HitPredict

Interactor 1: H37 (Q5TEC6)
Histone H3-7
Gene: H3-7

Interactor 2: H2AW (Q9P0M6)
Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2)
Gene: MACROH2A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.712

Property	Details
Experiments	28514442, 33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Histone~Histone, Histone~Histone_H2A_C
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 372
+	Hs
		260833 H31_HUMAN (1-136): 1.18e-61: 187: 97.06		H2AY_HUMAN (1-371): 8.19e-156: 444: 66.31
+	Hs
		260840 H33_HUMAN (1-136): 5.9e-61: 185: 94.12		H2AY_HUMAN (1-371): 8.19e-156: 444: 66.31
+	Hs
		260915 H32_HUMAN (1-136): 1.79e-60: 184: 97.06		H2AY_HUMAN (1-371): 8.19e-156: 444: 66.31
+	Hs
		935316 H31_HUMAN (1-136): 1.18e-61: 187: 97.06		H2AW_HUMAN (1-372): 5.27e-152: 434: 100.00
+	Hs
		952668 H33_HUMAN (1-136): 5.9e-61: 185: 94.12		H2AW_HUMAN (1-372): 5.27e-152: 434: 100.00
+	Hs
		555411 H31_HUMAN (1-136): 1.18e-61: 187: 97.06		H2AX_HUMAN (1-144): 1.72e-66: 208: 57.14
+	Hs
		555416 H33_HUMAN (1-136): 5.9e-61: 185: 94.12		H2AX_HUMAN (1-144): 1.72e-66: 208: 57.14
+	Hs
		935141 H31_HUMAN (1-136): 1.18e-61: 187: 97.06		H2A1A_HUMAN (1-128): 1.35e-65: 206: 60.31
+	Mm
		935458 H31_MOUSE (1-136): 1.18e-61: 187: 97.06		Q8CGP4_MOUSE (1-126): 5.01e-65: 204: 59.69
+	Hs
		934946 H31_HUMAN (1-136): 1.18e-61: 187: 97.06		H2A2B_HUMAN (1-123): 1.24e-64: 203: 63.49
+	Hs
		935170 H31_HUMAN (1-136): 1.18e-61: 187: 97.06		H2A1J_HUMAN (1-125): 2.23e-64: 202: 60.94
+	Mm
		952759 H33_MOUSE (1-136): 5.9e-61: 185: 94.12		Q8CGP4_MOUSE (1-126): 5.01e-65: 204: 59.69
+	Hs
		391649 H31_HUMAN (1-136): 1.18e-61: 187: 97.06		H2A1B_HUMAN (1-126): 6.65e-64: 201: 60.47
+	Hs
		470336 H31_HUMAN (1-136): 1.18e-61: 187: 97.06		H2A1_HUMAN (1-126): 6.37e-64: 201: 60.47
+	Hs
		934815 H31_HUMAN (1-136): 1.18e-61: 187: 97.06		H2A2C_HUMAN (1-126): 7.57e-64: 201: 61.24
+	Hs
		934877 H31_HUMAN (1-136): 1.18e-61: 187: 97.06		H2A2A_HUMAN (1-126): 4.27e-64: 201: 62.02
+	Mm
		952264 H32_MOUSE (1-136): 1.79e-60: 184: 97.06		Q8CGP4_MOUSE (1-126): 5.01e-65: 204: 59.69
+	Hs
		952450 H33_HUMAN (1-136): 5.9e-61: 185: 94.12		H2A2B_HUMAN (1-123): 1.24e-64: 203: 63.49
+	Hs
		391655 H33_HUMAN (1-136): 5.9e-61: 185: 94.12		H2A1B_HUMAN (1-126): 6.65e-64: 201: 60.47
+	Hs
		470350 H33_HUMAN (1-136): 5.9e-61: 185: 94.12		H2A1_HUMAN (1-126): 6.37e-64: 201: 60.47