Protein: ESF1
ESF1 homolog (ABT1-associated protein)

Gene: ESF1
Organism: Homo sapiens
Interactions: 151
UniProt ID: Q9H501

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005615 - extracellular space
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0006364 - rRNA processing

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

373145

MYC
Myc proto-oncogene protein

3

1

High-throughput

0.640

High

447441

NPM
Nucleophosmin

3

0

High-throughput

0.622

High

998026

CSK21
Casein kinase II subunit alpha

2

2

High-throughput

0.611

High

1434468

ABT1
Activator of basal transcription 1

2

1

High-throughput

0.601

High

644053

FBRL
rRNA 2'-O-methyltransferase fibrillarin

2

1

High-throughput

0.584

High

396940

ESR1
Estrogen receptor

2

3

High-throughput

0.571

High

977372

RS4X
Small ribosomal subunit protein eS4, X isoform

2

2

High-throughput

0.571

High

1429615

NAT10
RNA cytidine acetyltransferase

2

1

High-throughput

0.571

High

979235

RS6
Small ribosomal subunit protein eS6

2

0

High-throughput

0.559

High

1346928

SNIP1
Smad nuclear-interacting protein 1

2

0

High-throughput

0.547

High

969443

RS8
Small ribosomal subunit protein eS8

1

1

High-throughput

0.536

High

973589

RS11
Small ribosomal subunit protein uS17

1

2

High-throughput

0.536

High

1337490

NGDN
Neuroguidin

1

1

High-throughput

0.536

High

1430384

DDX47
Probable ATP-dependent RNA helicase DDX47

1

5

High-throughput

0.536

High

1433774

SENP3
Sentrin-specific protease 3

1

1

High-throughput

0.536

High

1434457

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

1

High-throughput

0.536

High

1372305

H2B1H
Histone H2B type 1-H

1

2

High-throughput

0.515

High

155354

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

0

High-throughput

0.513

High

277955

SH3L1
Adapter SH3BGRL

1

0

High-throughput

0.513

High

694396

CO8A1
Collagen alpha-1(VIII) chain

1

0

High-throughput

0.513

High

783171

ARL3
ADP-ribosylation factor-like protein 3

1

0

High-throughput

0.513

High

905142

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.513

High

911378

IMA5
Importin subunit alpha-5

1

0

High-throughput

0.513

High

948588

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.513

High

1027754

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

0

High-throughput

0.513

High

1117669

NOG2
Nucleolar GTP-binding protein 2

1

0

High-throughput

0.513

High

1127490

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.513

High

1142817

PEA15
Astrocytic phosphoprotein PEA-15

1

0

High-throughput

0.513

High

1145370

RNPS1
RNA-binding protein with serine-rich domain 1

1

0

High-throughput

0.513

High

1368800

EZH1
Histone-lysine N-methyltransferase EZH1

1

0

High-throughput

0.513

High

1411877

TCAL7
Transcription elongation factor A protein-like 7

1

0

High-throughput

0.513

High

1434467

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

0

High-throughput

0.513

High

1434470

FBX7
F-box only protein 7

1

0

High-throughput

0.513

High

1413557

H2AJ
Histone H2A.J

1

2

High-throughput

0.489

High

1434463

ATS1
A disintegrin and metalloproteinase with thrombospondin motifs 1

1

1

High-throughput

0.489

High

141107

NOP56
Nucleolar protein 56

1

2

High-throughput

0.479

High

289696

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

1

High-throughput

0.479

High

404422

GCR
Glucocorticoid receptor

1

3

High-throughput

0.479

High

406638

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

636148

CD11B
Cyclin-dependent kinase 11B

1

1

High-throughput

0.479

High

652576

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

3

High-throughput

0.479

High

862459

YAP1
Transcriptional coactivator YAP1

1

1

High-throughput

0.479

High

881606

CDK8
Cyclin-dependent kinase 8

1

1

High-throughput

0.479

High

883688

CENPA
Histone H3-like centromeric protein A

1

2

High-throughput

0.479

High

981094

H2B1C
Histone H2B type 1-C/E/F/G/I

1

2

High-throughput

0.479

High

984983

RL31
Large ribosomal subunit protein eL31

