Protein: MED30
Mediator of RNA polymerase II transcription subunit 30 (Mediator complex subunit 30) (TRAP/Mediator complex component TRAP25) (Thyroid hormone receptor-associated protein 6) (Thyroid hormone receptor-associated protein complex 25 kDa component) (Trap25)

Gene: MED30
Organism: Homo sapiens
Interactions: 87
UniProt ID: Q96HR3

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0003712 - transcription coregulator activity
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1393378

MED28
Mediator of RNA polymerase II transcription subunit 28

8

1

Small-scale

0.969

High

1149702

MED22
Mediator of RNA polymerase II transcription subunit 22

5

1

Small-scale

0.935

High

1393384

MED29
Mediator of RNA polymerase II transcription subunit 29

5

1

Small-scale

0.927

High

1393382

MED17
Mediator of RNA polymerase II transcription subunit 17

5

1

Small-scale

0.925

High

1393385

MED11
Mediator of RNA polymerase II transcription subunit 11

2

2

High-throughput

0.811

High

881585

CDK8
Cyclin-dependent kinase 8

9

3

Small-scale

0.753

High

49002

MED19
Mediator of RNA polymerase II transcription subunit 19

8

1

Small-scale

0.752

High

1372177

MED12
Mediator of RNA polymerase II transcription subunit 12

7

2

Small-scale

0.745

High

1393381

MED4
Mediator of RNA polymerase II transcription subunit 4

6

1

Small-scale

0.737

High

1393380

MED20
Mediator of RNA polymerase II transcription subunit 20

6

2

Small-scale

0.737

High

1393374

MED10
Mediator of RNA polymerase II transcription subunit 10

6

1

Small-scale

0.735

High

1151280

MED1
Mediator of RNA polymerase II transcription subunit 1

6

1

Small-scale

0.733

High

1393375

MED18
Mediator of RNA polymerase II transcription subunit 18

5

1

High-throughput

0.722

High

1393376

CDK19
Cyclin-dependent kinase 19

5

3

High-throughput

0.718

High

1108383

MED21
Mediator of RNA polymerase II transcription subunit 21

7

0

Small-scale

0.716

High

287810

MED6
Mediator of RNA polymerase II transcription subunit 6

5

1

Small-scale

0.716

High

219506

MED7
Mediator of RNA polymerase II transcription subunit 7

4

1

High-throughput

0.699

High

1241401

MED27
Mediator of RNA polymerase II transcription subunit 27

4

1

Small-scale

0.696

High

1391328

MED8
Mediator of RNA polymerase II transcription subunit 8

4

2

Small-scale

0.696

High

976131

RPB7
DNA-directed RNA polymerase II subunit RPB7

4

0

High-throughput

0.670

High

1393383

MED9
Mediator of RNA polymerase II transcription subunit 9

4

0

Small-scale

0.667

High

282409

MED24
Mediator of RNA polymerase II transcription subunit 24

3

1

Small-scale

0.667

High

1393386

MED13
Mediator of RNA polymerase II transcription subunit 13

3

2

Small-scale

0.662

High

1393387

MED23
Mediator of RNA polymerase II transcription subunit 23

3

1

Small-scale

0.656

High

336020

MED26
Mediator of RNA polymerase II transcription subunit 26

3

0

High-throughput

0.638

High

666886

CCNC
Cyclin-C

3

0

High-throughput

0.638

High

239606

MED14
Mediator of RNA polymerase II transcription subunit 14

2

2

High-throughput

0.628

High

1393390

MED31
Mediator of RNA polymerase II transcription subunit 31

2

1

High-throughput

0.628

High

1393370

MED30
Mediator of RNA polymerase II transcription subunit 30

1

1

Small-scale

0.618

High

188710

BIRC5
Baculoviral IAP repeat-containing protein 5

2

0

High-throughput

0.602

High

621934

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

2

0

High-throughput

0.602

High

667407

RPB1
DNA-directed RNA polymerase II subunit RPB1

2

0

Small-scale

0.585

High

912215

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

2

0

High-throughput

0.585

High

260302

BRD4
Bromodomain-containing protein 4

2

2

High-throughput

0.584

High

1393389

MED16
Mediator of RNA polymerase II transcription subunit 16

2

1

Small-scale

0.584

High

1393388

NP1L2
Nucleosome assembly protein 1-like 2

2

0

High-throughput

0.580

High

1393391

NDK7
Nucleoside diphosphate kinase homolog 7

2

0

High-throughput

0.580

High

