HitPredict

Interactor 1: TAF3 (Q5VWG9)
Transcription initiation factor TFIID subunit 3 (140 kDa TATA box-binding protein-associated factor) (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (TAF(II)140) (TAF140) (TAFII-140) (TAFII140)
Gene: TAF3

Interactor 2: KAT2A (Q92830)
Histone acetyltransferase KAT2A (EC 2.3.1.48) (General control of amino acid synthesis protein 5-like 2) (Histone acetyltransferase GCN5) (hGCN5) (Histone glutaryltransferase KAT2A) (EC 2.3.1.-) (Histone succinyltransferase KAT2A) (EC 2.3.1.-) (Lysine acetyltransferase 2A) (STAF97)
Gene: KAT2A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	11438666
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Bromodomain~PHD
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 929 Hs			1 837
+	Hs
		631460 TAF3_HUMAN (1-914): 6.23e-88: 302: 100.00		BRD2_HUMAN (691-837): 3.87e-36: 148: 27.63
+	Hs
		1066999 TAF3_HUMAN (1-914): 6.23e-88: 302: 100.00		BRD3_HUMAN (694-833): 1.21e-33: 140: 25.00
+	Hs
		244558 TAF3_HUMAN (1-914): 6.23e-88: 302: 100.00		BRD4_HUMAN (657-833): 1.8e-30: 131: 21.43
+	Hs
		244466 PLEC_HUMAN (30-873): 1.38e-72: 265: 10.21		BRD4_HUMAN (657-833): 1.8e-30: 131: 21.43
+	Hs
		1139022 TAF3_HUMAN (1-914): 6.23e-88: 302: 100.00		PHIP_HUMAN (729-831): 2.23e-15: 83.3: 21.70
+	Hs
		600164 TAF3_HUMAN (1-914): 6.23e-88: 302: 100.00		TAF1_HUMAN (733-831): 8.58e-09: 61.6: 30.30
+	Hs
		998710 MDC1_HUMAN (6-886): 7.09e-49: 191: 11.56		EP300_HUMAN (652-832): 2.03e-37: 154: 19.02
+	Hs
		1057027 MDC1_HUMAN (6-886): 7.09e-49: 191: 11.56		TRI33_HUMAN (630-836): 1.1e-36: 151: 19.74
+	Hs
		631425 MDC1_HUMAN (6-886): 7.09e-49: 191: 11.56		BRD2_HUMAN (691-837): 3.87e-36: 148: 27.63
+	Hs
		1056838 MDC1_HUMAN (6-886): 7.09e-49: 191: 11.56		BRD3_HUMAN (694-833): 1.21e-33: 140: 25.00
+	Hs
		170456 RSF1_HUMAN (161-915): 1.32e-37: 155: 10.46		TIF1A_HUMAN (626-832): 1.23e-44: 176: 22.86
+	Hs
		244438 MDC1_HUMAN (6-886): 7.09e-49: 191: 11.56		BRD4_HUMAN (657-833): 1.8e-30: 131: 21.43
+	Hs
		999001 RSF1_HUMAN (161-915): 1.32e-37: 155: 10.46		EP300_HUMAN (652-832): 2.03e-37: 154: 19.02
+	Hs
		1302688 RSF1_HUMAN (161-915): 1.32e-37: 155: 10.46		TRI33_HUMAN (630-836): 1.1e-36: 151: 19.74
+	Hs
		631557 RSF1_HUMAN (161-915): 1.32e-37: 155: 10.46		BRD2_HUMAN (691-837): 3.87e-36: 148: 27.63
+	Hs
		1067107 RSF1_HUMAN (161-915): 1.32e-37: 155: 10.46		BRD3_HUMAN (694-833): 1.21e-33: 140: 25.00
+	Hs
		244826 RSF1_HUMAN (161-915): 1.32e-37: 155: 10.46		BRD4_HUMAN (657-833): 1.8e-30: 131: 21.43
+	Hs
		1067096 CHAP1_HUMAN (118-739): 9.43e-30: 128: 11.47		BRD3_HUMAN (694-833): 1.21e-33: 140: 25.00
+	Hs
		244791 CHAP1_HUMAN (118-739): 9.43e-30: 128: 11.47		BRD4_HUMAN (657-833): 1.8e-30: 131: 21.43
+	Hs
		1262802 RSF1_HUMAN (161-915): 1.32e-37: 155: 10.46		PHIP_HUMAN (729-831): 2.23e-15: 83.3: 21.70