Interactor 1: IHH (Q14623)
Indian hedgehog protein (IHH) (EC 3.1.-.-) (HHG-2) [Cleaved into: Indian hedgehog protein N-product]
Gene: IHH
Interactor 2: CDON (Q4KMG0)
Cell adhesion molecule-related/down-regulated by oncogenes
Gene: CDON
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 20519495 |
| Identification Methods | x-ray crystallography |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | HH_signal~fn3 |
| Common GO terms | GO:0001708 - cell fate specification GO:0005886 - plasma membrane GO:0007224 - smoothened signaling pathway GO:0045944 - positive regulation of transcription by RNA polymerase II |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
