

1

2

High-throughput

0.536

High

336460

SVIL
Supervillin

1

1

High-throughput

0.536

High

414285

P53
Cellular tumor antigen p53

1

1

High-throughput

0.536

High

418712

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

4

High-throughput

0.536

High

440647

FYN
Tyrosine-protein kinase Fyn

1

2

High-throughput

0.536

High

463175

YES
Tyrosine-protein kinase Yes

1

2

High-throughput

0.536

High

463671

LYN
Tyrosine-protein kinase Lyn

1

2

High-throughput

0.536

High

476005

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

4

High-throughput

0.536

High

983538

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

1

High-throughput

0.536

High

984214

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

1

High-throughput

0.536

High

989858

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

1

4

High-throughput

0.536

High

1006924

KC1G2
Casein kinase I isoform gamma-2

1

2

High-throughput

0.536

High

1028826

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

3

High-throughput

0.536

High

1257200

ANKS3
Ankyrin repeat and SAM domain-containing protein 3

1

1

High-throughput

0.536

High

1353783

NEB2
Neurabin-2

1

1

High-throughput

0.536

High

1353784

CEP89
Centrosomal protein of 89 kDa

1

2

High-throughput

0.536

High

1353790

KC1G1
Casein kinase I isoform gamma-1

1

2

High-throughput

0.536

High

1353791

WDR6
tRNA

1

1

High-throughput

0.536

High

1353801

NEB1
Neurabin-1

1

1

High-throughput

0.536

High

1353806

KC1G3
Casein kinase I isoform gamma-3

1

2

High-throughput

0.536

High

1353807

SCIN
Scinderin

1

1

High-throughput

0.536

High

171286

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

0

High-throughput

0.513

High

253664

IMA7
Importin subunit alpha-7

1

0

High-throughput

0.513

High

291685

XRP2
Protein XRP2

1

0

High-throughput

0.513

High

292464

PALM
Paralemmin-1

1

0

High-throughput

0.513

High

323500

TRI37
E3 ubiquitin-protein ligase TRIM37

1

0

High-throughput

0.513

High

324019

CSTN1
Calsyntenin-1

1

0

High-throughput

0.513

High

372669

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.513

High

669952

MCM3
DNA replication licensing factor MCM3

1

0

High-throughput

0.513

High

773234

MYH10
Myosin-10

1

0

High-throughput

0.513

High

774094

ADDA
Alpha-adducin

1

0

High-throughput

0.513

High

846396

MATR3
Matrin-3

1

0

High-throughput

0.513

High

854183

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

859919

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.513

High

878333

MRP
MARCKS-related protein

1

0

High-throughput

0.513

High

897161

TUB
Tubby protein homolog

1

0

High-throughput

0.513

High

988555

RAC1
Ras-related C3 botulinum toxin substrate 1

1

0

High-throughput

0.513

High

1010334

BASP1
Brain acid soluble protein 1

1

0

High-throughput

0.513

High

1055947

RAD51
DNA repair protein RAD51 homolog 1

1

0

High-throughput

0.513

High

1068268

AHNK
Neuroblast differentiation-associated protein AHNAK

1

0

High-throughput

0.513

High

1107960

SQSTM
Sequestosome-1

1

0

High-throughput

0.513

High

1120779

DSG2
Desmoglein-2

1

0

High-throughput

0.513

High

1160698

DREB
Drebrin

1

0

High-throughput

0.513

High

1178855

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.513

High

1243830

CTR9
RNA polymerase-associated protein CTR9 homolog

1

0

High-throughput

0.513

High

1245589

ZN773
Zinc finger protein 773

1

0

High-throughput

0.513

High

1260384

H1FNT
Testis-specific H1 histone

1

0

High-throughput

0.513

High

1274035

PHF5A
PHD finger-like domain-containing protein 5A

1

0

High-throughput

0.513

High

1308687

FMNL3
Formin-like protein 3

1

0

High-throughput

0.513

High

1353778

ARK2N
Protein ARK2N

1

0

High-throughput

0.513

High

1353779

THA11
THAP domain-containing protein 11

1

0

High-throughput

0.513

High

1353782

MAGD4
Melanoma-associated antigen D4

1

0

High-throughput

0.513

High

1353788

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

0

High-throughput

0.513

High

1353794

NSE4A
Non-structural maintenance of chromosomes element 4 homolog A

1

0

High-throughput

0.513

High

1353799

HERC5
E3 ISG15--protein ligase HERC5

1

0

High-throughput

0.513

