Interactor 1: RN123 (Q5XPI4)
E3 ubiquitin-protein ligase RNF123 (EC 2.3.2.27) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123)
Gene: RNF123

Interactor 2: IFIH1 (Q9BYX4)
Interferon-induced helicase C domain-containing protein 1 (EC 3.6.4.13) (Clinically amyopathic dermatomyositis autoantigen 140 kDa) (CADM-140 autoantigen) (Helicase with 2 CARD domains) (Helicard) (Interferon-induced with helicase C domain protein 1) (Melanoma differentiation-associated protein 5) (MDA-5) (Murabutide down-regulated protein) (RIG-I-like receptor 2) (RLR-2) (RNA helicase-DEAD box protein 116)
Gene: IFIH1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.50 1.00 0.713

The method score is based on:

Property Details
Experiments 27312109
Identification Methods two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Helicase_C~SPRY
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 1314
Hs

1 1025
+ Mm
+ Hs
+ Hs
+ Hs
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+ Hs
+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024