HitPredict

Interactor 1: FBXW9 (Q5XUX1)
F-box/WD repeat-containing protein 9 (F-box and WD-40 domain-containing protein 9)
Gene: FBXW9

Interactor 2: HERC5 (Q9UII4)
E3 ISG15--protein ligase HERC5 (EC 2.3.2.-) (Cyclin-E-binding protein 1) (HECT domain and RCC1-like domain-containing protein 5)
Gene: HERC5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35671810
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 458 Hs			1 1024
+	Hs
		1281460 FBXW7_HUMAN (28-410): 1.22e-75: 252: 16.03		HERC5_HUMAN (1-1024): 0: 1123: 100.00
+	Hs
		1355831 FBW1A_HUMAN (51-222): 1.02e-11: 69.1: 10.38		HERC5_HUMAN (1-1024): 0: 1123: 100.00
+	Hs
		903156 WDR5_HUMAN (35-203): 9.39e-13: 71.1: 10.73		UBE3A_HUMAN (414-1024): 1.12e-172: 529: 25.37
+	Hs
		125310 WDR5_HUMAN (35-203): 9.39e-13: 71.1: 10.73		WWP2_HUMAN (599-1024): 1.14e-167: 516: 22.02
+	Hs
		808327 FBW1A_HUMAN (51-222): 1.02e-11: 69.1: 10.38		NEDD4_HUMAN (652-1023): 3.7e-161: 511: 26.04
+	Hs
		1334881 FBW1A_HUMAN (51-222): 1.02e-11: 69.1: 10.38		SMUF2_HUMAN (648-1024): 5.74e-160: 491: 26.22
+	Hs
		1336121 FBW1A_HUMAN (51-222): 1.02e-11: 69.1: 10.38		SMUF1_HUMAN (593-1024): 1.71e-157: 485: 23.71
+	Hs
		1065058 FBW1A_HUMAN (51-222): 1.02e-11: 69.1: 10.38		HERC3_HUMAN (317-460): 3.68e-11: 69.7: 10.88
+	Hs
		1065055 FBW1B_HUMAN (51-222): 2.76e-11: 67.6: 10.38		HERC3_HUMAN (317-460): 3.68e-11: 69.7: 10.88