Protein: TIA1
Cytotoxic granule associated RNA binding protein TIA1 (Nucleolysin TIA-1) (RNA-binding protein TIA-1) (T-cell-restricted intracellular antigen-1) (TIA-1)

Gene: TIA1
Organism: Mus musculus
Interactions: 169
UniProt ID: P52912

Gene Ontology (top 5):
GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0001818 - negative regulation of cytokine production
GO:0003730 - mRNA 3'-UTR binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

205516

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

14

Small-scale

0.618

High

424702

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

8

High-throughput

0.618

High

570735

RL7
Large ribosomal subunit protein uL30

1

5

High-throughput

0.618

High

591024

KPCE
Protein kinase C epsilon type

1

4

High-throughput

0.618

High

685791

U2AF2
Splicing factor U2AF 65 kDa subunit

1

17

High-throughput

0.618

High

710979

PABP1
Polyadenylate-binding protein 1

1

14

High-throughput

0.618

High

728901

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

1

6

High-throughput

0.618

High

915276

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.618

High

915277

TRA2B
Transformer-2 protein homolog beta

1

17

High-throughput

0.618

High

915278

MK01
Mitogen-activated protein kinase 1

1

7

High-throughput

0.618

High

915280

KPCG
Protein kinase C gamma type

1

6

High-throughput

0.618

High

915282

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

7

High-throughput

0.618

High

915283

KPCB
Protein kinase C beta type

1

5

High-throughput

0.618

High

915284

ELAV1
ELAV-like protein 1

1

17

Small-scale

0.618

High

915295

Q3UZI0
Heterogeneous nuclear ribonucleoprotein Q

1

17

High-throughput

0.618

High

915302

EWS
RNA-binding protein EWS

1

6

High-throughput

0.618

High

915306

SRSF2
Serine/arginine-rich splicing factor 2

1

17

High-throughput

0.618

High

915308

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

16

High-throughput

0.618

High

915313

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

12

High-throughput

0.618

High

915314

SRSF1
Serine/arginine-rich splicing factor 1

1

17

Small-scale

0.618

High

915317

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

17

High-throughput

0.618

High

915328

SPF45
Splicing factor 45

1

7

High-throughput

0.618

High

915333

PSPC1
Paraspeckle component 1

1

19

High-throughput

0.618

High

915342

TADBP
TAR DNA-binding protein 43

1

17

Small-scale

0.618

High

915373

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

15

High-throughput

0.618

High

757444

FAK1
Focal adhesion kinase 1

2

4

Small-scale

0.584

High

530733

TAU
Microtubule-associated protein tau

1

9

High-throughput

0.561

High

697716

PDIA3
Protein disulfide-isomerase A3

1

1

High-throughput

0.553

High

915292

CAMKV
CaM kinase-like vesicle-associated protein

1

1

High-throughput

0.553

High

915298

Q542V3
Serine and arginine-rich splicing factor 4

1

17

High-throughput

0.553

High

63095

A5D6Q2
Nuclear receptor coactivator 3

1

1

Small-scale

0.479

High

148160

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

204272

PHB2
Prohibitin-2

1

5

High-throughput

0.479

High

266658

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

1

2

High-throughput

0.479

High

266871

E41L2
Band 4.1-like protein 2

1

2

High-throughput

0.479

High

312865

CTBP1
C-terminal-binding protein 1

1

2

High-throughput

0.479

High

508984

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

1

8

High-throughput

0.479

High

531205

GSTM1
Glutathione S-transferase Mu 1

1

2

High-throughput

0.479

High

570771

MDHC
Malate dehydrogenase, cytoplasmic

1

2

High-throughput

0.479

High

618928

GSTP1
Glutathione S-transferase P 1

1

1

High-throughput

0.479

High

619292

RL13A
Large ribosomal subunit protein uL13

1

3

High-throughput

0.479

High

690152

RSMB
Small nuclear ribonucleoprotein-associated protein B

1

3

High-throughput

0.479

High

704308

SEPT4
Septin-4

1

2

High-throughput

0.479

High

732012

GTR3
Solute carrier family 2, facilitated glucose transporter member 3

1

1

High-throughput

0.479

High

801606

HSPA9
Stress-70 protein, mitochondrial

1

5

High-throughput

0.479

High

840614

PURA
Transcriptional activator protein Pur-alpha

1

2

High-throughput

0.479

High

846983

H14
Histone H1.4

1

4

High-throughput

0.479

High

867923

PFKAM
ATP-dependent 6-phosphofructokinase, muscle type

1

1

High-throughput

0.479

High

868406

RL6
Large ribosomal subunit protein eL6

1

3

High-throughput

0.479

High

868950

RL13
Large ribosomal subunit protein eL13

1

1

High-throughput

0.479

High

872958

SOX2
Transcription factor SOX-2

1

4

High-throughput

0.479

High

895991

VATA
V-type proton ATPase catalytic subunit A

1

2

High-throughput

0.479

High

915268

PCBP1
Poly(rC)-binding protein 1

