HitPredict

Interactor 1: IKKA (Q60680)
Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA)
Gene: Chuk

Interactor 2: TRI44 (Q9QXA7)
Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7)
Gene: Trim44

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	15102471
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 745 Mm			1 346
+	Hs
		158392 IKKB_HUMAN (1-743): 0: 597: 49.93		RO52_HUMAN (163-346): 7.89e-47: 166: 20.53
+	Hs
		167580 IKKA_HUMAN (1-745): 0: 600: 95.44		TRI22_HUMAN (168-346): 1.55e-43: 158: 19.89
+	Hs
		167459 IKKA_HUMAN (1-745): 0: 600: 95.44		TRI27_HUMAN (152-345): 4.82e-41: 152: 14.50
+	Hs
		158386 IKKB_HUMAN (1-743): 0: 597: 49.93		TRI27_HUMAN (152-345): 4.82e-41: 152: 14.50
+	Hs
		585090 TBK1_HUMAN (15-679): 2.12e-122: 384: 19.52		RO52_HUMAN (163-346): 7.89e-47: 166: 20.53
+	Hs
		1050264 IKKE_HUMAN (15-730): 3.98e-121: 381: 19.50		TRIM6_HUMAN (124-345): 1.06e-46: 166: 19.74
+	Hs
		584875 CDK2_HUMAN (12-312): 3.75e-126: 379: 22.98		RO52_HUMAN (163-346): 7.89e-47: 166: 20.53
+	Hs
		537119 TBK1_HUMAN (15-679): 2.12e-122: 384: 19.52		TRI27_HUMAN (152-345): 4.82e-41: 152: 14.50
+	Hs
		1019379 TBK1_HUMAN (15-679): 2.12e-122: 384: 19.52		TRI26_HUMAN (170-343): 1.59e-40: 151: 17.22
+	Hs
		1190462 TBK1_HUMAN (15-679): 2.12e-122: 384: 19.52		TRI46_HUMAN (5-336): 1.88e-39: 150: 14.68
+	Hs
		1318703 TBK1_HUMAN (15-679): 2.12e-122: 384: 19.52		TRIM7_HUMAN (181-344): 1.56e-40: 150: 21.18
+	Hs
		536827 IKKE_HUMAN (15-730): 3.98e-121: 381: 19.50		TRI27_HUMAN (152-345): 4.82e-41: 152: 14.50
+	Hs
		1050263 IKKE_HUMAN (15-730): 3.98e-121: 381: 19.50		TRIM7_HUMAN (181-344): 1.56e-40: 150: 21.18
+	Mm
		1143608 TBK1_MOUSE (15-679): 8.43e-121: 380: 19.52		TRI27_MOUSE (152-345): 5.02e-41: 151: 14.00
+	Hs
		1354523 TBK1_HUMAN (15-679): 2.12e-122: 384: 19.52		TRI10_HUMAN (176-346): 1.12e-36: 139: 16.95
+	Hs
		262235 ULK1_HUMAN (7-221): 8.6e-30: 128: 34.06		RO52_HUMAN (163-346): 7.89e-47: 166: 20.53
+	Hs
		183318 ULK1_HUMAN (7-221): 8.6e-30: 128: 34.06		MEFV_HUMAN (142-346): 6.77e-42: 157: 12.26
+	Mm
		250797 ULK1_MOUSE (7-221): 2.6e-30: 130: 34.06		TRI27_MOUSE (152-345): 5.02e-41: 151: 14.00
+	Hs
		262230 ULK1_HUMAN (7-221): 8.6e-30: 128: 34.06		TRI27_HUMAN (152-345): 4.82e-41: 152: 14.50