1

1

High-throughput

0.479

High

995270

CSK2B
Casein kinase II subunit beta

1

1

High-throughput

0.479

High

1097559

CBX3
Chromobox protein homolog 3

1

1

High-throughput

0.479

High

1258943

H32
Histone H3.2

1

2

Small-scale

0.479

High

1329869

SIR6
NAD-dependent protein deacylase sirtuin-6

1

1

High-throughput

0.479

High

1367273

ESR2
Estrogen receptor beta

1

3

High-throughput

0.479

High

1368618

KAT6A
Histone acetyltransferase KAT6A

1

1

High-throughput

0.479

High

1434454

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

1

High-throughput

0.479

High

191090

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

223330

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

254429

CC14B
Dual specificity protein phosphatase CDC14B

1

0

High-throughput

0.458

High

260453

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

302639

RNF8
E3 ubiquitin-protein ligase RNF8

1

0

Small-scale

0.458

High

346326

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

370779

FOS
Protein c-Fos

1

0

High-throughput

0.458

High

487754

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

558403

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

569138

T2FB
General transcription factor IIF subunit 2

1

0

High-throughput

0.458

High

657685

GCSP
Glycine dehydrogenase

1

0

High-throughput

0.458

High

769173

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

800102

COIL
Coilin

1

0

High-throughput

0.458

High

807583

IF4A3
Eukaryotic initiation factor 4A-III

1

0

High-throughput

0.458

High

886322

ARL4D
ADP-ribosylation factor-like protein 4D

1

0

High-throughput

0.458

High

937910

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

982825

RS24
Small ribosomal subunit protein eS24

1

0

High-throughput

0.458

High

995820

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.458

High

1045768

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1096817

RFA4
Replication protein A 30 kDa subunit

1

0

High-throughput

0.458

High

1146826

PCBP1
Poly(rC)-binding protein 1

1

0

High-throughput

0.458

High

1153912

SMAD2
Mothers against decapentaplegic homolog 2

1

0

High-throughput

0.458

High

1161669

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

1289628

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1292620

GPBP1
Vasculin

1

0

High-throughput

0.458

High

1311857

DHX40
Probable ATP-dependent RNA helicase DHX40

1

0

High-throughput

0.458

High

1313429

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1314419

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.458

High

1361233

DNJC9
DnaJ homolog subfamily C member 9

1

0

High-throughput

0.458

High

1364255

TOPB1
DNA topoisomerase 2-binding protein 1

1

0

High-throughput

0.458

High

1364594

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1384876

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

1404759

RING2
E3 ubiquitin-protein ligase RING2

1

0

High-throughput

0.458

High

1411708

RIOK1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

1414569

DDX23
Probable ATP-dependent RNA helicase DDX23

1

0

High-throughput

0.458

High

1418580

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

0

High-throughput

0.458

High

1428620

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

1434452

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

0

Small-scale

0.458

High

1434453

ANLN
Anillin

1

0

High-throughput

0.458

High

1434456

DJC17
DnaJ homolog subfamily C member 17

1

0

High-throughput

0.458

High

1434460

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.458

High

1434461

NXF1
Nuclear RNA export factor 1

1

0

High-throughput

0.458

High

1434462

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1434464

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.458

High

1434471

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

208378

RRP8
Ribosomal RNA-processing protein 8

1

1

High-throughput

0.445

High

338961

CBX6
Chromobox protein homolog 6

1

1

High-throughput

