Protein: PLXB2
Plexin-B2 (MM1)

Gene: PLXB2, PLXNB2
Organism: Homo sapiens
Interactions: 155
UniProt ID: O15031

Gene Ontology (top 5):
GO:0001843 - neural tube closure
GO:0001932 - regulation of protein phosphorylation
GO:0002116 - semaphorin receptor complex
GO:0005886 - plasma membrane
GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

120208

RHOD
Rho-related GTP-binding protein RhoD

4

20

High-throughput

0.895

High

165231

RND1
Rho-related GTP-binding protein Rho6

2

20

Small-scale

0.793

High

165172

RND2
Rho-related GTP-binding protein RhoN

2

20

Small-scale

0.789

High

165183

RND3
Rho-related GTP-binding protein RhoE

2

20

Small-scale

0.789

High

165213

BTNL8
Butyrophilin-like protein 8

2

10

High-throughput

0.789

High

165243

SEM4C
Semaphorin-4C

1

20

High-throughput

0.691

High

165267

BTNL2
Butyrophilin-like protein 2

1

15

High-throughput

0.691

High

165193

LMAN2
Vesicular integral-membrane protein VIP36

3

1

High-throughput

0.667

High

165196

PTC1
Protein patched homolog 1

3

10

High-throughput

0.667

High

165221

LYPD6
Ly6/PLAUR domain-containing protein 6

3

1

High-throughput

0.667

High

165147

MET
Hepatocyte growth factor receptor

1

19

Small-scale

0.665

High

165192

RON
Macrophage-stimulating protein receptor

1

20

Small-scale

0.665

High

165250

SEM4A
Semaphorin-4A

1

20

Small-scale

0.647

High

165204

NTRK3
NT-3 growth factor receptor

1

12

High-throughput

0.646

High

165122

ARHGB
Rho guanine nucleotide exchange factor 11

2

20

Small-scale

0.640

High

165176

DEF1
Neutrophil defensin 1

2

5

High-throughput

0.628

High

165214

BTNL3
Butyrophilin-like protein 3

1

10

High-throughput

0.618

High

165135

RASK
GTPase KRas

1

20

High-throughput

0.618

High

165138

NTRK1
High affinity nerve growth factor receptor

1

14

High-throughput

0.618

High

165146

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.618

High

165155

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

165157

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.618

High

165166

MUC18
Cell surface glycoprotein MUC18

1

5

High-throughput

0.618

High

165170

RAB5C
Ras-related protein Rab-5C

1

4

High-throughput

0.618

High

165171

RAB9A
Ras-related protein Rab-9A

1

8

High-throughput

0.618

High

165179

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

165180

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.618

High

165181

RAB2A
Ras-related protein Rab-2A

1

3

High-throughput

0.618

High

165182

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

165185

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

165187

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

165189

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.618

High

165201

RAB35
Ras-related protein Rab-35

1

4

High-throughput

0.618

High

165202

TLR1
Toll-like receptor 1

1

1

High-throughput

0.618

High

165203

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.618

High

165218

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.618

High

165251

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.618

High

165255

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

165137

TRGV3
T cell receptor gamma variable 3