1

17

High-throughput

0.479

High

915269

IF4A1
Eukaryotic initiation factor 4A-I

1

17

High-throughput

0.479

High

915273

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

7

High-throughput

0.479

High

915274

RS4X
Small ribosomal subunit protein eS4

1

2

High-throughput

0.479

High

915275

RAN
GTP-binding nuclear protein Ran

1

1

High-throughput

0.479

High

915279

HMGB1
High mobility group protein B1

1

8

High-throughput

0.479

High

915281

PHB1
Prohibitin 1

1

5

High-throughput

0.479

High

915285

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

1

High-throughput

0.479

High

915286

CTNB1
Catenin beta-1

1

2

High-throughput

0.479

High

915287

GRB7
Growth factor receptor-bound protein 7

1

6

Small-scale

0.479

High

915288

ANXA7
Annexin A7

1

1

High-throughput

0.479

High

915294

HDGR2
Hepatoma-derived growth factor-related protein 2

1

2

High-throughput

0.479

High

915296

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

5

High-throughput

0.479

High

915297

DDX17
Probable ATP-dependent RNA helicase DDX17

1

6

High-throughput

0.479

High

915300

NACA
Nascent polypeptide-associated complex subunit alpha

1

1

High-throughput

0.479

High

915301

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

3

High-throughput

0.479

High

915303

FSCN1
Fascin

1

1

High-throughput

0.479

High

915307

DPYL3
Dihydropyrimidinase-related protein 3

1

1

High-throughput

0.479

High

915312

CLCB
Clathrin light chain B

1

1

High-throughput

0.479

High

915315

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

3

High-throughput

0.479

High

915325

Q8BTS0
Probable ATP-dependent RNA helicase DDX5

1

8

High-throughput

0.479

High

915334

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

2

High-throughput

0.479

High

915336

RAB14
Ras-related protein Rab-14

1

1

High-throughput

0.479

High

915340

PI42C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

1

2

High-throughput

0.479

High

915344

Q99JL6
Ribosomal protein

1

1

High-throughput

0.479

High

915348

RAB5A
Ras-related protein Rab-5A

1

3

High-throughput

0.479

High

915351

SERB1
SERPINE1 mRNA-binding protein 1

1

2

High-throughput

0.479

High

915359

RM46
Large ribosomal subunit protein mL46

1

2

High-throughput

0.479

High

915360

TRIM2
Tripartite motif-containing protein 2

1

9

High-throughput

0.479

High

915361

IVD
Isovaleryl-CoA dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

915363

ADDA
Alpha-adducin

1

3

High-throughput

0.479

High

915365

HTRA1
Serine protease HTRA1

1

1

High-throughput

0.479

High

915368

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

1

High-throughput

0.479

High

915370

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

1

High-throughput

0.479

High

915374

HOME1
Homer protein homolog 1

1

5

High-throughput

0.479

High

94727

E0CYV0
Protein-L-isoaspartate O-methyltransferase

1

0

High-throughput

0.458

High

236960

CRYM
Ketimine reductase mu-crystallin

1

0

High-throughput

0.458

High

313456

LANC1
Glutathione S-transferase LANCL1

1

0

High-throughput

0.458

High

361943

HPRT
Hypoxanthine-guanine phosphoribosyltransferase

1

0

High-throughput

0.458

High

367622

CAH2
Carbonic anhydrase 2

1

0

High-throughput

0.458

High

426365

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.458

High

446489

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.458

High

559563

GELS
Gelsolin

1

0

High-throughput

0.458

High

571259

AT1B2
Sodium/potassium-transporting ATPase subunit beta-2

1

0

High-throughput

0.458

High

574828

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

0

High-throughput

0.458

High

687628

SYSC
Serine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

912285

KPYM
Pyruvate kinase PKM

1

0

High-throughput

0.458

High

915267

ACTN4
Alpha-actinin-4

1

0

High-throughput

0.458

High

915270

SNP25
Synaptosomal-associated protein 25

1

0

High-throughput

0.458

High

915289

PSA
Puromycin-sensitive aminopeptidase

1

0

High-throughput

0.458

High

915290

PHAR1
Phosphatase and actin regulator 1

1

0

High-throughput

0.458

High

915293

HAP28
28 kDa heat- and acid-stable phosphoprotein

1

0

High-throughput

0.458

High

915304

PACN1
Protein kinase C and casein kinase substrate in neurons protein 1

1

0

High-throughput

0.458

High

915311

SAHH3
Putative adenosylhomocysteinase 3

1

0

High-throughput

0.458

High

915318

TPPP
Tubulin polymerization-promoting protein

1

0

High-throughput

0.458

High

915320

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.458

High

915329

PHYIP
Phytanoyl-CoA hydroxylase-interacting protein

1

0

High-throughput

0.458

High

915330

PDXK
Pyridoxal kinase

1

0

High-throughput

0.458

High

915335

BACH
Cytosolic acyl coenzyme A thioester hydrolase

1

0

High-throughput

