HitPredict

Interactor 1: UBE2U (Q5VVX9)
Ubiquitin-conjugating enzyme E2 U (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme U) (Ubiquitin carrier protein U) (Ubiquitin-protein ligase U)
Gene: UBE2U

Interactor 2: TRIM1 (Q9UJV3)
Probable E3 ubiquitin-protein ligase MID2 (EC 2.3.2.27) (Midin-2) (Midline defect 2) (Midline-2) (RING finger protein 60) (RING-type E3 ubiquitin transferase MID2) (Tripartite motif-containing protein 1)
Gene: MID2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.555

Property	Details
Experiments	19690564
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 321 Hs			1 735
+	Hs
		1138879 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		Q6GX22_HUMAN (21-735): 0: 550: 95.66
+	Hs
		1151762 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		Q6GX22_HUMAN (21-735): 0: 550: 95.66
+	Hs
		1138883 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		TRI46_HUMAN (18-701): 3.81e-85: 286: 20.05
+	Hs
		175730 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		TRI18_HUMAN (21-717): 8.76e-175: 518: 72.60
+	Hs
		1138880 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		Q6NR77_HUMAN (19-401): 1.74e-84: 272: 23.65
+	Hs
		1138897 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		TRI63_HUMAN (19-400): 2.79e-84: 272: 23.71
+	Hs
		1138921 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		TRIM2_HUMAN (8-524): 1.29e-57: 210: 17.77
+	Hs
		1138918 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		TRI54_HUMAN (184-400): 2.63e-53: 190: 23.96
+	Hs
		536873 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		TRI27_HUMAN (16-340): 1.18e-23: 107: 14.15
+	Hs
		135028 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		TRI38_HUMAN (16-269): 6.94e-21: 98.2: 17.12
+	Hs
		1138878 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		TRI68_HUMAN (126-458): 2.92e-19: 93.6: 14.36
+	Hs
		734651 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		TRI23_HUMAN (28-272): 6.41e-17: 86.7: 24.71
+	Hs
		1052807 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		TRI25_HUMAN (24-706): 9.41e-99: 319: 20.96
+	Hs
		1318358 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		TRIM8_HUMAN (16-417): 5.14e-61: 216: 20.34
+	Hs
		1318738 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		TRIM2_HUMAN (8-524): 1.29e-57: 210: 17.77
+	Hs
		1317493 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		TRI54_HUMAN (184-400): 2.63e-53: 190: 23.96
+	Hs
		1313765 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		TRI62_HUMAN (114-458): 1.79e-32: 133: 15.47
+	Hs
		537142 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		TRI27_HUMAN (16-340): 1.18e-23: 107: 14.15
+	Hs
		135045 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		TRI38_HUMAN (16-269): 6.94e-21: 98.2: 17.12
+	Hs
		734819 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		TRI23_HUMAN (28-272): 6.41e-17: 86.7: 24.71