1

1

High-throughput

0.575

High

165191

DEF5
Defensin alpha 5

2

5

High-throughput

0.574

High

165229

SIA8D
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

2

6

High-throughput

0.574

High

165249

TMX1
Thioredoxin-related transmembrane protein 1

2

11

High-throughput

0.574

High

165234

LRC59
Leucine-rich repeat-containing protein 59

1

1

High-throughput

0.553

High

82355

IGLL5
Immunoglobulin lambda-like polypeptide 5

1

8

High-throughput

0.536

High

165129

ECEL1
Endothelin-converting enzyme-like 1

1

2

High-throughput

0.536

High

165148

LEG1
Galectin-1

1

8

High-throughput

0.536

High

165158

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

8

High-throughput

0.536

High

165162

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

20

High-throughput

0.536

High

165173

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

7

High-throughput

0.536

High

165190

IL5RA
Interleukin-5 receptor subunit alpha

1

12

High-throughput

0.536

High

165205

PTPRO
Receptor-type tyrosine-protein phosphatase O

1

17

High-throughput

0.536

High

165211

I27RA
Interleukin-27 receptor subunit alpha

1

8

High-throughput

0.536

High

165216

CDHR3
Cadherin-related family member 3

1

15

High-throughput

0.536

High

165230

CLC2B
C-type lectin domain family 2 member B

1

20

High-throughput

0.536

High

165232

GGH
Gamma-glutamyl hydrolase

1

4

High-throughput

0.536

High

165233

T106A
Transmembrane protein 106A

1

9

High-throughput

0.536

High

165235

ASIC4
Acid-sensing ion channel 4

1

4

High-throughput

0.536

High

165242

CNTP3
Contactin-associated protein-like 3

1

14

High-throughput

0.536

High

165269

ADA21
Disintegrin and metalloproteinase domain-containing protein 21

1

5

High-throughput

0.536

High

165178

SC61B
Protein transport protein Sec61 subunit beta

2

1

High-throughput

0.533

High

165160

PTN
Pleiotrophin

1

0

High-throughput

0.518

High

165163

DPP4
Dipeptidyl peptidase 4

1

2

High-throughput

0.515

High

165219

TM11B
Transmembrane protease serine 11B

1

20

High-throughput

0.515

High

165259

TMPS4
Transmembrane protease serine 4

1

20

High-throughput

0.515

High

90044

D6RAP2
Toll like receptor 1

1

6

High-throughput

0.514

High

165128

S22A3
Solute carrier family 22 member 3

1

0

High-throughput

0.513

High

165133

BY55
CD160 antigen

1

0

High-throughput

0.513

High

165136

APOA2
Apolipoprotein A-II

1

0

High-throughput

0.513

High

165156

TSHR
Thyrotropin receptor

1

0

High-throughput

0.513

High

165222

I17RC
Interleukin-17 receptor C

1

0

High-throughput

0.513

High

165225

ARRD4
Arrestin domain-containing protein 4

1

0

High-throughput

0.513

High

165142

INSR
Insulin receptor

1

19

High-throughput

0.500

High

165145

IGF1R
Insulin-like growth factor 1 receptor

1

18

High-throughput

0.500

High

165127

SG2A1
Mammaglobin-B

1

5

High-throughput

0.489

High

165130

LY86
Lymphocyte antigen 86

1

6

High-throughput

0.489

High

165131

QORL1
Quinone oxidoreductase-like protein 1

1

1

High-throughput

0.489

High

165132

SG1D1
Secretoglobin family 1D member 1

1

6

High-throughput

0.489

High

165139

REL1
Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]