High

1353805

NGN3
Neurogenin-3

1

0

High-throughput

0.513

High

468641

HS90B
Heat shock protein HSP 90-beta

1

0

High-throughput

0.493

High

174784

SPTN2
Spectrin beta chain, non-erythrocytic 2

1

3

High-throughput

0.489

High

207856

ZZEF1
Zinc finger ZZ-type and EF-hand domain-containing protein 1

1

1

High-throughput

0.489

High

539831

RALA
Ras-related protein Ral-A

1

1

High-throughput

0.489

High

967222

RRAS2
Ras-related protein R-Ras2

1

1

High-throughput

0.489

High

1117419

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

3

High-throughput

0.489

High

1124873

FLOT2
Flotillin-2

1

1

High-throughput

0.489

High

1212595

HECD3
E3 ubiquitin-protein ligase HECTD3

1

1

High-throughput

0.489

High

1250742

MPRIP
Myosin phosphatase Rho-interacting protein

1

1

High-throughput

0.489

High

1353803

E41L3
Band 4.1-like protein 3

1

1

High-throughput

0.489

High

443457

CDK1
Cyclin-dependent kinase 1

1

0

Small-scale

0.480

High

1353781

AURKB
Aurora kinase B

1

0

Small-scale

0.480

High

989763

GNAS2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

1

5

High-throughput

0.479

High

1155578

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.479

High

1177608

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

3

Small-scale

0.479

High

123270

PDLI1
PDZ and LIM domain protein 1

1

0

High-throughput

0.458

High

157655

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

223207

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

260205

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

504938

H2AB2
Histone H2A-Bbd type 2/3

1

0

High-throughput

0.458

High

1028302

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.458

High

1029117

E2F1
Transcription factor E2F1

1

0

Small-scale

0.458

High

1045563

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1353789

NANOG
Homeobox protein NANOG

1

0

High-throughput

0.458

High

1353798

XPO7
Exportin-7

1

0

High-throughput

0.458

High

1207503

GNAS1
Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

1

5

High-throughput

0.445

High

404853

PRIO
Major prion protein

1

0

High-throughput

0.426

High

1198608

NCBP3
Nuclear cap-binding protein subunit 3

1

0

High-throughput

0.426

High

888473

TSP3
Thrombospondin-3

2

0

High-throughput

0.328

High

1060895

LRP1
Prolow-density lipoprotein receptor-related protein 1

2

0

High-throughput

0.328

High

1278547

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

2

0

High-throughput

0.328

High

1353792

TNR19
Tumor necrosis factor receptor superfamily member 19

2

0

High-throughput

0.328

High

1353800

PNMA2
Paraneoplastic antigen Ma2

2

0

High-throughput

0.328

High

270380

WDR1
WD repeat-containing protein 1

1

0

High-throughput

0.279

Low

399602

VTNC
Vitronectin

1

0

High-throughput

0.279

Low

569204

CD59
CD59 glycoprotein

1

0

High-throughput

0.279

Low

706235

S10A2
Protein S100-A2

1

0

High-throughput

0.279

Low

829477

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

0

High-throughput

0.279

Low

867293

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.279

Low

915140

CAZA1
F-actin-capping protein subunit alpha-1

1

0

High-throughput

0.279

Low

928799

CA2D1
Voltage-dependent calcium channel subunit alpha-2/delta-1

1

0

High-throughput

0.279

Low

1088158

CNTN1
Contactin-1

1

0

High-throughput

0.279

Low

1248276

MOXD1
DBH-like monooxygenase protein 1

1

0

High-throughput

0.279

Low

1327095

FBXL6
F-box/LRR-repeat protein 6

1

0

High-throughput

0.279

Low

1353777

ASM3B
Acid sphingomyelinase-like phosphodiesterase 3b

1

0

High-throughput

0.279

Low

1353780

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.279

Low

1353787

GAPR1
Golgi-associated plant pathogenesis-related protein 1

1

0

High-throughput

0.279

Low

1353795

TMOD3
Tropomodulin-3

1

0

High-throughput

0.279

Low

1353796

GBG12

1

0

High-throughput

0.279

Low

1353797

LIMA1
LIM domain and actin-binding protein 1

1

0

High-throughput

0.279

Low

1353802

COR1C
Coronin-1C

1

0

High-throughput

0.279

Low

1353804

TDRKH
Tudor and KH domain-containing protein

1

0

High-throughput

0.279

Low

106343

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025