Protein: SC31A
Protein transport protein Sec31A (ABP125) (ABP130) (SEC31-like protein 1) (SEC31-related protein A) (Web1-like protein)

Gene: SC31A, SEC31A
Organism: Homo sapiens
Interactions: 135
UniProt ID: O94979

Gene Ontology (top 5):
GO:0005198 - structural molecule activity
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

323855

SEC13
Protein SEC13 homolog

9

19

Small-scale

0.981

High

276400

PDCD6
Programmed cell death protein 6

6

4

Small-scale

0.740

High

323902

SCYL1
N-terminal kinase-like protein

5

2

High-throughput

0.722

High

323878

KLH12
Kelch-like protein 12

5

1

Small-scale

0.721

High

323897

TFG
Protein TFG

4

13

High-throughput

0.699

High

323926

S23IP
SEC23-interacting protein

3

6

Small-scale

0.667

High

323819

P53
Cellular tumor antigen p53

3

4

Small-scale

0.656

High

323871

CUL3
Cullin-3

3

20

Small-scale

0.656

High

240349

PRKN
E3 ubiquitin-protein ligase parkin

3

14

High-throughput

0.640

High

323848

GNPI1
Glucosamine-6-phosphate deaminase 1

2

2

High-throughput

0.628

High

323920

PEF1
Peflin

2

4

Small-scale

0.624

High

323863

NOP14
Nucleolar protein 14

3

1

High-throughput

0.616

High

323834

VCAM1
Vascular cell adhesion protein 1

2

1

High-throughput

0.601

High

105001

APRIO
Alternative prion protein

3

5

Small-scale

0.586

High

323859

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

2

6

High-throughput

0.584

High

323875

SC23B
Protein transport protein Sec23B

2

8

Small-scale

0.584

High

323898

STAM1
Signal transducing adapter molecule 1

2

5

Small-scale

0.584

High

323880

A16L1
Autophagy-related protein 16-1

1

17

High-throughput

0.575

High

323906

NOC4L
Nucleolar complex protein 4 homolog

2

3

High-throughput

0.574

High

323868

REL
Proto-oncogene c-Rel

1

5

High-throughput

0.573

High

323854

TERA
Transitional endoplasmic reticulum ATPase

2

7

High-throughput

0.571

High

323924

ARI1
E3 ubiquitin-protein ligase ARIH1

1

11

High-throughput

0.561

High

323879

FHL5
Four and a half LIM domains protein 5

2

3

High-throughput

0.553

High

323837

APC
Adenomatous polyposis coli protein

1

11

High-throughput

0.541

High

323894

TSC1
Hamartin

1

20

High-throughput

0.541

High

184782

SPTC1
Serine palmitoyltransferase 1

1

1

High-throughput

0.536

High

323838

MOES
Moesin

1

3

High-throughput

0.536

High

323849

TMEDA
Transmembrane emp24 domain-containing protein 10

1

10

High-throughput

0.536

High

323857

RAB14
Ras-related protein Rab-14

1

6

High-throughput

0.536

High

323872

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

10

High-throughput

0.536

High

323877

GRDN
Girdin

1

17

High-throughput

0.536

High

323895

PGTA
Geranylgeranyl transferase type-2 subunit alpha

1

1

High-throughput

0.536

High

323818

NTRK1
High affinity nerve growth factor receptor

2

19

High-throughput

0.533

High

323923

ALK
ALK tyrosine kinase receptor

2

19

High-throughput

0.533

High

323886

LUZP1
Leucine zipper protein 1

1

17

High-throughput

0.515

High

323904

GORS1
Golgi reassembly-stacking protein 1

1

0

High-throughput

0.513

High

323845

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

7

Small-scale

0.501

High

323853

MYOM2
Myomesin-2

1

4

High-throughput

0.494

High

323901

LCOR
Ligand-dependent corepressor

1

2

High-throughput

0.494

High

323908

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

1

High-throughput

0.489

High

261748

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.486

High

323830

TNNT1
Troponin T, slow skeletal muscle

1

0

High-throughput

0.486

High

125114

LEG9
Galectin-9

1

5

High-throughput

0.479

High

154926

BHE40
Class E basic helix-loop-helix protein 40

1

3

Small-scale

0.479

High

156798

CTRO
Citron Rho-interacting kinase

1

14

High-throughput

0.479

High

172352

XPO1
Exportin-1

1

12

High-throughput

0.479

High

179776

BET1
BET1 homolog

1

4

High-throughput

0.479

High

291155

NU155
Nuclear pore complex protein Nup155

1

3

High-throughput

0.479

High

296406

STAM2
Signal transducing adapter molecule 2

1

8

Small-scale

0.479

High

319080

SC24D
Protein transport protein Sec24D

1

7

Small-scale

0.479

High

323812

MRP6
ATP-binding cassette sub-family C member 6

1

1

Small-scale

0.479

High

323813

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

10

High-throughput

0.479

High

323814

MYC
Myc proto-oncogene protein

1

17

High-throughput

0.479

High

323817

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

9

High-throughput

0.479

High

323820

RLA2
Large ribosomal subunit protein P2

1

2

High-throughput

0.479

High

323822

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.479

High

323823

PARP1
Poly [ADP-ribose] polymerase 1

1

8

High-throughput

0.479

High

323824

FURIN
Furin

1

4

High-throughput

0.479

High

323825

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

11

Small-scale

0.479

High

323827

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.479

High

323832

PGFRA
Platelet-derived growth factor receptor alpha

1

12

High-throughput

0.479

High

323833

CXA1
Gap junction alpha-1 protein

1

2

High-throughput

0.479

High

323835

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

1

High-throughput

0.479

High

323836

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.479

High

323841

STIP1
Stress-induced-phosphoprotein 1

1

12

High-throughput

0.479

High

323843

VGFR3
Vascular endothelial growth factor receptor 3

1

12

High-throughput

0.479

High

323844

BRCA1