1

2

High-throughput

0.489

High

165151

PSPC
Surfactant protein C

1

8

High-throughput

0.489

High

165168

DNSL1
Deoxyribonuclease-1-like 1

1

5

High-throughput

0.489

High

165174

EP3B
Epididymal secretory protein E3-beta

1

6

High-throughput

0.489

High

165175

TMPS3
Transmembrane protease serine 3

1

19

High-throughput

0.489

High

165206

CL12B
C-type lectin domain family 12 member B

1

20

High-throughput

0.489

High

165207

DB135
Beta-defensin 135

1

3

High-throughput

0.489

High

165208

MPPE1
Metallophosphoesterase 1

1

2

High-throughput

0.489

High

165210

BRID5
BRICHOS domain-containing protein 5

1

6

High-throughput

0.489

High

165224

RN149
E3 ubiquitin-protein ligase RNF149

1

4

High-throughput

0.489

High

165227

CA054
Uncharacterized protein C1orf54

1

10

High-throughput

0.489

High

165228

PATE1
Prostate and testis expressed protein 1

1

1

High-throughput

0.489

High

165236

ZDH12
Palmitoyltransferase ZDHHC12

1

3

High-throughput

0.489

High

165238

LCFC1
Sperm-egg fusion protein LLCFC1

1

2

High-throughput

0.489

High

165246

CST11
Cystatin-11

1

6

High-throughput

0.489

High

165256

SDF2L
Stromal cell-derived factor 2-like protein 1

1

9

High-throughput

0.489

High

165260

CBLN4
Cerebellin-4

1

12

High-throughput

0.489

High

165268

FBX2
F-box only protein 2

1

17

High-throughput

0.489

High

165165

HMOX2
Heme oxygenase 2

1

0

High-throughput

0.486

High

165123

TMPS2
Transmembrane protease serine 2

1

19

High-throughput

0.479

High

165124

TGON2
Trans-Golgi network integral membrane protein 2

1

16

High-throughput

0.479

High

165134

EGFR
Epidermal growth factor receptor

1

18

High-throughput

0.479

High

165143

LYN
Tyrosine-protein kinase Lyn

1

16

High-throughput

0.479

High

165144

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

15

High-throughput

0.479

High

165150

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

165153

LAMP2
Lysosome-associated membrane glycoprotein 2

1

2

High-throughput

0.479

High

165154

HLAE
HLA class I histocompatibility antigen, alpha chain E

1

8

High-throughput

0.479

High

165159

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

6

Small-scale

0.479

High

165164

MARCS
Myristoylated alanine-rich C-kinase substrate

1

3

High-throughput

0.479

High

165184

ARF6
ADP-ribosylation factor 6

1

4

High-throughput

0.479

High

165186

GRB2
Growth factor receptor-bound protein 2

1

20

Small-scale

0.479

High

165195

CUL3
Cullin-3

1

1

High-throughput

0.479

High

165197

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

11

High-throughput

0.479

High

165200

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

1

17

High-throughput

0.479

High

165212

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

165215

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

165237

DNJC1
DnaJ homolog subfamily C member 1

1

10

High-throughput

0.479

High

165245

CCDC8
Coiled-coil domain-containing protein 8

1

1

High-throughput

0.479

High

165252

PKHA4
Pleckstrin homology domain-containing family A member 4

1

7

High-throughput

0.479

High

165261

T106B
Transmembrane protein 106B

1

9

High-throughput

0.479

High

165264

ARHGC
Rho guanine nucleotide exchange factor 12

1

16

Small-scale

0.479

High

165270

LAMP3
Lysosome-associated membrane glycoprotein 3

1

2

High-throughput

0.479

High

165217

CENPU
Centromere protein U

1

1

High-throughput

0.464

High

165152

CP2C9
Cytochrome P450 2C9

1

0

High-throughput

0.458

High

165209

PVRIG
Transmembrane protein PVRIG

1

0

High-throughput

0.458

High

165254

SIAE
Sialate O-acetylesterase

1

0

High-throughput

0.458

High

165161

CD9
CD9 antigen

1

2

High-throughput

0.445

High

165177

CD81
CD81 antigen

1

2

High-throughput

0.445

High

165167

SSRA
Translocon-associated protein subunit alpha

1

1

High-throughput

0.437

High

165169

EMD
Emerin

1

1

High-throughput

0.437

High

165194

SMAD4
Mothers against decapentaplegic homolog 4

1

2

High-throughput

0.437

High

165223

DHB11
Estradiol 17-beta-dehydrogenase 11

1

1

High-throughput

0.437

High

165239

SEC62
Translocation protein SEC62

1

2

High-throughput

0.437

High

165247

DJC25
DnaJ homolog subfamily C member 25

1

10

High-throughput

0.437

High

165248

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

1

High-throughput

0.437

High

165253

TMT1A
Thiol S-methyltransferase TMT1A

1

1

High-throughput

0.437

High

165258

FBX6
F-box only protein 6

1

17

High-throughput

0.437

High

165262

OTULL
Inactive ubiquitin thioesterase OTULINL

1

1

High-throughput

0.437

High

165263

ELOV5
Very long chain fatty acid elongase 5

1

1

High-throughput

0.437

High

165265

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.437

High

165149

ZTRF1
Zinc finger TRAF-type-containing protein 1

1

1

High-throughput

0.407

High

63912

C2C4B
C2 calcium-dependent domain-containing protein 4B

1

0

High-throughput

0.279

Low

165199

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.279

Low

165226

TMED6
Transmembrane emp24 domain-containing protein 6

1

0

High-throughput

0.279

Low

165266

SRGEF
Secretion-regulating guanine nucleotide exchange factor

1

0

High-throughput

0.279

Low

165271

SPCS1
Signal peptidase complex subunit 1

1

0

High-throughput

0.279

Low

165126

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.265

Low

163663

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

0

High-throughput

0.249

Low

165125

ZC3H1
Zinc finger C3H1 domain-containing protein

1

0

High-throughput

0.249

Low

165140

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.249

Low

165141

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low

165188

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

165198

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

0

High-throughput

0.249

Low

165220

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.249

Low

165240

TBCD
Tubulin-specific chaperone D

1

0

High-throughput

0.249

Low

165241

DERL1
Derlin-1

1

0

High-throughput

0.249

Low

165244

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.249

Low

165257

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024