Protein: UBP54
Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin-specific peptidase 54)

Gene: UBP54, USP54
Organism: Homo sapiens
Interactions: 218
UniProt ID: Q70EL1

Gene Ontology (top 5):
GO:0004843 - cysteine-type deubiquitinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

271122

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

2

15

High-throughput

0.783

High

929523

RACK1
Small ribosomal subunit protein RACK1

2

10

High-throughput

0.700

High

1174131

FBW1B
F-box/WD repeat-containing protein 11

2

12

High-throughput

0.675

High

868567

ATX1
Ataxin-1

4

4

High-throughput

0.641

High

904761

1433G
14-3-3 protein gamma

4

20

High-throughput

0.630

High

982187

1433F
14-3-3 protein eta

4

20

High-throughput

0.630

High

473528

ATX1L
Ataxin-1-like

3

4

High-throughput

0.611

High

683480

1433B
14-3-3 protein beta/alpha

3

20

High-throughput

0.609

High

1174048

SKAP1
Src kinase-associated phosphoprotein 1

3

4

High-throughput

0.609

High

1174137

CLC11
C-type lectin domain family 11 member A

3

1

High-throughput

0.609

High

103767

G5E9A7
DM1 locus, WD repeat containing

1

18

High-throughput

0.594

High

475956

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

20

High-throughput

0.579

High

1043895

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

2

2

High-throughput

0.578

High

327286

NOE2
Noelin-2

2

1

High-throughput

0.574

High

995389

LG3BP
Galectin-3-binding protein

2

4

High-throughput

0.574

High

1022925

CDC16
Cell division cycle protein 16 homolog

2

2

High-throughput

0.574

High

1168359

THSD4
Thrombospondin type-1 domain-containing protein 4

2

1

High-throughput

0.574

High

1174145

ASB3
Ankyrin repeat and SOCS box protein 3

2

4

High-throughput

0.574

High

909723

1433E
14-3-3 protein epsilon

2

3

High-throughput

0.558

High

927205

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.558

High

1174059

SIR6
NAD-dependent protein deacylase sirtuin-6

2

3

High-throughput

0.558

High

1174139

CARD8
Caspase recruitment domain-containing protein 8

2

1

High-throughput

0.558

High

160054

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

2

High-throughput

0.553

High

169881

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

2

2

High-throughput

0.553

High

204360

MS18B
Protein Mis18-beta

2

1

High-throughput

0.553

High

212444

AAKB2
5'-AMP-activated protein kinase subunit beta-2

2

1

High-throughput

0.553

High

239459

PLPL9
85/88 kDa calcium-independent phospholipase A2

2

3

High-throughput

0.553

High

257486

CREST
Calcium-responsive transactivator

2

4

High-throughput

0.553

High

274250

STK16
Serine/threonine-protein kinase 16

2

1

High-throughput

0.553

High

277516

CCNK
Cyclin-K

2

2

High-throughput

0.553

High

301210

RHBT3
Rho-related BTB domain-containing protein 3

2

3

High-throughput

0.553

High

315572

SC24A
Protein transport protein Sec24A

2

1

High-throughput

0.553

High

539024

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

2

2

High-throughput

0.553

High

686485

OTX1
Homeobox protein OTX1

2

2

High-throughput

0.553

High

703398

CSTF2
Cleavage stimulation factor subunit 2

2

5

High-throughput

0.553

High

855108

HNRPF
Heterogeneous nuclear ribonucleoprotein F

2

9

High-throughput

0.553

High

993475

TLE5
TLE family member 5

2

2

High-throughput

0.553

High

1021226

FOXI1
Forkhead box protein I1

2

1

High-throughput

0.553

High

1037515

BFSP2
Phakinin

2

7

High-throughput

0.553

High

1075117

TCEA2
Transcription elongation factor A protein 2

2

1

High-throughput

0.553

High

1102921

QRIC1
Transcriptional regulator QRICH1

2

3

High-throughput

0.553

High