0.458

High

915346

NAMPT
Nicotinamide phosphoribosyltransferase

1

0

High-throughput

0.458

High

915350

CENPV
Centromere protein V

1

0

High-throughput

0.458

High

915353

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

0

High-throughput

0.458

High

915364

GUAD
Guanine deaminase

1

0

High-throughput

0.458

High

915366

PSA4
Proteasome subunit alpha type-4

1

0

High-throughput

0.458

High

73059

B1AWE1
Clathrin light chain

1

1

High-throughput

0.437

High

98277

E9QAH1
Golgin B1

1

2

High-throughput

0.437

High

104759

F7AAP4
Calcium-transporting ATPase

1

2

High-throughput

0.437

High

237159

NIPS1
Protein NipSnap homolog 1

1

1

High-throughput

0.437

High

237224

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

1

High-throughput

0.437

High

313335

COR1A
Coronin-1A

1

2

High-throughput

0.437

High

449236

TNFA
Tumor necrosis factor

1

2

Small-scale

0.437

High

469589

MDHM
Malate dehydrogenase, mitochondrial

1

1

High-throughput

0.437

High

604451

AP2A1
AP-2 complex subunit alpha-1

1

4

High-throughput

0.437

High

604476

AP2A2
AP-2 complex subunit alpha-2

1

4

High-throughput

0.437

High

770487

RAB5C
Ras-related protein Rab-5C

1

4

High-throughput

0.437

High

915316

Q7TMG8
Glioblastoma amplified sequence

1

1

High-throughput

0.437

High

915319

AMPH
Amphiphysin

1

6

High-throughput

0.437

High

915321

MAP6
Microtubule-associated protein 6

1

4

High-throughput

0.437

High

915322

SAM50
Sorting and assembly machinery component 50 homolog

1

2

High-throughput

0.437

High

915323

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

2

High-throughput

0.437

High

915324

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.437

High

915338

Q91VA7
Isocitrate dehydrogenase [NAD] subunit, mitochondrial

1

1

High-throughput

0.437

High

915343

LRC59
Leucine-rich repeat-containing protein 59 [Cleaved into: Leucine-rich repeat-containing protein 59, N-terminally processed]

1

4

High-throughput

0.437

High

915345

ACON
Aconitate hydratase, mitochondrial

1

1

High-throughput

0.437

High

915354

GHC1
Mitochondrial glutamate carrier 1

1

3

High-throughput

0.437

High

915355

IDH3A
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

1

1

High-throughput

0.437

High

915357

AP2B1
AP-2 complex subunit beta

1

3

High-throughput

0.437

High

915362

ADDB
Beta-adducin

1

3

High-throughput

0.437

High

915367

SEPT6
Septin-6

1

2

High-throughput

0.437

High

915372

SEPT5
Septin-5

1

2

High-throughput

0.437

High

267013

GNAZ
Guanine nucleotide-binding protein G(z) subunit alpha

1

0

High-throughput

0.249

Low

378928

THY1
Thy-1 membrane glycoprotein

1

0

High-throughput

0.249

Low

421207

ALDOC
Fructose-bisphosphate aldolase C

1

0

High-throughput

0.249

Low

686762

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

0

High-throughput

0.249

Low

845174

EAA2
Excitatory amino acid transporter 2

1

0

High-throughput

0.249

Low

866411

RP3A
Rabphilin-3A

1

0

High-throughput

0.249

Low

915271

STX1B
Syntaxin-1B

1

0

High-throughput

0.249

Low

915272

GABT
4-aminobutyrate aminotransferase, mitochondrial

1

0

High-throughput

0.249

Low

915291

VGLU1
Vesicular glutamate transporter 1

1

0

High-throughput

0.249

Low

915299

S4A10
Sodium-driven chloride bicarbonate exchanger

1

0

High-throughput

0.249

Low

915305

MOG
Myelin-oligodendrocyte glycoprotein

1

0

High-throughput

0.249

Low

915309

GPDM
Glycerol-3-phosphate dehydrogenase, mitochondrial

1

0

High-throughput

0.249

Low

915310

CLH1
Clathrin heavy chain 1

1

0

High-throughput

0.249

Low

915326

VATH
V-type proton ATPase subunit H

1

0

High-throughput

0.249

Low

915327

MIC60
MICOS complex subunit Mic60

1

0

High-throughput

0.249

Low

915331

THIL
Acetyl-CoA acetyltransferase, mitochondrial

1

0

High-throughput

0.249

Low

915332

CACB4
Voltage-dependent L-type calcium channel subunit beta-4

1

0

High-throughput

0.249

Low

915337

SFXN3
Sideroflexin-3

1

0

High-throughput

0.249

Low

915339

NDUS2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

1

0

High-throughput

0.249

Low

915341

NDUV1
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

1

0

High-throughput

0.249

Low

915347

AMPL
Cytosol aminopeptidase

1

0

High-throughput

0.249

Low

915349

PSMD8
26S proteasome non-ATPase regulatory subunit 8

1

0

High-throughput

0.249

Low

915352

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

0

High-throughput

0.249

Low

915356

ATPO
ATP synthase peripheral stalk subunit OSCP, mitochondrial

1

0

High-throughput

0.249

Low

915358

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

1

0

High-throughput

0.249

Low

915369

SUCA
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low

915371

SUCB1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025