HitPredict

Interactor 1: UBE2U (Q5VVX9)
Ubiquitin-conjugating enzyme E2 U (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme U) (Ubiquitin carrier protein U) (Ubiquitin-protein ligase U)
Gene: UBE2U

Interactor 2: Q6NR77 (Q6NR77)
Ring finger protein 28
Gene: Q6NR77

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	19690564
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 321 Hs			1 346
+	Hs
		1138879 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		Q6GX22_HUMAN (14-329): 9.44e-83: 266: 23.65
+	Hs
		1138897 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		TRI63_HUMAN (1-326): 2.65e-82: 255: 99.39
+	Hs
		1138918 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		TRI54_HUMAN (7-337): 1.65e-74: 236: 60.24
+	Hs
		1138921 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		TRIM2_HUMAN (10-327): 2.67e-64: 218: 19.39
+	Hs
		262178 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		TRIM3_HUMAN (9-339): 3.46e-63: 215: 17.30
+	Hs
		1138920 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		TRIM5_HUMAN (10-345): 3.59e-64: 213: 18.34
+	Hs
		536873 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		TRI27_HUMAN (8-335): 2.28e-62: 209: 20.12
+	Hs
		1138883 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		TRI46_HUMAN (6-339): 4.94e-60: 207: 24.88
+	Hs
		1138878 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		TRI68_HUMAN (8-333): 8.17e-62: 206: 15.77
+	Hs
		1138928 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		TRIM1_HUMAN (11-343): 1.43e-57: 200: 21.70
+	Hs
		1151762 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		Q6GX22_HUMAN (14-329): 9.44e-83: 266: 23.65
+	Hs
		175730 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		TRI18_HUMAN (14-329): 6.89e-83: 266: 23.65
+	Hs
		1317493 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		TRI54_HUMAN (7-337): 1.65e-74: 236: 60.24
+	Hs
		1318358 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		TRIM8_HUMAN (15-322): 8.1e-65: 216: 20.78
+	Hs
		262201 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		TRIM3_HUMAN (9-339): 3.46e-63: 215: 17.30
+	Hs
		1285831 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		TRI43_HUMAN (10-338): 7.9e-64: 210: 14.59
+	Hs
		537142 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		TRI27_HUMAN (8-335): 2.28e-62: 209: 20.12
+	Hs
		1318532 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		TRI31_HUMAN (8-301): 1.93e-60: 201: 22.45
+	Hs
		1313765 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		TRI62_HUMAN (16-276): 1.27e-16: 82.4: 24.35
+	Hs
		1204911 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		TRI50_HUMAN (14-250): 1.38e-14: 76.3: 25.00