Protein: EXOC1
Exocyst complex component 1 (Exocyst complex component Sec3)

Gene: EXOC1
Organism: Homo sapiens
Interactions: 207
UniProt ID: Q9NV70

Gene Ontology (top 5):
GO:0000145 - exocyst
GO:0000281 - mitotic cytokinesis
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1396215

EXOC2
Exocyst complex component 2

6

2

Small-scale

0.948

High

1382593

EXOC4
Exocyst complex component 4

8

0

Small-scale

0.918

High

376003

RASK
GTPase KRas

2

5

High-throughput

0.754

High

1140151

IQCB1
IQ calmodulin-binding motif-containing protein 1

4

2

High-throughput

0.704

High

1350727

CCHCR
Coiled-coil alpha-helical rod protein 1

4

1

High-throughput

0.698

High

1419604

NUF2
Kinetochore protein Nuf2

4

2

High-throughput

0.697

High

252923

EXOC3
Exocyst complex component 3

4

1

High-throughput

0.697

High

1347251

EXOC6
Exocyst complex component 6

4

1

High-throughput

0.697

High

1450294

EXOC7
Exocyst complex component 7

4

1

High-throughput

0.697

High

1450296

EXC6B
Exocyst complex component 6B

4

1

High-throughput

0.697

High

1087037

KIF5A
Kinesin heavy chain isoform 5A

4

4

High-throughput

0.693

High

333405

SNAPN
SNARE-associated protein Snapin

5

0

High-throughput

0.687

High

1434686

RABE2
Rab GTPase-binding effector protein 2

3

1

High-throughput

0.675

High

1105668

GOGA4
Golgin subfamily A member 4

4

0

High-throughput

0.668

High

137279

EXOC5
Exocyst complex component 5

4

0

High-throughput

0.667

High

1093438

TRI32
E3 ubiquitin-protein ligase TRIM32

3

0

High-throughput

0.646

High

1315139

EXOC8
Exocyst complex component 8

3

0

High-throughput

0.646

High

1420540

TRIM9
E3 ubiquitin-protein ligase TRIM9

3

1

Small-scale

0.645

High

1389802

DTBP1
Dysbindin

3

0

High-throughput

0.638

High

1196328

GRAP1
GRIP1-associated protein 1

3

0

High-throughput

0.636

High

1255760

TRI67
Tripartite motif-containing protein 67

3

1

Small-scale

0.636

High

329986

ZWINT
Outer kinetochore KNL1 complex subunit ZWINT

3

0

High-throughput

0.634

High

1450009

BL1S4
Biogenesis of lysosome-related organelles complex 1 subunit 4

3

0

High-throughput

0.634

High

244190

KIF5C
Kinesin heavy chain isoform 5C

2

4

High-throughput

0.628

High

340249

PCNT
Pericentrin

2

3

High-throughput

0.628

High

705925

TNR8
Tumor necrosis factor receptor superfamily member 8

2

2

High-throughput

0.628

High

750013

KINH
Kinesin-1 heavy chain

2

4

High-throughput

0.628

High

771247

APJ
Apelin receptor

2

2

High-throughput

0.628

High

1092935

STRN3
Striatin-3

2

4

High-throughput

0.628

High

1121987

ARHG7
Rho guanine nucleotide exchange factor 7

2

2

High-throughput

0.628

High

1138094

TNIP1
TNFAIP3-interacting protein 1

2

3

High-throughput

0.628

High

1144885

RABE1
Rab GTPase-binding effector protein 1

2

1

High-throughput

0.628

High

1156604

CCDC6
Coiled-coil domain-containing protein 6

2

1

High-throughput

0.628

High

1450282

VPS51
Vacuolar protein sorting-associated protein 51 homolog

2

3

High-throughput

0.628

High

1450298

GIT1
ARF GTPase-activating protein GIT1

2

3

High-throughput

0.628

High

1439062

NCK5L
Nck-associated protein 5-like

3

0

High-throughput

0.622

High

374231

RASN
GTPase NRas

1

6

High-throughput

0.618

High

374967

RASH
GTPase HRas

1

5

High-throughput

0.618

High

539907

RALB
Ras-related protein Ral-B

1

6

High-throughput

0.618

High

1312337

MIRO1
Mitochondrial Rho GTPase 1

1

1

High-throughput

0.618

High

343485

SNP29
Synaptosomal-associated protein 29

2

2

High-throughput

0.611

High

1413134

THAP7
THAP domain-containing protein 7

3

2

High-throughput

0.609

High

164111

NDC80
Kinetochore protein NDC80 homolog

2

0

High-throughput

0.602

High

192966

CLOCK
Circadian locomoter output cycles protein kaput