274043

CREST
Calcium-responsive transactivator

1

1

High-throughput

0.541

High

1259058

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

1

2

High-throughput

0.536

High

1259268

MED25
Mediator of RNA polymerase II transcription subunit 25

1

1

High-throughput

0.536

High

1393372

MED15
Mediator of RNA polymerase II transcription subunit 15

1

2

High-throughput

0.536

High

316945

MTA2
Metastasis-associated protein MTA2

1

0

High-throughput

0.518

High

1393377

PHS2
Pterin-4-alpha-carbinolamine dehydratase 2

1

0

High-throughput

0.518

High

192843

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

High-throughput

0.513

High

621712

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.513

High

723050

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

0

High-throughput

0.513

High

787772

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

0

High-throughput

0.513

High

1243764

FXL19
F-box/LRR-repeat protein 19

1

0

High-throughput

0.513

High

1313030

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

1

0

High-throughput

0.513

High

1372263

H2B1H
Histone H2B type 1-H

1

0

High-throughput

0.493

High

843867

HD
Huntingtin

1

0

High-throughput

0.493

High

283532

TAD2A
Transcriptional adapter 2-alpha

1

1

High-throughput

0.479

High

674291

BRD2
Bromodomain-containing protein 2

1

2

High-throughput

0.479

High

1141261

BRD3
Bromodomain-containing protein 3

1

2

High-throughput

0.479

High

1295669

MD12L
Mediator of RNA polymerase II transcription subunit 12-like protein

1

2

High-throughput

0.479

High

343012

HERC2
E3 ubiquitin-protein ligase HERC2

1

0

High-throughput

0.458

High

372844

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

912102

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.458

High

920196

PLK1
Serine/threonine-protein kinase PLK1

1

0

High-throughput

0.458

High

959027

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

Small-scale

0.458

High

983686

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

0

High-throughput

0.458

High

1088970

TP53B
TP53-binding protein 1

1

0

High-throughput

0.458

High

1156816

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

1212021

ZC3HD
Zinc finger CCCH domain-containing protein 13

1

0

High-throughput

0.458

High

1257805

ACD11
Acyl-CoA dehydrogenase family member 11

1

0

High-throughput

0.458

High

1380083

FBXW7
F-box/WD repeat-containing protein 7

1

0

Small-scale

0.458

High

1393371

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

0

Small-scale

0.458

High

1393379

STN1
CST complex subunit STN1

1

0

High-throughput

0.458

High

396710

ESR1
Estrogen receptor

1

1

High-throughput

0.445

High

1227252

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.437

High

344287

PTBP3
Polypyrimidine tract-binding protein 3

1

0

High-throughput

0.426

High

1393373

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

76433

B4DUB1
cyclin-dependent kinase

1

3

High-throughput

0.407

High

169699

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

0

High-throughput

0.316

High

1313679

IFT20
Intraflagellar transport protein 20 homolog

2

0

High-throughput

0.316

High

950862

KR109
Keratin-associated protein 10-9

1

0

High-throughput

0.299

High

1338509

DOCK8
Dedicator of cytokinesis protein 8

1

0

High-throughput

0.299

High

405619

HRG
Histidine-rich glycoprotein

1

0

High-throughput

0.279

Low

1158822

CART

1

0

High-throughput

0.279

Low

1179837

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1393392

RPKL1
Ribosomal protein S6 kinase-like 1

1

0

High-throughput

0.279

Low

422881

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.261

Low

387550

APOA2
Apolipoprotein A-II

1

0

High-throughput

0.249

Low

646912

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.249

Low

1232004

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

1

0

High-throughput

0.249

Low

506020

GRL1A
DNA-directed RNA polymerase II subunit GRINL1A

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025