Interactor 1: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Interactor 2: BAG5 (Q9UL15)
BAG family molecular chaperone regulator 5 (BAG-5) (Bcl-2-associated athanogene 5)
Gene: BAG5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 0.60 0.677

The method score is based on:

Property Details
Experiments 24510904, 19001729, 24947832
Identification Methods affinity chromatography technology, pull down, two hybrid, protein array, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0007030 - Golgi organization
GO:0010977 - negative regulation of neuron projection development
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 2527
Hs

1 447
+ Mm
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024