HitPredict

Interactor 1: Q5U5U6 (Q5U5U6)
Epididymis secretory protein Li 50 (Ubiquitin B)
Gene: UBB

Interactor 2: UBQL1 (Q9UMX0)
Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC-1)
Gene: UBQLN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UBA~ubiquitin, ubiquitin~ubiquitin
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 229 Hs			1 589
+	Hs
		475241 UBB_HUMAN (1-229): 4.07e-98: 286: 100.00		UBQL1_HUMAN (1-589): 1.23e-174: 509: 100.00
+	Hs
		475223 UBB_HUMAN (1-229): 4.07e-98: 286: 100.00		UBQL2_HUMAN (1-589): 9.51e-145: 433: 71.29
+	Rn
		1144285 UBC_RAT (1-181): 2.6e-61: 206: 96.13		UBQL1_RAT (1-589): 4.97e-162: 476: 86.15
+	Rn
		88976 UBC_RAT (1-181): 2.6e-61: 206: 96.13		D4AA63_RAT (1-589): 6.84e-149: 445: 65.99
+	Mm
		477045 UBC_MOUSE (1-181): 6.49e-62: 207: 96.13		UBQL2_MOUSE (1-589): 8.33e-141: 424: 65.47
+	Dm
		1375397 Q9W418_DROME (1-228): 2.1e-92: 282: 100.00		Q9VXF9_DROME (37-317): 4.08e-51: 184: 17.93
+	Pf
		1181547 Q7KQK2_PLAF7 (1-228): 2.61e-94: 282: 98.68		Q8IJS8_PLAF7 (37-351): 6.06e-38: 146: 15.30
+	Hs
		474985 UBB_HUMAN (1-229): 4.07e-98: 286: 100.00		RL40_HUMAN (37-126): 1.88e-34: 128: 30.77
+	Dm
		574862 Q9W418_DROME (1-228): 2.1e-92: 282: 100.00		RL40_DROME (37-126): 7.82e-34: 126: 29.67
+	Rn
		1144200 UBC_RAT (1-181): 2.6e-61: 206: 96.13		BAG6_RAT (24-536): 5.58e-54: 200: 16.84
+	Sc
		477189 UBI4P_YEAST (1-228): 5.66e-90: 271: 96.05		RAD23_YEAST (45-419): 1.17e-31: 128: 17.73
+	Sc
		477360 UBI4P_YEAST (1-228): 5.66e-90: 271: 96.05		DSK2_YEAST (36-243): 8.16e-32: 128: 30.73
+	Mm
		477067 UBC_MOUSE (1-181): 6.49e-62: 207: 96.13		BAG6_MOUSE (24-536): 1.29e-49: 187: 16.32
+	Mm
		57049 UBC_MOUSE (1-181): 6.49e-62: 207: 96.13		DDI2_MOUSE (47-318): 5.94e-50: 179: 14.39
+	Rn
		48892 UBC_RAT (1-181): 2.6e-61: 206: 96.13		DDI1_RAT (37-318): 7.42e-48: 174: 12.54
+	Hs
		476101 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		DDI1_HUMAN (47-318): 6.39e-53: 187: 15.60
+	Hs
		475888 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		DDI2_HUMAN (47-318): 2.03e-49: 178: 13.52
+	Hs
		475591 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		RL40_HUMAN (37-126): 1.88e-34: 128: 30.77
+	Rn
		924232 UBC_RAT (1-181): 2.6e-61: 206: 96.13		RS27A_RAT (37-107): 1.11e-12: 68: 36.11
+	Hs
		475590 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		RS27A_HUMAN (37-123): 1.1e-12: 68: 30.68