HitPredict

Interactor 1: RC3H1 (Q5TC82)
Roquin-1 (Roquin) (EC 2.3.2.27) (RING finger and C3H zinc finger protein 1) (RING finger and CCCH-type zinc finger domain-containing protein 1) (RING finger protein 198)
Gene: RC3H1

Interactor 2: PABP5 (Q96DU9)
Polyadenylate-binding protein 5 (PABP-5) (Poly(A)-binding protein 5)
Gene: PABPC5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30209976
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003730 - mRNA 3'-UTR binding GO:0010494 - cytoplasmic stress granule
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1133 Hs			1 382
+	Hs
		1136287 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		PABP3_HUMAN (19-201): 3.02e-32: 129: 28.64
+	Hs
		582333 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		NUCL_HUMAN (4-96): 1.1e-19: 92.8: 30.11
+	Hs
		1031360 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		PABP4_HUMAN (5-199): 1.19e-17: 86.6: 15.74
+	Hs
		516550 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		PABP1_HUMAN (292-378): 3.47e-17: 85.1: 23.60
+	Hs
		1288632 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		PABP5_HUMAN (1-382): 2.22e-103: 311: 100.00
+	Hs
		1329984 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		PABP3_HUMAN (19-201): 3.02e-32: 129: 28.64
+	Hs
		582503 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		NUCL_HUMAN (4-96): 1.1e-19: 92.8: 30.11
+	Hs
		1031467 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		PABP4_HUMAN (5-199): 1.19e-17: 86.6: 15.74
+	Hs
		516698 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		PABP1_HUMAN (292-378): 3.47e-17: 85.1: 23.60