1120049

FND3B
Fibronectin type III domain-containing protein 3B

2

2

High-throughput

0.553

High

1144552

TENS2
Tensin-2

2

1

High-throughput

0.553

High

1162734

DOK6
Docking protein 6

2

1

High-throughput

0.553

High

1174041

EPMIP
EPM2A-interacting protein 1

2

2

High-throughput

0.553

High

1174046

DTX2
Probable E3 ubiquitin-protein ligase DTX2

2

6

High-throughput

0.553

High

1174047

IGFN1
Immunoglobulin-like and fibronectin type III domain-containing protein 1

2

1

High-throughput

0.553

High

1174052

CHERP
Calcium homeostasis endoplasmic reticulum protein

2

7

High-throughput

0.553

High

1174054

CCD13
Coiled-coil domain-containing protein 13

2

8

High-throughput

0.553

High

1174068

LMO3
LIM domain only protein 3

2

2

High-throughput

0.553

High

1174069

LNX1
E3 ubiquitin-protein ligase LNX

2

5

High-throughput

0.553

High

1174075

ZCH14
Zinc finger CCHC domain-containing protein 14

2

3

High-throughput

0.553

High

1174076

SHC3
SHC-transforming protein 3

2

6

High-throughput

0.553

High

1174078

PCSK5
Proprotein convertase subtilisin/kexin type 5

2

4

High-throughput

0.553

High

1174092

TEKT5
Tektin-5

2

1

High-throughput

0.553

High

1174093

TSSK3
Testis-specific serine/threonine-protein kinase 3

2

2

High-throughput

0.553

High

1174099

CAR10
Caspase recruitment domain-containing protein 10

2

8

High-throughput

0.553

High

1174104

TOLIP
Toll-interacting protein

2

1

High-throughput

0.553

High

1174105

SHRPN
Sharpin

2

1

High-throughput

0.553

High

1174106

RN208
RING finger protein 208

2

3

High-throughput

0.553

High

1174117

PRDM6
Putative histone-lysine N-methyltransferase PRDM6

2

1

High-throughput

0.553

High

1174128

TRIM1
Probable E3 ubiquitin-protein ligase MID2

2

12

High-throughput

0.553

High

1174129

CDC23
Cell division cycle protein 23 homolog

2

2

High-throughput

0.553

High

1174136

ZN148
Zinc finger protein 148

2

2

High-throughput

0.553

High

921623

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

10

High-throughput

0.553

High

980702

TLE2
Transducin-like enhancer protein 2

1

13

High-throughput

0.553

High

1146541

A16L1
Autophagy-related protein 16-1

1

8

High-throughput

0.553

High

1174058

WDTC1
WD and tetratricopeptide repeats protein 1

1

11

High-throughput

0.553

High

1174072

DCAF4
DDB1- and CUL4-associated factor 4

1

2

High-throughput

0.553

High

1174098

LST8
Target of rapamycin complex subunit LST8

1

8

High-throughput

0.553

High

1174138

FBW1A
F-box/WD repeat-containing protein 1A

1

8

High-throughput

0.553

High

1145807

CP135
Centrosomal protein of 135 kDa

2

7

High-throughput

0.533

High

1174140

NINL
Ninein-like protein

2

11

High-throughput

0.533

High

1174115

NXT2
NTF2-related export protein 2

1

1

High-throughput

0.523

High

180053

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

1

High-throughput

0.489

High

568990

CAN2
Calpain-2 catalytic subunit

1

1

High-throughput

0.489

High

661315

S10A2
Protein S100-A2

1

4

High-throughput

0.489

High

729122

K22E
Keratin, type II cytoskeletal 2 epidermal

1

5

High-throughput

0.489

High

934270

CSK21
Casein kinase II subunit alpha

1

3

High-throughput

0.489

High

943312

TCPB
T-complex protein 1 subunit beta

1

12

High-throughput

0.489

High

1020758

TRAF2
TNF receptor-associated factor 2

1

18

High-throughput

0.489

High

1023187

FLII
Protein flightless-1 homolog

1

3

High-throughput

0.489

High

1128502

HABP4
Intracellular hyaluronan-binding protein 4

1

3

High-throughput

0.489

High

1174051

VRK3
Serine/threonine-protein kinase VRK3

1

2

High-throughput

0.489

High

1174060

ABTB2
Ankyrin repeat and BTB/POZ domain-containing protein 2

