Protein: K1C10
Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10)

Gene: K1C10, KRT10
Organism: Homo sapiens
Interactions: 165
UniProt ID: P13645

Gene Ontology (top 5):
GO:0001533 - cornified envelope
GO:0005615 - extracellular space
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

380548

K2C1
Keratin, type II cytoskeletal 1

1

20

Small-scale

0.761

High

531352

K1C17
Keratin, type I cytoskeletal 17

1

19

High-throughput

0.618

High

531361

CUL3
Cullin-3

2

20

High-throughput

0.611

High

531383

RICTR
Rapamycin-insensitive companion of mTOR

2

6

Small-scale

0.611

High

531318

VCAM1
Vascular cell adhesion protein 1

2

6

High-throughput

0.601

High

531325

AKT1
RAC-alpha serine/threonine-protein kinase

1

9

Small-scale

0.573

High

528448

CFTR
Cystic fibrosis transmembrane conductance regulator

2

20

Small-scale

0.571

High

531418

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

2

20

High-throughput

0.571

High

362765

FINC
Fibronectin

1

7

High-throughput

0.536

High

363707

ALBU
Albumin

1

8

High-throughput

0.536

High

531354

ZO1
Tight junction protein ZO-1

1

7

Small-scale

0.536

High

531359

CUL1
Cullin-1

1

20

High-throughput

0.536

High

531360

CUL2
Cullin-2

1

20

High-throughput

0.536

High

531362

CUL4A
Cullin-4A

1

20

High-throughput

0.536

High

531363

CUL4B
Cullin-4B

1

20

High-throughput

0.536

High

531366

FL2D
Pre-mRNA-splicing regulator WTAP

1

9

High-throughput

0.536

High

531369

NEDD8
NEDD8

1

8

High-throughput

0.536

High

531391

CSN6
COP9 signalosome complex subunit 6

1

13

High-throughput

0.536

High

531392

MTA70
N6-adenosine-methyltransferase catalytic subunit

1

15

High-throughput

0.536

High

531394

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

8

High-throughput

0.536

High

531399

RIN3
Ras and Rab interactor 3

1

3

High-throughput

0.536

High

531404

CSN5
COP9 signalosome complex subunit 5

1

20

High-throughput

0.536

High

531405

CUL5
Cullin-5

1

20

High-throughput

0.536

High

531411

DCNL1
DCN1-like protein 1

1

4

High-throughput

0.536

High

531427

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

15

High-throughput

0.536

High

522739

SRC
Proto-oncogene tyrosine-protein kinase Src

1

8

Small-scale

0.515

High

531322

DPP4
Dipeptidyl peptidase 4

1

3

High-throughput

0.515

High

531353

KPCZ
Protein kinase C zeta type

1

11

Small-scale

0.515

High

439774

NEP
Neprilysin

1

0

Small-scale

0.513

High

174590

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

2

High-throughput

0.501

High

368905

ESR1
Estrogen receptor

1

16

Small-scale

0.501

High

531345

SHPS1
Tyrosine-protein phosphatase non-receptor type substrate 1

1

8

Small-scale

0.501

High

531400

MIPT3
TRAF3-interacting protein 1

1

2

Small-scale

0.489

High

531349

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

11

High-throughput

0.484

High

310900

SNAPN
SNARE-associated protein Snapin

1

7

High-throughput

0.481

High

531377

GLE1
mRNA export factor GLE1

1

7

Small-scale

0.481

High

124748

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

13

Small-scale

0.479

High

129187

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

20

High-throughput

0.479

High

133864

DDX3X
ATP-dependent RNA helicase DDX3X

1

8

Small-scale

0.479

High

176370

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

1

12

High-throughput

0.479

High

531438

TRAF6
TNF receptor-associated factor 6

1

20

Small-scale

0.479

High

531439

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

14

Small-scale

0.479

High

197210

SERA
D-3-phosphoglycerate dehydrogenase

1

9

Small-scale

0.479

High

226395

PRKN
E3 ubiquitin-protein ligase parkin

1

17

High-throughput

0.479

High

260467

PITX3
