HitPredict

Interactor 1: SC6A4 (Q60857)
Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family 6 member 4)
Gene: Slc6a4

Interactor 2: MAGI2 (Q9WVQ1)
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Activin receptor-interacting protein 1) (Acvrip1) (Atrophin-1-interacting protein 1) (AIP-1) (Membrane-associated guanylate kinase inverted 2) (MAGI-2)
Gene: MAGI2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32581705
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0045202 - synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 630 Mm			1 1275
+	Hs
		808100 SC6A3_HUMAN (35-620): 0: 695: 48.56		NEDD4_HUMAN (88-421): 3.25e-60: 229: 19.46
+	Mm
		1141743 SC6A4_MOUSE (1-630): 0: 814: 100.00		MAGI3_MOUSE (18-392): 1.16e-21: 104: 11.66
+	Mm
		1141698 SC6A4_MOUSE (1-630): 0: 814: 100.00		GRIP1_MOUSE (13-547): 5.33e-21: 102: 12.77
+	Mm
		1141691 SC6A4_MOUSE (1-630): 0: 814: 100.00		DLG2_MOUSE (1108-1275): 2.79e-19: 96.3: 21.39
+	Mm
		1141564 SC6A4_MOUSE (1-630): 0: 814: 100.00		PTN13_MOUSE (843-1265): 5.14e-18: 92.9: 13.73
+	Mm
		936179 SC6A4_MOUSE (1-630): 0: 814: 100.00		DLG3_MOUSE (14-276): 1.21e-17: 90.9: 13.81
+	Mm
		1141587 SC6A4_MOUSE (1-630): 0: 814: 100.00		MAGI1_MOUSE (12-348): 1.26e-16: 87.9: 11.54
+	Mm
		1141556 SC6A4_MOUSE (1-630): 0: 814: 100.00		DLG4_MOUSE (370-517): 3.1e-16: 86.3: 15.54
+	Mm
		1141617 SC6A4_MOUSE (1-630): 0: 814: 100.00		DLG1_MOUSE (394-679): 3.6e-15: 83.1: 18.82
+	Mm
		1141563 SC6A4_MOUSE (1-630): 0: 814: 100.00		INADL_MOUSE (12-139): 5.32e-14: 79.4: 18.18
+	Mm
		1141705 SC6A4_MOUSE (1-630): 0: 814: 100.00		PARD3_MOUSE (1102-1253): 4.36e-13: 76.5: 20.71
+	Mm
		1142533 SC6A3_MOUSE (35-620): 0: 699: 47.97		INADL_MOUSE (12-139): 5.32e-14: 79.4: 18.18
+	Hs
		1252563 SC6A5_HUMAN (50-617): 0: 678: 40.50		LNX1_HUMAN (996-1255): 3.02e-15: 83.1: 11.79
+	Hs
		816325 S6A12_HUMAN (45-624): 0: 667: 42.47		SCRIB_HUMAN (5-786): 7.16e-13: 75.9: 8.25
+	Mm
		681265 SC6A1_MOUSE (33-621): 0: 650: 41.02		LNX2_MOUSE (1129-1256): 9.05e-16: 84.4: 23.08
+	Dm
		677694 DAT_DROME (53-620): 0: 659: 48.68		DLG1_DROME (1036-1243): 7.04e-12: 72.4: 20.46
+	Mm
		250599 SC6A1_MOUSE (33-621): 0: 650: 41.02		LNX1_MOUSE (16-98): 7.62e-10: 65.3: 26.74
+	Mm
		192599 SC6A6_MOUSE (59-617): 0: 626: 43.31		DLG4_MOUSE (370-517): 3.1e-16: 86.3: 15.54
+	Rn
		659340 SC6A9_RAT (49-617): 0: 624: 40.48		DLG4_RAT (370-517): 2.89e-16: 86.3: 15.54
+	Hs
		1252473 S6A15_HUMAN (67-596): 0: 558: 30.91		LNX1_HUMAN (996-1255): 3.02e-15: 83.1: 11.79