1

5

High-throughput

0.489

High

1174067

SNIP1
Smad nuclear-interacting protein 1

1

1

High-throughput

0.489

High

1174081

TRI52
E3 ubiquitin-protein ligase TRIM52

1

12

High-throughput

0.489

High

1174083

RMXL1
RNA binding motif protein, X-linked-like-1

1

3

High-throughput

0.489

High

1174094

BUD13
BUD13 homolog

1

3

High-throughput

0.489

High

1174107

PDCL3
Phosducin-like protein 3

1

1

High-throughput

0.489

High

1174118

DISC1
Disrupted in schizophrenia 1 protein

1

1

High-throughput

0.489

High

1174126

TSP50
Probable threonine protease PRSS50

1

2

High-throughput

0.489

High

1174132

PNMA2
Paraneoplastic antigen Ma2

1

3

High-throughput

0.489

High

1174142

CRYL1
Lambda-crystallin homolog

1

4

High-throughput

0.489

High

1174147

NEMO
NF-kappa-B essential modulator

1

10

High-throughput

0.489

High

360078

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

7

High-throughput

0.470

High

1115799

Q49AR9
ANKS1A protein

1

3

High-throughput

0.470

High

1174043

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

2

High-throughput

0.470

High

1174085

Q96EJ4
PLAC8 protein

1

1

High-throughput

0.470

High

1174148

X5D778
Ankyrin repeat domain 11 isoform A

1

6

High-throughput

0.470

High

869481

ATN1
Atrophin-1

1

5

High-throughput

0.464

High

208842

CHM2A
Charged multivesicular body protein 2a

1

4

Small-scale

0.457

High

1174042

CHM1B
Charged multivesicular body protein 1b

1

5

Small-scale

0.457

High

1174082

CHM4C
Charged multivesicular body protein 4c

1

4

Small-scale

0.457

High

1174087

CHMP6
Charged multivesicular body protein 6

1

5

Small-scale

0.457

High

1174101

CHM4A
Charged multivesicular body protein 4a

1

4

Small-scale

0.457

High

1174108

CHM4B
Charged multivesicular body protein 4b

1

4

Small-scale

0.457

High

1174114

CHM1A
Charged multivesicular body protein 1a

1

7

Small-scale

0.457

High

1174123

CHMP5
Charged multivesicular body protein 5

1

7

Small-scale

0.457

High

1174135

CHM2B
Charged multivesicular body protein 2b

1

8

Small-scale

0.457

High

1174144

CHMP3
Charged multivesicular body protein 3

1

7

Small-scale

0.457

High

1134024

AT7L2
Ataxin-7-like protein 2

1

10

High-throughput

0.439

High

1164749

ANR11
Ankyrin repeat domain-containing protein 11

1

6

High-throughput

0.439

High

1174077

ANS1A
Ankyrin repeat and SAM domain-containing protein 1A

1

4

High-throughput

0.439

High

1174121

PLAC8
Placenta-specific gene 8 protein

1

1

High-throughput

0.439

High

129021

PLK4
Serine/threonine-protein kinase PLK4

1

6

High-throughput

0.437

High

164408

TRI66
Tripartite motif-containing protein 66

1

11

High-throughput

0.437

High

169184

MUSK
Muscle, skeletal receptor tyrosine-protein kinase

1

2

High-throughput

0.437

High

308818

KI20A
Kinesin-like protein KIF20A

1

3

High-throughput

0.437

High

325783

LATS1
Serine/threonine-protein kinase LATS1

1

2

High-throughput

0.437

High

374428

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

3

High-throughput

0.437

High

411775

LCK
Tyrosine-protein kinase Lck

1

3

High-throughput

0.437

High

444402

K1C19
Keratin, type I cytoskeletal 19

1

8

High-throughput

0.437

High

487544

ANDR
Androgen receptor

1

9

High-throughput

0.437

High

647033

1433T
14-3-3 protein theta

1

20

High-throughput

0.437

High

684152

1433S
14-3-3 protein sigma

1

20

High-throughput

0.437

High

717177

CTNB1
Catenin beta-1

1

10

High-throughput

0.437

High

741063

ZEB1
Zinc finger E-box-binding homeobox 1

1

4

Small-scale

0.437

High

781924

PERI
Peripherin

1

5

High-throughput

0.437

High

820957

PRC2A
Protein PRRC2A

1

