HitPredict

Interactor 1: LCE3C (Q5T5A8)
Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A)
Gene: LCE3C

Interactor 2: KRA42 (Q9BYR5)
Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2)
Gene: KRTAP4-2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.50	0.616

Property	Details
Experiments	25416956, 32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 94 Hs			1 136
+	Hs
		1133541 LCE3C_HUMAN (1-94): 1.03e-36: 120: 100.00		KR412_HUMAN (2-136): 5.17e-26: 98.6: 64.38
+	Hs
		1133536 LCE3C_HUMAN (1-94): 1.03e-36: 120: 100.00		KRA13_HUMAN (3-135): 4.44e-22: 87.4: 34.57
+	Hs
		1133535 LCE3C_HUMAN (1-94): 1.03e-36: 120: 100.00		KR111_HUMAN (1-134): 7.05e-20: 81.6: 28.36
+	Hs
		889059 LCE3C_HUMAN (1-94): 1.03e-36: 120: 100.00		KR105_HUMAN (26-135): 1.38e-16: 75.4: 36.80
+	Hs
		888887 LCE3C_HUMAN (1-94): 1.03e-36: 120: 100.00		KR103_HUMAN (35-136): 1.08e-16: 74.7: 36.36
+	Hs
		1133545 LCE3C_HUMAN (1-94): 1.03e-36: 120: 100.00		KRA93_HUMAN (29-134): 6.33e-17: 73.9: 42.73
+	Hs
		889266 LCE3C_HUMAN (1-94): 1.03e-36: 120: 100.00		KR107_HUMAN (16-136): 3.47e-14: 69.7: 29.63
+	Hs
		889503 LCE3C_HUMAN (1-94): 1.03e-36: 120: 100.00		KR108_HUMAN (14-136): 9.72e-14: 67.4: 27.48
+	Hs
		889776 LCE3C_HUMAN (1-94): 1.03e-36: 120: 100.00		KR109_HUMAN (4-116): 3e-13: 66.6: 30.53
+	Hs
		1133546 LCE3C_HUMAN (1-94): 1.03e-36: 120: 100.00		KRA92_HUMAN (33-134): 1.36e-13: 65.8: 43.20
+	Hs
		1133547 LCE3C_HUMAN (1-94): 1.03e-36: 120: 100.00		KR411_HUMAN (52-136): 3.68e-13: 65: 47.06
+	Hs
		887732 LCE3C_HUMAN (1-94): 1.03e-36: 120: 100.00		KR10A_HUMAN (4-126): 2.33e-12: 63.5: 27.64
+	Hs
		1133544 LCE3C_HUMAN (1-94): 1.03e-36: 120: 100.00		KRA94_HUMAN (34-136): 8.37e-13: 63.1: 42.72
+	Hs
		889935 LCE3C_HUMAN (1-94): 1.03e-36: 120: 100.00		KR10B_HUMAN (2-116): 1.77e-11: 61.6: 32.52
+	Hs
		1133543 LCE3C_HUMAN (1-94): 1.03e-36: 120: 100.00		KRA98_HUMAN (43-124): 2.53e-11: 59.3: 45.35
+	Hs
		888699 LCE3C_HUMAN (1-94): 1.03e-36: 120: 100.00		KR101_HUMAN (51-135): 9.54e-11: 59.3: 35.48
+	Hs
		473289 LCE3C_HUMAN (1-94): 1.03e-36: 120: 100.00		KRA23_HUMAN (19-135): 7.72e-11: 57.3: 31.20
+	Hs
		888546 LCE3C_HUMAN (1-94): 1.03e-36: 120: 100.00		KR123_HUMAN (51-136): 9.22e-11: 56.6: 33.33
+	Hs
		889153 LCE3C_HUMAN (1-94): 1.03e-36: 120: 100.00		KR106_HUMAN (2-121): 2.72e-09: 55.8: 25.00
+	Hs
		991575 LCE3C_HUMAN (1-94): 1.03e-36: 120: 100.00		KRA11_HUMAN (3-124): 1.33e-09: 55: 24.81