Interactor 1: DHX8 (Q14562)
ATP-dependent RNA helicase DHX8 (EC 3.6.4.13) (DEAH box protein 8) (RNA helicase HRH1)
Gene: DHX8

Interactor 2: GPTC1 (Q9BRR8)
G patch domain-containing protein 1 (Evolutionarily conserved G-patch domain-containing protein)
Gene: GPATCH1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 34079125, unassigned3799
Identification Methods proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains G-patch~HA2_N, G-patch~Helicase_C, DUF1604~OB_NTP_bind, G-patch~OB_NTP_bind
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0071013 - catalytic step 2 spliceosome
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1220
Hs

1 931
+ Hs
+ Sp
+ Dm
+ Hs

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Last updated: 11Aug2025