7

High-throughput

0.437

High

876425

AFAD
Afadin

1

6

High-throughput

0.437

High

882382

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

8

High-throughput

0.437

High

1089517

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

6

High-throughput

0.437

High

1148110

RNF43
E3 ubiquitin-protein ligase RNF43

1

3

High-throughput

0.437

High

1166148

OLFM4
Olfactomedin-4

1

1

High-throughput

0.437

High

1168553

SYNE3
Nesprin-3

1

8

High-throughput

0.437

High

1168765

MEX3B
RNA-binding protein MEX3B

1

1

High-throughput

0.437

High

1172656

CE128
Centrosomal protein of 128 kDa

1

8

High-throughput

0.437

High

1174045

PATL1
Protein PAT1 homolog 1

1

6

High-throughput

0.437

High

1174050

CCNJL
Cyclin-J-like protein

1

3

High-throughput

0.437

High

1174056

NIN
Ninein

1

11

High-throughput

0.437

High

1174064

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

8

High-throughput

0.437

High

1174070

BICD2
Protein bicaudal D homolog 2

1

11

High-throughput

0.437

High

1174071

PARD3
Partitioning defective 3 homolog

1

3

High-throughput

0.437

High

1174073

NUDC2
NudC domain-containing protein 2

1

1

High-throughput

0.437

High

1174088

BICD1
Protein bicaudal D homolog 1

1

11

High-throughput

0.437

High

1174090

FUBP3
Far upstream element-binding protein 3

1

8

High-throughput

0.437

High

1174095

LZTS2
Leucine zipper putative tumor suppressor 2

1

7

High-throughput

0.437

High

1174100

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

1

High-throughput

0.437

High

1174102

CPEB1
Cytoplasmic polyadenylation element-binding protein 1

1

10

High-throughput

0.437

High

1174109

PKHA4
Pleckstrin homology domain-containing family A member 4

1

5

High-throughput

0.437

High

1174113

TNR6C
Trinucleotide repeat-containing gene 6C protein

1

9

High-throughput

0.437

High

1174119

LATS2
Serine/threonine-protein kinase LATS2

1

2

High-throughput

0.437

High

1174120

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

1

High-throughput

0.437

High

1174125

ZO2
Tight junction protein ZO-2

1

3

High-throughput

0.437

High

1174127

HOOK1
Protein Hook homolog 1

1

10

High-throughput

0.437

High

1174130

ANC2
Anaphase-promoting complex subunit 2

1

3

High-throughput

0.437

High

1174134

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

6

High-throughput

0.437

High

1174141

R3HD2
R3H domain-containing protein 2

1

5

High-throughput

0.437

High

1174124

PP4RL
Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like

1

2

High-throughput

0.407

High

1174053

BBS7
Bardet-Biedl syndrome 7 protein

2

0

High-throughput

0.328

High

1174063

GALD1
Glutamine amidotransferase-like class 1 domain-containing protein 1

2

0

High-throughput

0.328

High

1174079

PIGT
GPI transamidase component PIG-T

2

0

High-throughput

0.328

High

1174091

VPS39
Vam6/Vps39-like protein

2

0

High-throughput

0.328

High

1174103

IQCN
IQ domain-containing protein N

2

0

High-throughput

0.328

High

1174133

CELA1
Chymotrypsin-like elastase family member 1

2

0

High-throughput

0.328

High

67170

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

146515

BHE40
Class E basic helix-loop-helix protein 40

2

0

High-throughput

0.316

High

198013

PHF1
PHD finger protein 1

2

0

High-throughput

0.316

High

270990

GCM2
Chorion-specific transcription factor GCMb

2

0

High-throughput

0.316

High

308106

VENTX
Homeobox protein VENTX

2

0

High-throughput

0.316

High

327900

TBX6
T-box transcription factor TBX6

2

0

High-throughput

0.316

High

474618

PRR35
Proline-rich protein 35

2

0

High-throughput

0.316

High

678938

HXC8
Homeobox protein Hox-C8

2

0

