Interactor 1: I17RA (Q60943)
Interleukin-17 receptor A (IL-17 receptor A) (IL-17RA) (CD antigen CD217)
Gene: Il17ra

Interactor 2: CIKS (Q8N7N6)
E3 ubiquitin ligase TRAF3IP2 (EC 2.3.2.27) (Adapter protein CIKS) (Connection to IKK and SAPK/JNK) (E3 ubiquitin-protein ligase CIKS) (Nuclear factor NF-kappa-B activator 1) (ACT1) (TRAF3-interacting protein 2)
Gene: Traf3ip2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 1.00 0.806

The method score is based on:

Property Details
Experiments 28219902, 22045852
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains SEFIR~SEFIR
Common GO terms GO:0005102 - signaling receptor binding
GO:0006954 - inflammatory response
GO:0038173 - interleukin-17A-mediated signaling pathway
GO:0071345 - cellular response to cytokine stimulus
GO:0072538 - T-helper 17 type immune response
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 864
Mm

1 555
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024