HitPredict

Interactor 1: RBBP7 (Q60973)
Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)
Gene: RBBP7

Interactor 2: Q60I23 (Q60I23)
SRY (sex determining region Y)-box 2 (Sox2 protein) (Transcriptional factor SOX2)
Gene: Sox2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.39	0.60	0.484

Property	Details
Experiments	21532573
Identification Methods	anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 425 Mm			1 319
+	Hs
		818094 RBBP7_HUMAN (1-425): 6.93e-119: 354: 99.77		SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24
+	Mm
		1141928 RBBP4_MOUSE (1-425): 1.17e-114: 343: 89.20		Q60I23_MOUSE (1-319): 7.44e-64: 206: 100.00
+	Mm
		818712 RBBP4_MOUSE (1-425): 1.17e-114: 343: 89.20		SOX2_MOUSE (1-319): 1.13e-62: 203: 98.43
+	Hs
		817977 RBBP4_HUMAN (1-425): 1.17e-114: 343: 89.20		SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24
+	Hs
		1083355 RBBP7_HUMAN (1-425): 6.93e-119: 354: 99.77		CIC_HUMAN (10-274): 1.46e-36: 141: 24.28
+	Hs
		997865 RBBP4_HUMAN (1-425): 1.17e-114: 343: 89.20		CIC_HUMAN (10-274): 1.46e-36: 141: 24.28
+	Hs
		997832 RBBP4_HUMAN (1-425): 1.17e-114: 343: 89.20		BBX_HUMAN (31-257): 3.4e-33: 131: 20.78
+	Hs
		996629 RBBP4_HUMAN (1-425): 1.17e-114: 343: 89.20		SSRP1_HUMAN (21-210): 1.09e-30: 124: 15.71
+	Hs
		817868 WDR5_HUMAN (266-425): 5.9e-32: 125: 24.38		SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24
+	Hs
		817901 RACK1_HUMAN (213-405): 1.19e-28: 116: 20.41		SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24
+	Hs
		1074805 TAF5_HUMAN (7-255): 2.45e-36: 143: 17.32		CIC_HUMAN (10-274): 1.46e-36: 141: 24.28
+	Hs
		267755 TAF5L_HUMAN (32-291): 1.79e-41: 156: 16.48		SOX4_HUMAN (3-291): 1.94e-29: 119: 26.28
+	Hs
		903450 WDR5_HUMAN (266-425): 5.9e-32: 125: 24.38		CIC_HUMAN (10-274): 1.46e-36: 141: 24.28
+	Hs
		989530 TAF5_HUMAN (7-255): 2.45e-36: 143: 17.32		SOX4_HUMAN (3-291): 1.94e-29: 119: 26.28
+	Hs
		929620 RACK1_HUMAN (213-405): 1.19e-28: 116: 20.41		CIC_HUMAN (10-274): 1.46e-36: 141: 24.28
+	Hs
		903169 WDR5_HUMAN (266-425): 5.9e-32: 125: 24.38		SSRP1_HUMAN (21-210): 1.09e-30: 124: 15.71
+	Hs
		903155 WDR5_HUMAN (266-425): 5.9e-32: 125: 24.38		SRY_HUMAN (2-202): 2.3e-28: 110: 35.47
+	Hs
		996930 NLE1_HUMAN (299-424): 1.18e-19: 92.9: 19.05		SSRP1_HUMAN (21-210): 1.09e-30: 124: 15.71