0.445

High

428981

RLA0
Large ribosomal subunit protein uL10

1

2

High-throughput

0.445

High

841461

RBM34
RNA-binding protein 34

1

2

High-throughput

0.445

High

1037367

H11
Histone H1.1

1

1

High-throughput

0.445

High

1141939

EEA1
Early endosome antigen 1

1

1

High-throughput

0.437

High

1144877

RABE1
Rab GTPase-binding effector protein 1

1

1

High-throughput

0.437

High

1434466

HECD1
E3 ubiquitin-protein ligase HECTD1

1

1

High-throughput

0.437

High

1434469

CD11A
Cyclin-dependent kinase 11A

1

1

High-throughput

0.437

High

290730

SURF6
Surfeit locus protein 6

1

0

High-throughput

0.426

High

601856

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.426

High

1130453

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.426

High

1239939

CAVN1
Caveolae-associated protein 1

1

0

High-throughput

0.426

High

1407162

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

1

0

High-throughput

0.426

High

1434451

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.426

High

1429270

ADA19
Disintegrin and metalloproteinase domain-containing protein 19

1

1

Small-scale

0.417

High

47576

RPSA2
Small ribosomal subunit protein uS2B

1

1

High-throughput

0.407

High

649423

H1T
Histone H1t

1

1

High-throughput

0.407

High

1241041

L2GL2
LLGL scribble cell polarity complex component 2

1

1

High-throughput

0.407

High

158669

TYB4Y
Thymosin beta-4, Y-chromosomal

1

0

High-throughput

0.279

Low

169210

QCR10
Cytochrome b-c1 complex subunit 10

1

0

High-throughput

0.279

Low

488082

IFI6
Interferon alpha-inducible protein 6

1

0

High-throughput

0.279

Low

699932

IP3KB
Inositol-trisphosphate 3-kinase B

1

0

High-throughput

0.279

Low

1016376

SERF2
Small EDRK-rich factor 2

1

0

High-throughput

0.279

Low

1023617

CYC
Cytochrome c

1

0

High-throughput

0.279

Low

1187922

KR197
Keratin-associated protein 19-7

1

0

High-throughput

0.279

Low

1196247

GAG2E
G antigen 2E

1

0

High-throughput

0.279

Low

1200227

LBH
Protein LBH

1

0

High-throughput

0.279

Low

1218123

CP141
Cilia- and flagella-associated protein 141

1

0

High-throughput

0.279

Low

1335954

ZBT44
Zinc finger and BTB domain-containing protein 44

1

0

High-throughput

0.279

Low

1360746

JPH3
Junctophilin-3

1

0

High-throughput

0.279

Low

1384724

I27L1
Interferon alpha-inducible protein 27-like protein 1

1

0

High-throughput

0.279

Low

1392172

RUSF1
RUS family member 1

1

0

High-throughput

0.279

Low

1398309

RN145
RING finger protein 145

1

0

High-throughput

0.279

Low

1429607

F107B
Protein FAM107B

1

0

High-throughput

0.279

Low

1434455

TM14B
Transmembrane protein 14B

1

0

High-throughput

0.279

Low

1434459

PEN2
Gamma-secretase subunit PEN-2

1

0

High-throughput

0.279

Low

1434465

ANR50
Ankyrin repeat domain-containing protein 50

1

0

High-throughput

0.279

Low

1434472

SPCS1
Signal peptidase complex subunit 1

1

0

High-throughput

0.279

Low

157850

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

253924

ABCC9
ATP-binding cassette sub-family C member 9

1

0

High-throughput

0.249

Low

598205

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

0

High-throughput

0.249

Low

646943

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.249

Low

839825

EPS15
Epidermal growth factor receptor substrate 15

1

0

High-throughput

0.249

Low

971078

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

1126175

GRM2
Metabotropic glutamate receptor 2

1

0

High-throughput

0.249

Low

1156419

SEPT7
Septin-7

1

0

High-throughput

0.249

Low

1255539

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1327195

FBXL6
F-box/LRR-repeat protein 6

1

0

High-throughput

0.249

Low

1434458

TBA8
Tubulin alpha-8 chain

1

0

High-throughput

0.249

Low

191799

MAGB2
Melanoma-associated antigen B2

1

0

High-throughput

0.232

Low

1064027

ECHP
Peroxisomal bifunctional enzyme

1

0

High-throughput

0.232

Low

1340201

ARK74
Aflatoxin B1 aldehyde reductase member 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025