HitPredict

Interactor 1: MTUS2 (Q5JR59)
Microtubule-associated tumor suppressor candidate 2 (Cardiac zipper protein) (Microtubule plus-end tracking protein TIP150) (Tracking protein of 150 kDa)
Gene: MTUS2

Interactor 2: LIMS2 (Q7Z4I7)
LIM and senescent cell antigen-like-containing domain protein 2 (LIM-like protein 2) (Particularly interesting new Cys-His protein 2) (PINCH-2)
Gene: LIMS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.573

Property	Details
Experiments	25416956
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1369 Hs			1 341
+	Hs
		549176 MTUS2_HUMAN (1-1369): 0: 1143: 100.00		ZN250_HUMAN (1-279): 4.73e-73: 237: 11.51
+	Hs
		200826 MTUS2_HUMAN (1-1369): 0: 1143: 100.00		ZSC12_HUMAN (128-337): 2.26e-51: 181: 12.61
+	Hs
		1127192 MTUS2_HUMAN (1-1369): 0: 1143: 100.00		ZN624_HUMAN (1-194): 1.1e-44: 165: 12.90
+	Hs
		1127017 MTUS2_HUMAN (1-1369): 0: 1143: 100.00		ZFP2_HUMAN (161-336): 3.18e-36: 138: 10.75
+	Hs
		532313 MTUS2_HUMAN (1-1369): 0: 1143: 100.00		ZNF35_HUMAN (251-337): 2.57e-19: 90.7: 11.58
+	Hs
		1044605 MTUS2_HUMAN (1-1369): 0: 1143: 100.00		FHL3_HUMAN (222-340): 7.54e-15: 75.4: 21.49
+	Hs
		823386 ROCK1_HUMAN (672-1362): 3.23e-31: 135: 11.70		PAXI_HUMAN (6-131): 1.64e-36: 140: 29.37
+	Hs
		200805 DESP_HUMAN (972-1329): 6.4e-13: 76: 15.94		ZSC12_HUMAN (128-337): 2.26e-51: 181: 12.61
+	Hs
		522595 MYH7_HUMAN (1006-1369): 1.13e-19: 98.4: 14.56		LIMS1_HUMAN (3-251): 1.22e-43: 154: 25.39
+	Hs
		816296 MYH4_HUMAN (698-1170): 2e-13: 77.9: 8.56		LIMS1_HUMAN (3-251): 1.22e-43: 154: 25.39
+	Hs
		823446 NIN_HUMAN (992-1353): 2.45e-14: 80.6: 18.36		PAXI_HUMAN (6-131): 1.64e-36: 140: 29.37
+	Hs
		150533 MYH9_HUMAN (683-1130): 6.12e-12: 72.9: 9.70		ABLM1_HUMAN (3-151): 2.72e-26: 111: 22.15
+	Hs
		1050845 MTUS1_HUMAN (600-1071): 1.41e-12: 74.9: 7.72		FHL2_HUMAN (222-340): 9.42e-16: 78.1: 24.79
+	Hs
		1044734 MTUS1_HUMAN (600-1071): 1.41e-12: 74.9: 7.72		FHL3_HUMAN (222-340): 7.54e-15: 75.4: 21.49
+	Hs
		1343899 MYO5C_HUMAN (989-1334): 1.01e-13: 78.7: 19.18		PDLI7_HUMAN (14-169): 5.97e-13: 71.2: 29.11
+	Hs
		725036 MYH9_HUMAN (683-1130): 6.12e-12: 72.9: 9.70		PDLI7_HUMAN (14-169): 5.97e-13: 71.2: 29.11