2

0

High-throughput

0.602

High

699580

IL1R2
Interleukin-1 receptor type 2

2

0

High-throughput

0.602

High

1094636

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

2

0

High-throughput

0.602

High

1211902

FKB15
FK506-binding protein 15

2

0

High-throughput

0.602

High

1217288

VPS53
Vacuolar protein sorting-associated protein 53 homolog

2

0

High-throughput

0.602

High

1239958

CAVN1
Caveolae-associated protein 1

2

0

High-throughput

0.602

High

1246506

BL1S2
Biogenesis of lysosome-related organelles complex 1 subunit 2

2

0

High-throughput

0.602

High

1247527

POTEE
POTE ankyrin domain family member E

2

0

High-throughput

0.602

High

1348340

GOGA5
Golgin subfamily A member 5

2

0

High-throughput

0.602

High

1389081

THA11
THAP domain-containing protein 11

2

0

High-throughput

0.602

High

1394937

VPS50
Syndetin

2

0

High-throughput

0.602

High

1411928

SIKE1
Suppressor of IKBKE 1

2

0

High-throughput

0.602

High

1445775

TUFT1
Tuftelin

2

0

High-throughput

0.602

High

1450284

RABX5
Rab5 GDP/GTP exchange factor

2

0

High-throughput

0.602

High

1450285

TSKS
Testis-specific serine kinase substrate

2

0

High-throughput

0.602

High

1450297

COG6
Conserved oligomeric Golgi complex subunit 6

2

0

High-throughput

0.602

High

1101680

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

2

2

High-throughput

0.601

High

1252990

BAKOR
Beclin 1-associated autophagy-related key regulator

2

0

Small-scale

0.593

High

299583

TRIO
Triple functional domain protein

2

3

High-throughput

0.590

High

1040388

DYST
Dystonin

2

3

High-throughput

0.590

High

1117510

SPTN1
Spectrin alpha chain, non-erythrocytic 1

2

2

High-throughput

0.590

High

1450293

MACF1
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5

2

3

High-throughput

0.590

High

976599

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.586

High

269619

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

2

1

High-throughput

0.576

High

1191493

GRDN
Girdin

2

2

High-throughput

0.576

High

388314

GLPA
Glycophorin-A

2

0

High-throughput

0.576

High

1122450

GIT2
ARF GTPase-activating protein GIT2

2

4

High-throughput

0.574

High

1384457

PF21A
PHD finger protein 21A

2

1

High-throughput

0.574

High

239431

3BP5
SH3 domain-binding protein 5

2

0

High-throughput

0.565

High

1207973

COL12
Collectin-12

2

0

High-throughput

0.565

High

1421055

CE295
Centrosomal protein of 295 kDa

2

0

High-throughput

0.565

High

1435916

CCSE2
Serine-rich coiled-coil domain-containing protein 2

2

0

High-throughput

0.565

High

1448490

DISC1
Disrupted in schizophrenia 1 protein

2

0

High-throughput

0.565

High

373279

MYC
Myc proto-oncogene protein

2

0

High-throughput

0.559

High

1201163

CCD93
Coiled-coil domain-containing protein 93

2

0

High-throughput

0.551

High

1351599

MIPT3
TRAF3-interacting protein 1

2

0

High-throughput

0.551

High

1404443

CDC5L
Cell division cycle 5-like protein

2

0

High-throughput

0.551

High

262322

SCN2B
Sodium channel regulatory subunit beta-2

2

0

High-throughput

0.547

High

1154179

ITSN1
Intersectin-1

1

3

High-throughput

0.541

High

182800

GP182
G-protein coupled receptor 182

1

4

High-throughput

0.536

High

228637

STRN
Striatin

1

3

High-throughput

0.536

High

665327

EDNRB
Endothelin receptor type B

1

2

High-throughput

0.536

High

957027

CXCR4
C-X-C chemokine receptor type 4

1

3

High-throughput

0.536

High

1290446

EX3L1
Exocyst complex component 3-like protein

1

1

High-throughput

0.536

High

1450279

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

1

1

High-throughput

0.536

High

1365940

RUBIC
Run domain Beclin-1-interacting and cysteine-rich domain-containing protein