High-throughput

0.316

High

727550

HNF1B
Hepatocyte nuclear factor 1-beta

2

0

High-throughput

0.316

High

735067

ZNF76
Zinc finger protein 76

2

0

High-throughput

0.316

High

1093077

INSC
Protein inscuteable homolog

2

0

High-throughput

0.316

High

1115332

PKHN1
Pleckstrin homology domain-containing family N member 1

2

0

High-throughput

0.316

High

1150445

TTC19
Tetratricopeptide repeat protein 19, mitochondrial

2

0

High-throughput

0.316

High

1170167

RBPS2
RNA-binding protein with multiple splicing 2

2

0

High-throughput

0.316

High

1174038

MED25
Mediator of RNA polymerase II transcription subunit 25

2

0

High-throughput

0.316

High

1174039

KCTD9
BTB/POZ domain-containing protein KCTD9

2

0

High-throughput

0.316

High

1174044

AP2D
Transcription factor AP-2-delta

2

0

High-throughput

0.316

High

1174055

EXOC8
Exocyst complex component 8

2

0

High-throughput

0.316

High

1174057

CCD24
Coiled-coil domain-containing protein 24

2

0

High-throughput

0.316

High

1174062

SMYD1
Histone-lysine N-methyltransferase SMYD1

2

0

High-throughput

0.316

High

1174074

SEN15
tRNA-splicing endonuclease subunit Sen15

2

0

High-throughput

0.316

High

1174080

TET5B
Terminal nucleotidyltransferase 5B

2

0

High-throughput

0.316

High

1174084

FBX17
F-box only protein 17

2

0

High-throughput

0.316

High

1174089

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

2

0

High-throughput

0.316

High

1174096

NUD22
Uridine diphosphate glucose pyrophosphatase NUDT22

2

0

High-throughput

0.316

High

1174097

RAMAC
RNA guanine-N7 methyltransferase activating subunit

2

0

High-throughput

0.316

High

1174110

F124B
Protein FAM124B

2

0

High-throughput

0.316

High

1174111

ARMC7
Armadillo repeat-containing protein 7

2

0

High-throughput

0.316

High

1174116

DMRT3
Doublesex- and mab-3-related transcription factor 3

2

0

High-throughput

0.316

High

1174146

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

2

0

High-throughput

0.316

High

237246

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

0

High-throughput

0.299

High

1101725

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.279

Low

1174061

PR38A
Pre-mRNA-splicing factor 38A

1

0

High-throughput

0.279

Low

1174065

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.279

Low

1174066

RP9
Retinitis pigmentosa 9 protein

1

0

High-throughput

0.279

Low

1174086

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.279

Low

1174112

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.279

Low

1174143

CDIN1
CDAN1-interacting nuclease 1

1

0

High-throughput

0.279

Low

1174049

Q86WV8
TSC complex subunit 1

1

0

High-throughput

0.268

Low

166266

GRRE1
Granule associated Rac and RHOG effector protein 1

1

0

High-throughput

0.249

Low

279608

FLOT1
Flotillin-1

1

0

High-throughput

0.249

Low

644279

TTP
mRNA decay activator protein ZFP36

1

0

High-throughput

0.249

Low

665274

EPHA2
Ephrin type-A receptor 2

1

0

High-throughput

0.249

Low

940470

CXAR
Coxsackievirus and adenovirus receptor

1

0

High-throughput

0.249

Low

1074353

STIL
SCL-interrupting locus protein

1

0

High-throughput

0.249

Low

1084064

OCLN
Occludin

1

0

High-throughput

0.249

Low

1101131

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

1136137

RC3H1
Roquin-1

1

0

High-throughput

0.249

Low

1146107

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low

1170297

ZBT49
Zinc finger and BTB domain-containing protein 49

1

0

High-throughput

0.249

Low

1174040

DET1
DET1 homolog

1

0

High-throughput

0.249

Low

1174122

SPN90
NCK-interacting protein with SH3 domain

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024