Protein: DHH
Desert hedgehog protein (DHH) (EC 3.1.-.-) (HHG-3) [Cleaved into: Desert hedgehog protein N-product (DHH-N)]

Gene: DHH
Organism: Homo sapiens
Interactions: 43
UniProt ID: O43323

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0001649 - osteoblast differentiation
GO:0001708 - cell fate specification
GO:0005113 - patched binding
GO:0005509 - calcium ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

214141

HHIP
Hedgehog-interacting protein

2

4

Small-scale

0.811

High

214125

CDON
Cell adhesion molecule-related/down-regulated by oncogenes

1

5

Small-scale

0.692

High

214143

BOC
Brother of CDO

1

5

Small-scale

0.692

High

214115

BIP
Endoplasmic reticulum chaperone BiP

2

0

High-throughput

0.602

High

214144

FKB14
Peptidyl-prolyl cis-trans isomerase FKBP14

2

0

High-throughput

0.602

High

214110

SEMG1
Semenogelin-1

1

1

High-throughput

0.536

High

214121

SEMG2
Semenogelin-2

1

1

High-throughput

0.536

High

136574

MANBA
Beta-mannosidase

1

0

High-throughput

0.513

High

214108

LRP6
Low-density lipoprotein receptor-related protein 6

1

0

High-throughput

0.513

High

214109

CLPT1
Putative lipid scramblase CLPTM1

1

0

High-throughput

0.513

High

214111

IPSP
Plasma serine protease inhibitor

1

0

High-throughput

0.513

High

214112

ITAV
Integrin alpha-V

1

0

High-throughput

0.513

High

214113

KLK3
Prostate-specific antigen

1

0

High-throughput

0.513

High

214116

PPAP
Prostatic acid phosphatase

1

0

High-throughput

0.513

High

214120

MA2A2
Alpha-mannosidase 2x

1

0

High-throughput

0.513

High

214122

GALT1
Polypeptide N-acetylgalactosaminyltransferase 1

1

0

High-throughput

0.513

High

214123

HYAL2
Hyaluronidase-2

1

0

High-throughput

0.513

High

214127

GT253
Inactive glycosyltransferase 25 family member 3

1

0

High-throughput

0.513

High

214131

PMGT2
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.513

High

214133

CHSTE
Carbohydrate sulfotransferase 14

1

0

High-throughput

0.513

High

214137

EXT2
Exostosin-2

1

0

High-throughput

0.513

High

214138

TTC17
Tetratricopeptide repeat protein 17

1

0

High-throughput

0.513

High

214142

PMYT1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

1

0

High-throughput

0.513

High

214145

SELN
Selenoprotein N

1

0

High-throughput

0.513

High

214129

SE1L3
Protein sel-1 homolog 3

1

1

High-throughput

0.489

High

214130

P3H3
Prolyl 3-hydroxylase 3

1

1

High-throughput

0.489

High

214136

SC65
Endoplasmic reticulum protein SC65

1

1

High-throughput

0.489

High

214119

RPIA
Ribose-5-phosphate isomerase

2

0

High-throughput

0.328

High

214126

EIPR1
EARP and GARP complex-interacting protein 1

2

0

High-throughput

0.328

High

214139

RCC1L
RCC1-like G exchanging factor-like protein

2

0

High-throughput

0.328

High

214106

SNX3
Sorting nexin-3

1

0

High-throughput

0.279

Low

214107

NDK6
Nucleoside diphosphate kinase 6

1

0

High-throughput

0.279

Low

214114

PAEP
Glycodelin

1

0

High-throughput

0.279

Low

214117

NMU
Neuromedin-U [Cleaved into: Neuromedin precursor-related peptide 36

1

0

High-throughput

0.279

Low

214118

TGM4
Protein-glutamine gamma-glutamyltransferase 4

1

0

High-throughput

0.279

Low

214124

LAMB3
Laminin subunit beta-3

1

0

High-throughput

0.279

Low

214128

GL8D1
Glycosyltransferase 8 domain-containing protein 1

1

0

High-throughput

0.279

Low

214132

PGLT1
Protein O-glucosyltransferase 1

1

0

High-throughput

0.279

Low

214134

GPX8
Probable glutathione peroxidase 8

1

0

High-throughput

0.279

Low

214135

TM131
Transmembrane protein 131

1

0

High-throughput

0.279

Low

214140

VPS50
Syndetin

1

0

High-throughput

0.279

Low

214146

SUN2
SUN domain-containing protein 2

1

0

High-throughput

0.279

Low

214147

VPS51
Vacuolar protein sorting-associated protein 51 homolog

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025