1

0

Small-scale

0.529

High

445270

S10A6
Protein S100-A6

1

0

High-throughput

0.513

High

914355

EFNA4
Ephrin-A4

1

0

High-throughput

0.513

High

1105879

TMED1
Transmembrane emp24 domain-containing protein 1

1

0

High-throughput

0.513

High

1258694

IKIP
Inhibitor of nuclear factor kappa-B kinase-interacting protein

1

0

High-throughput

0.513

High

1430978

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.513

High

1446519

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.513

High

1450286

CC018
Uncharacterized protein C3orf18

1

0

High-throughput

0.513

High

1450295

TN13B
Tumor necrosis factor ligand superfamily member 13B

1

0

High-throughput

0.513

High

869797

MTR1A
Melatonin receptor type 1A

1

1

High-throughput

0.508

High

617255

ATF4
Cyclic AMP-dependent transcription factor ATF-4

1

0

High-throughput

0.493

High

69410

WASH1
WASH complex subunit 1

1

0

Small-scale

0.484

High

1351992

RBCC1
RB1-inducible coiled-coil protein 1

1

3

Small-scale

0.481

High

1227553

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.479

High

1315409

TEFF1
Tomoregulin-1

1

1

High-throughput

0.479

High

1434019

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

791766

SYUA
Alpha-synuclein

1

0

High-throughput

0.460

High

1311654

KIBRA
Protein KIBRA

1

0

Small-scale

0.460

High

243080

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

346400

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

390781

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.458

High

412686

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

537987

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

774664

BASI
Basigin

1

0

High-throughput

0.458

High

850907

KI2S2
Killer cell immunoglobulin-like receptor 2DS2

1

0

High-throughput

0.458

High

1141970

EEA1
Early endosome antigen 1

1

0

High-throughput

0.458

High

1360828

ASB11
Ankyrin repeat and SOCS box protein 11

1

0

High-throughput

0.458

High

1393747

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1447772

DBLOH
Diablo IAP-binding mitochondrial protein

1

0

High-throughput

0.458

High

1450277

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1450278

PD1L1
Programmed cell death 1 ligand 1

1

0

High-throughput

0.458

High

1450280

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1450291

CAH14
Carbonic anhydrase 14

1

0

High-throughput

0.458

High

164829

UN13B
Protein unc-13 homolog B

1

1

High-throughput

0.457

High

176623

KIF3B
Kinesin-like protein KIF3B

1

4

High-throughput

0.457

High

1134747

NUMA1
Nuclear mitotic apparatus protein 1

1

2

High-throughput

0.457

High

1211655

FBP1L
Formin-binding protein 1-like

1

2

High-throughput

0.457

High

1278699

KI21A
Kinesin-like protein KIF21A

1

4

High-throughput

0.457

High

1279853

SRGP1
SLIT-ROBO Rho GTPase-activating protein 1

1

1

High-throughput

0.457

High

1338583

SYNE1
Nesprin-1

1

4

High-throughput

0.457

High

1360184

RUFY2
RUN and FYVE domain-containing protein 2

1

3

High-throughput

0.457

High

1360681

SYNE2
Nesprin-2

1

3

High-throughput

0.457

High

1361488

IFT81
Intraflagellar transport protein 81 homolog

1

2

High-throughput

0.457

High

1402914

CK5P2
CDK5 regulatory subunit-associated protein 2

1

2

High-throughput

0.457

High

1448058

ARHG4
Rho guanine nucleotide exchange factor 4

1

3

High-throughput

0.457

High

1450287

ASAP1
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1

1

1

High-throughput

0.457

High

1450292

COG5
Conserved oligomeric Golgi complex subunit 5

1

1

High-throughput

0.457

High

171593

S27A2
Long-chain fatty acid transport protein 2

1

1

High-throughput

0.445

High

616814

SDC1
Syndecan-1

1

1

High-throughput

0.445

High

638536

FPR1
fMet-Leu-Phe receptor

1

3

High-throughput

0.445

High

683349

TNR5
Tumor necrosis factor receptor superfamily member 5

1

1

High-throughput

0.445

High

726700

SDC4
Syndecan-4

1

1

High-throughput

0.445

High

872035

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

1

2

High-throughput

0.445

High

1006176

PI42B
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta

1

2

High-throughput

0.445

High

1240970

S27A4
Long-chain fatty acid transport protein 4

1

1

High-throughput

0.445

High

1349226

PI42C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

1

2

High-throughput

0.445

High

1448641

STRN4
Striatin-4

1

2

High-throughput

0.445

High

1276110

KANL1
KAT8 regulatory NSL complex subunit 1

1

1

High-throughput

0.439

High

217334

PROM1
Prominin-1

1

0

High-throughput

0.438

High

317933

LTN1
E3 ubiquitin-protein ligase listerin

1

0

High-throughput

0.438

High

702522

ACADL
Long-chain specific acyl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.438

