HitPredict

Interactor 1: EHMT1 (Q5DW34)
Histone-lysine N-methyltransferase EHMT1 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a-like protein 1) (GLP) (GLP1) (Lysine N-methyltransferase 1D)
Gene: EHMT1

Interactor 2: Q9DCC5 (Q9DCC5)
Cbx3 protein (Chromobox 3)
Gene: Cbx3

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29795351
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1296 Mm			1 183
+	Mm
		949933 EHMT1_MOUSE (1-1296): 0: 1013: 100.00		CBX1_MOUSE (36-180): 1.02e-53: 170: 71.33
+	Hs
		1027268 EHMT1_HUMAN (13-1296): 0: 954: 88.67		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		800530 EHMT1_HUMAN (13-1296): 0: 954: 88.67		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		949889 EHMT1_HUMAN (13-1296): 0: 954: 88.67		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Hs
		1331975 EHMT1_HUMAN (13-1296): 0: 954: 88.67		SUV92_HUMAN (6-156): 4.05e-43: 149: 25.15
+	Hs
		203794 EHMT1_HUMAN (13-1296): 0: 954: 88.67		SUV91_HUMAN (3-179): 4.73e-40: 141: 16.20
+	Hs
		1334148 EHMT1_HUMAN (13-1296): 0: 954: 88.67		CDY2_HUMAN (27-124): 2.81e-26: 106: 28.16
+	Mm
		1322180 EHMT2_MOUSE (119-1289): 0: 699: 45.72		Q9DCC5_MOUSE (1-183): 1.62e-71: 215: 100.00
+	Hs
		1027194 EHMT2_HUMAN (133-1289): 0: 679: 45.97		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Mm
		1143050 EHMT2_MOUSE (119-1289): 0: 699: 45.72		CBX5_MOUSE (11-182): 1.21e-55: 175: 59.89
+	Mm
		949963 EHMT2_MOUSE (119-1289): 0: 699: 45.72		CBX1_MOUSE (36-180): 1.02e-53: 170: 71.33
+	Hs
		800497 EHMT2_HUMAN (133-1289): 0: 679: 45.97		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		949863 EHMT2_HUMAN (133-1289): 0: 679: 45.97		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Mm
		1376692 EHMT2_MOUSE (119-1289): 0: 699: 45.72		CDYL_MOUSE (16-165): 1.82e-36: 134: 25.16
+	Hs
		1296419 EHMT2_HUMAN (133-1289): 0: 679: 45.97		SUV92_HUMAN (6-156): 4.05e-43: 149: 25.15
+	Hs
		203766 EHMT2_HUMAN (133-1289): 0: 679: 45.97		SUV91_HUMAN (3-179): 4.73e-40: 141: 16.20
+	Hs
		1296443 EHMT2_HUMAN (133-1289): 0: 679: 45.97		CDYL_HUMAN (16-165): 6.53e-34: 127: 25.16
+	Mm
		1112138 EHMT2_MOUSE (119-1289): 0: 699: 45.72		MPP8_MOUSE (5-115): 6.16e-25: 102: 27.68
+	Hs
		1296450 EHMT2_HUMAN (133-1289): 0: 679: 45.97		CDY2_HUMAN (27-124): 2.81e-26: 106: 28.16
+	Dm
		115785 M9PGH7_DROME (7-1289): 5.58e-128: 434: 20.35		HP1_DROME (9-180): 2.12e-45: 150: 38.73