Breast cancer type 1 susceptibility protein

1

10

High-throughput

0.479

High

323846

CCNF
Cyclin-F

1

7

High-throughput

0.479

High

323850

EMD
Emerin

1

2

High-throughput

0.479

High

323851

MECP2
Methyl-CpG-binding protein 2

1

11

High-throughput

0.479

High

323852

SC24C
Protein transport protein Sec24C

1

7

Small-scale

0.479

High

323856

UBC12
NEDD8-conjugating enzyme Ubc12

1

9

High-throughput

0.479

High

323860

RS18
Small ribosomal subunit protein uS13

1

3

High-throughput

0.479

High

323861

RUXF
Small nuclear ribonucleoprotein F

1

6

High-throughput

0.479

High

323862

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

6

High-throughput

0.479

High

323864

HSF1
Heat shock factor protein 1

1

3

High-throughput

0.479

High

323865

KIF23
Kinesin-like protein KIF23

1

11

High-throughput

0.479

High

323866

CAV1
Caveolin-1

1

1

High-throughput

0.479

High

323867

TF65
Transcription factor p65

1

5

High-throughput

0.479

High

323870

BIRC3
Baculoviral IAP repeat-containing protein 3

1

6

High-throughput

0.479

High

323873

KIF14
Kinesin-like protein KIF14

1

8

High-throughput

0.479

High

323874

SC23A
Protein transport protein Sec23A

1

8

Small-scale

0.479

High

323876

NTRK3
NT-3 growth factor receptor

1

19

High-throughput

0.479

High

323881

VIR
Protein virilizer homolog

1

4

High-throughput

0.479

High

323882

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

323883

LMTK1
Serine/threonine-protein kinase LMTK1

1

20

High-throughput

0.479

High

323884

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.479

High

323890

SERB1
SERPINE1 mRNA-binding protein 1

1

5

High-throughput

0.479

High

323891

RIN3
Ras and Rab interactor 3

1

12

High-throughput

0.479

High

323892

ASB11
Ankyrin repeat and SOCS box protein 11

1

5

High-throughput

0.479

High

323893

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

5

High-throughput

0.479

High

323896

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

323899

CHM4C
Charged multivesicular body protein 4c

1

4

High-throughput

0.479

High

323900

OPTN
Optineurin

1

20

High-throughput

0.479

High

323903

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

4

High-throughput

0.479

High

323909

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

5

High-throughput

0.479

High

323910

PKHA4
Pleckstrin homology domain-containing family A member 4

1

17

High-throughput

0.479

High

323911

ALG2
Alpha-1,3/1,6-mannosyltransferase ALG2

1

1

Small-scale

0.479

High

323914

MYO10
Unconventional myosin-X

1

2

Small-scale

0.479

High

323915

SAR1A
Small COPII coat GTPase SAR1A

1

13

High-throughput

0.479

High

323917

PIHD1
PIH1 domain-containing protein 1

1

1

High-throughput

0.479

High

323918

TLS1
Splicing factor C9orf78

1

2

High-throughput

0.479

High

323921

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

323922

TBK1
Serine/threonine-protein kinase TBK1

1

4

High-throughput

0.479

High

323925

SAR1B
Small COPII coat GTPase SAR1B

1

16

High-throughput

0.479

High

323919

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.458

High

323916

DISC1
Disrupted in schizophrenia 1 protein

1

1

High-throughput

0.457

High

254695

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

3

High-throughput

0.445

High

323815

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

5

High-throughput

0.445

High

323826

TAU
Microtubule-associated protein tau

1

16

High-throughput

0.445

High

273246

T22D2
TSC22 domain family protein 2

1

20

Small-scale

0.439

High

323905

UBAC1
Ubiquitin-associated domain-containing protein 1

1

0

High-throughput

0.438

High

139788

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

1

High-throughput

0.437

High

179587

MUSK
Muscle, skeletal receptor tyrosine-protein kinase

1

20

High-throughput

0.437

High

323811

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.437

High

323816

MYCN
N-myc proto-oncogene protein

1

18

High-throughput

0.437

High

323821

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

20

High-throughput

0.437

High

323829

ITA4
Integrin alpha-4

1

2

High-throughput

0.437

High

323831

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.437

High

323839

EPHA2
Ephrin type-A receptor 2

1

9

High-throughput

0.437

High

323840

EPHA8
Ephrin type-A receptor 8

1

6

High-throughput

0.437

High

323842

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.437

High

323847

GATA4
Transcription factor GATA-4

1

13

Small-scale

0.437

High

323858

WDR5
WD repeat-containing protein 5

1

18

High-throughput

0.437

High

323869

TIF1B
Transcription intermediary factor 1-beta

1

8

High-throughput

0.437

High

323888

CXD3
Gap junction delta-3 protein

1

2

High-throughput

0.437

High

323913

K1549
UPF0606 protein KIAA1549

1

13

High-throughput

0.437

High

323907

ZDHC5
Palmitoyltransferase ZDHHC5

1

6

High-throughput

0.407

High

323912

VIAAT
Vesicular inhibitory amino acid transporter

1

1

High-throughput

0.407

High

188759

TMPS2
Transmembrane protease serine 2

1

0

High-throughput

0.249

Low

323828

IFM1
Interferon-induced transmembrane protein 1

1

0

High-throughput

0.249

Low

323887

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

62435

S35F4
Solute carrier family 35 member F4

1

0

High-throughput

0.232

Low

323885

NCKX5
Sodium/potassium/calcium exchanger 5

1

0

High-throughput

0.232

Low

323889

SVOPL
Putative transporter SVOPL

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025