High

773793

ACTN2
Alpha-actinin-2

1

0

High-throughput

0.438

High

923643

TTC3
E3 ubiquitin-protein ligase TTC3

1

0

High-throughput

0.438

High

1065772

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

0

High-throughput

0.438

High

1123449

ICT1
Large ribosomal subunit protein mL62

1

0

High-throughput

0.438

High

1128383

ITPR2
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2

1

0

High-throughput

0.438

High

1193483

CCD14
Coiled-coil domain-containing protein 14

1

0

High-throughput

0.438

High

1338119

NAV1
Neuron navigator 1

1

0

High-throughput

0.438

High

1395218

CHAP1
Chromosome alignment-maintaining phosphoprotein 1

1

0

High-throughput

0.438

High

1401302

SNX18
Sorting nexin-18

1

0

High-throughput

0.438

High

1431818

EPC1
Enhancer of polycomb homolog 1

1

0

High-throughput

0.438

High

1450276

TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

1

0

High-throughput

0.438

High

1450289

CAPS1
Calcium-dependent secretion activator 1

1

0

High-throughput

0.438

High

50711

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.426

High

716139

AL4A1
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

1

0

High-throughput

0.426

High

880714

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.426

High

1139400

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

0

High-throughput

0.426

High

1208995

RBG1L
Rab GTPase-activating protein 1-like

1

0

High-throughput

0.426

High

1404964

S1PR3
Sphingosine 1-phosphate receptor 3

1

0

High-throughput

0.426

High

1432063

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

0

High-throughput

0.426

High

1436001

PACC1
Proton-activated chloride channel

1

0

High-throughput

0.426

High

1439044

CWC22
Pre-mRNA-splicing factor CWC22 homolog

1

0

High-throughput

0.426

High

1450281

SEC63
Translocation protein SEC63 homolog

1

0

High-throughput

0.426

High

1450290

FZD10
Frizzled-10

1

0

High-throughput

0.426

High

1450300

NOC2L
Nucleolar complex protein 2 homolog

1

0

High-throughput

0.426

High

47899

KAL1L
KAT8 regulatory NSL complex subunit 1-like protein

1

1

High-throughput

0.417

High

1280133

THAP5
THAP domain-containing protein 5

1

2

High-throughput

0.417

High

1315522

CC170
Coiled-coil domain-containing protein 170

1

2

High-throughput

0.417

High

1324488

AN36B
Ankyrin repeat domain-containing protein 36B

1

1

High-throughput

0.417

High

1276167

NUP54
Nucleoporin p54

5

0

High-throughput

0.374

High

1410533

KXDL1
KxDL motif-containing protein 1

4

0

High-throughput

0.359

High

1200077

EIPR1
EARP and GARP complex-interacting protein 1

3

0

High-throughput

0.352

High

430415

JUN
Transcription factor Jun

2

0

High-throughput

0.328

High

85316

RBG10
Rab GTPase-activating protein 1-like, isoform 10

2

0

High-throughput

0.318

High

1178897

CF184
Cilia- and flagella-associated protein 184

2

0

High-throughput

0.313

High

1316930

FAM9C
Protein FAM9C

2

0

High-throughput

0.313

High

1439263

RESF1
Retroelement silencing factor 1

2

0

High-throughput

0.307

High

246985

KDM1A
Lysine-specific histone demethylase 1A

2

0

High-throughput

0.300

High

1293853

SFR1
Swi5-dependent recombination DNA repair protein 1 homolog

2

0

High-throughput

0.300

High

1450275

SYBU
Syntabulin

2

0

High-throughput

0.300

High

1450299

LC7L2
Putative RNA-binding protein Luc7-like 2

2

0

High-throughput

0.300

High

1111307

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.279

Low

1211684

CC122
Coiled-coil domain-containing protein 122

1

0

High-throughput

0.279

Low

589827

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

696646

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

769314

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1367393

ESR2
Estrogen receptor beta

1

0

High-throughput

0.249

Low

1450288

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

Small-scale

0.249

Low

183305

LAMA5
Laminin subunit alpha-5

1

0

High-throughput

0.238

Low

936532

AF10
Protein AF-10

1

0

High-throughput

0.238

Low

1314917

CC146
Coiled-coil domain-containing protein 146

1

0

High-throughput

0.238

Low

1346705

CA216
UPF0500 protein C1orf216

1

0

High-throughput

0.238

Low

1450283

TEKT2
Tektin-2

1

0

High-throughput

0.238

Low

223900

NDUA2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2

1

0

High-throughput

0.232

Low

1152877

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

0

High-throughput

0.232

Low

1167120

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

0

High-throughput

0.232

Low

1324252

ARM10
Armadillo repeat-containing protein 10

1

0

High-throughput

0.232

Low

1351649

TCP1L
T-complex protein 10A homolog 1

1

0

High-throughput

0.232

Low

1450274

IFT57
Intraflagellar transport protein 57 homolog

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025