HitPredict

Interactor 1: LCE1B (Q5T7P3)
Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A)
Gene: LCE1B

Interactor 2: KRA15 (Q9BYS1)
Keratin-associated protein 1-5 (High sulfur keratin-associated protein 1.5) (Keratin-associated protein 1.5)
Gene: KRTAP1-5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.561

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach, mammalian protein protein interaction trap
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 118 Hs			1 174
+	Hs
		991583 LCE1B_HUMAN (1-118): 4.85e-50: 156: 100.00		KRA11_HUMAN (1-164): 1.78e-30: 110: 79.88
+	Hs
		1134883 LCE1B_HUMAN (1-118): 4.85e-50: 156: 100.00		KRA13_HUMAN (1-173): 1.02e-24: 95.6: 77.59
+	Hs
		1134887 LCE1B_HUMAN (1-118): 4.85e-50: 156: 100.00		KR412_HUMAN (1-174): 2.08e-22: 90.6: 29.41
+	Hs
		888707 LCE1B_HUMAN (1-118): 4.85e-50: 156: 100.00		KR101_HUMAN (2-174): 1.67e-18: 82.1: 30.16
+	Hs
		888891 LCE1B_HUMAN (1-118): 4.85e-50: 156: 100.00		KR103_HUMAN (2-149): 3.08e-17: 77.5: 26.67
+	Hs
		889785 LCE1B_HUMAN (1-118): 4.85e-50: 156: 100.00		KR109_HUMAN (3-134): 1.07e-16: 77.1: 26.32
+	Hs
		889274 LCE1B_HUMAN (1-118): 4.85e-50: 156: 100.00		KR107_HUMAN (34-173): 1.11e-14: 72.5: 26.03
+	Hs
		889514 LCE1B_HUMAN (1-118): 4.85e-50: 156: 100.00		KR108_HUMAN (1-138): 3.2e-14: 70.1: 31.69
+	Hs
		887375 LCE1B_HUMAN (1-118): 4.85e-50: 156: 100.00		KR122_HUMAN (19-174): 5.75e-14: 67.1: 26.92
+	Hs
		889938 LCE1B_HUMAN (1-118): 4.85e-50: 156: 100.00		KR10B_HUMAN (10-139): 1.85e-12: 65.5: 29.23
+	Hs
		888652 LCE1B_HUMAN (1-118): 4.85e-50: 156: 100.00		KR124_HUMAN (22-113): 1.73e-13: 65.1: 29.35
+	Hs
		1134890 LCE1B_HUMAN (1-118): 4.85e-50: 156: 100.00		KRA98_HUMAN (74-174): 1.43e-12: 64: 29.70
+	Hs
		1134892 LCE1B_HUMAN (1-118): 4.85e-50: 156: 100.00		KRA93_HUMAN (3-124): 1.92e-11: 60.9: 26.23
+	Hs
		887736 LCE1B_HUMAN (1-118): 4.85e-50: 156: 100.00		KR10A_HUMAN (16-139): 1.54e-10: 59.7: 27.42
+	Hs
		889064 LCE1B_HUMAN (1-118): 4.85e-50: 156: 100.00		KR105_HUMAN (51-171): 4.1e-10: 59: 24.83
+	Hs
		889160 LCE1B_HUMAN (1-118): 4.85e-50: 156: 100.00		KR106_HUMAN (2-154): 5.91e-10: 58.6: 25.61
+	Hs
		473296 LCE1B_HUMAN (1-118): 4.85e-50: 156: 100.00		KRA23_HUMAN (19-110): 1.41e-10: 57.8: 32.98
+	Hs
		1134891 LCE1B_HUMAN (1-118): 4.85e-50: 156: 100.00		KRA94_HUMAN (74-174): 4.61e-10: 57.1: 27.72
+	Hs
		888555 LCE1B_HUMAN (1-118): 4.85e-50: 156: 100.00		KR123_HUMAN (15-106): 2.73e-09: 53.6: 35.48
+	Hs
		887318 LCE1B_HUMAN (1-118): 4.85e-50: 156: 100.00		KR121_HUMAN (15-106): 6.37e-09: 52.8: 34.41