HitPredict

Interactor 1: PUM1 (Q14671)
Pumilio homolog 1 (HsPUM) (Pumilio-1)
Gene: PUM1

Interactor 2: IF2B2 (Q9Y6M1)
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62) (IGF-II mRNA-binding protein 2) (VICKZ family member 2)
Gene: IGF2BP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000932 - P-body GO:0003723 - RNA binding GO:0003730 - mRNA 3'-UTR binding GO:0005737 - cytoplasm GO:0005829 - cytosol and 1 others more... GO:0010494 - cytoplasmic stress granule
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1186 Hs			1 599
+	Hs
		135212 PUM1_HUMAN (1-1186): 0: 1497: 100.00		IF2B3_HUMAN (2-599): 4.98e-140: 420: 62.19
+	Hs
		1129524 PUM1_HUMAN (1-1186): 0: 1497: 100.00		IF2B1_HUMAN (2-599): 6.45e-136: 410: 63.89
+	Hs
		550286 PUM1_HUMAN (1-1186): 0: 1497: 100.00		PABP1_HUMAN (2-444): 5.64e-43: 165: 14.58
+	Hs
		1348149 PUM2_HUMAN (128-1186): 0: 1176: 76.67		IF2B2_HUMAN (1-599): 1.75e-152: 453: 100.00
+	Hs
		1129481 PUM1_HUMAN (1-1186): 0: 1497: 100.00		FUBP3_HUMAN (181-429): 2.9e-23: 106: 14.82
+	Hs
		550371 PUM2_HUMAN (128-1186): 0: 1176: 76.67		PABP1_HUMAN (2-444): 5.64e-43: 165: 14.58
+	Hs
		1348111 PUM2_HUMAN (128-1186): 0: 1176: 76.67		FUBP3_HUMAN (181-429): 2.9e-23: 106: 14.82
+	Mm
		966039 PUM3_MOUSE (698-1175): 1.01e-89: 305: 16.16		HNRPK_MOUSE (390-596): 9.53e-21: 97.3: 17.83