HitPredict

Interactor 1: MDC1 (Q14676)
Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1)
Gene: MDC1

Interactor 2: APC1 (Q9H1A4)
Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein)
Gene: ANAPC1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 0.60 0.646

The method score is based on:

Property Details
Experiments 19826003, 17827148, 22990118
Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 2089
Hs

1 1944
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025