HitPredict

Interactor 1: CAF17 (Q5T440)
Putative transferase CAF17, mitochondrial (EC 2.1.-.-) (Iron-sulfur cluster assembly factor homolog)
Gene: IBA57

Interactor 2: ISCA2 (Q86U28)
Iron-sulfur cluster assembly 2 homolog, mitochondrial (HESB-like domain-containing protein 1)
Gene: ISCA2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.629

Property	Details
Experiments	33961781, 31831856
Identification Methods	affinity chromatography technology, x ray scattering, molecular sieving, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005759 - mitochondrial matrix GO:0016226 - iron-sulfur cluster assembly
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 356 Hs			1 154
+	Hs
		1133188 CAF17_HUMAN (1-356): 7.74e-168: 473: 100.00		ISCA1_HUMAN (26-152): 8.09e-49: 155: 25.39
+	Ss
		937177 Q55712_SYNY3 (50-348): 6.17e-92: 279: 21.22		Y1417_SYNY3 (39-152): 1.45e-41: 136: 32.77
+	Sc
		812522 CAF17_YEAST (53-351): 2.62e-82: 260: 22.65		ISA1_YEAST (50-152): 7.84e-43: 144: 29.52
+	Sc
		812523 CAF17_YEAST (53-351): 2.62e-82: 260: 22.65		ISA2_YEAST (45-153): 1.57e-34: 120: 30.30
+	Ec
		467044 YGFZ_ECOLI (38-280): 7.07e-74: 233: 21.79		ERPA_ECOLI (50-152): 5.62e-40: 132: 38.32