Interactor 1: RBBP4 (Q60972)
Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48)
Gene: RBBP4

Interactor 2: SUZ12 (Q80U70)
Polycomb protein Suz12 (Suppressor of zeste 12 protein homolog)
Gene: SUZ12

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 25680957, 22438827
Identification Methods proximity labelling technology, affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CAF1C_H4-bd~VEFS-Box, VEFS-Box~WD40
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0035098 - ESC/E(Z) complex
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 425
Mm

1 741
+ Hs
+ Hs
+ Mm
+ Dm
+ At
+ At

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Last updated: 15 Jul 2024