Interactor 1: BECN1 (Q14457)
Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197) [Cleaved into: Beclin-1-C 35 kDa; Beclin-1-C 37 kDa]
Gene: BECN1

Interactor 2: UVRAG (Q9P2Y5)
UV radiation resistance-associated gene protein (p63)
Gene: UVRAG

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.994

The method score is based on:

Property Details
Experiments 18641390, 18843052, 19050071, 23878393, 26496610, 30258449, 24956373, 22314358, 27621469, 24879154, 32296183, 19372752, 19270693, 31373534, 33977871, 23954414, 35271311, 34386498, 40437099, 20562859 and 15 others

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Identification Methods pull down, affinity chromatography technology, two hybrid, biochemical, cross-linking study, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, tandem affinity purification, isothermal titration calorimetry, two hybrid array and 2 others

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Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains APG6~ATG14, APG6_N~ATG14
Common GO terms GO:0005737 - cytoplasm
GO:0005768 - endosome
GO:0005783 - endoplasmic reticulum
GO:0006914 - autophagy
GO:0010506 - regulation of autophagy
and 6 others

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Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 450
Hs

1 699
+ Mm
+ Hs
+ Sp
+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025