Pituitary homeobox 3

1

7

Small-scale

0.479

High

277912

PIAS1
E3 SUMO-protein ligase PIAS1

1

3

High-throughput

0.479

High

282509

RNF8
E3 ubiquitin-protein ligase RNF8

1

16

High-throughput

0.479

High

298111

UFL1
E3 UFM1-protein ligase 1

1

3

High-throughput

0.479

High

301585

TRI37
E3 ubiquitin-protein ligase TRIM37

1

20

High-throughput

0.479

High

302854

HEXI1
Protein HEXIM1

1

20

High-throughput

0.479

High

312465

ARI2
E3 ubiquitin-protein ligase ARIH2

1

20

High-throughput

0.479

High

329304

AGR2
Anterior gradient protein 2 homolog

1

4

High-throughput

0.479

High

337854

EGFR
Epidermal growth factor receptor

1

12

High-throughput

0.479

High

345815

MYC
Myc proto-oncogene protein

1

15

High-throughput

0.479

High

352466

TNFA
Tumor necrosis factor

1

5

High-throughput

0.479

High

353375

PIGR
Polymeric immunoglobulin receptor

1

1

Small-scale

0.479

High

378969

MYCN
N-myc proto-oncogene protein

1

15

High-throughput

0.479

High

386009

P53
Cellular tumor antigen p53

1

9

Small-scale

0.479

High

414554

PTMA
Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha-1]

1

5

Small-scale

0.479

High

428901

ADRB2
Beta-2 adrenergic receptor

1

2

High-throughput

0.479

High

450697

F16P1
Fructose-1,6-bisphosphatase 1

1

7

High-throughput

0.479

High

453116

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

14

High-throughput

0.479

High

488552

ARAF
Serine/threonine-protein kinase A-Raf

1

7

High-throughput

0.479

High

530394

ITA4
Integrin alpha-4

1

5

High-throughput

0.479

High

531319

BTF3
Transcription factor BTF3

1

4

High-throughput

0.479

High

531321

CBL
E3 ubiquitin-protein ligase CBL

1

12

High-throughput

0.479

High

531323

SHC1
SHC-transforming protein 1

1

20

High-throughput

0.479

High

531324

EF1D
Elongation factor 1-delta

1

3

Small-scale

0.479

High

531326

1433S
14-3-3 protein sigma

1

16

Small-scale

0.479

High

531327

PHB1
Prohibitin 1

1

1

High-throughput

0.479

High

531328

ARL3
ADP-ribosylation factor-like protein 3

1

12

High-throughput

0.479

High

531329

IF4A3
Eukaryotic initiation factor 4A-III

1

17

High-throughput

0.479

High

531330

EPS15
Epidermal growth factor receptor substrate 15

1

18

High-throughput

0.479

High

531331

CRK
Adapter molecule crk

1

20

High-throughput

0.479

High

531334

ARL4D
ADP-ribosylation factor-like protein 4D

1

13

High-throughput

0.479

High

531335

CDK9
Cyclin-dependent kinase 9

1

6

High-throughput

0.479

High

531339

TERA
Transitional endoplasmic reticulum ATPase

1

7

High-throughput

0.479

High

531341

MGN
Protein mago nashi homolog

1

5

High-throughput

0.479

High

531342

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

14

High-throughput

0.479

High

531343

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.479

High

531344

H31
Histone H3.1

1

1

High-throughput

0.479

High

531347

ARF1
ADP-ribosylation factor 1

1

8

High-throughput

0.479

High

531348

ARF5
ADP-ribosylation factor 5

1

8

High-throughput

0.479

High

531350

NFKB2
Nuclear factor NF-kappa-B p100 subunit

1

3

High-throughput

0.479

High

531351

MDM2
E3 ubiquitin-protein ligase Mdm2

1

1

Small-scale

0.479

High

531355

ARL16
ADP-ribosylation factor-like protein 16

1

15

High-throughput

0.479

High

531357

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

20

High-throughput

0.479

High

531364

DX39B
Spliceosome RNA helicase DDX39B

1

20

Small-scale

0.479

High

531365

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

20

High-throughput

0.479

High

531367

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

10

High-throughput

0.479

High

531368

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

20

High-throughput

0.479

High

531370

EZH2
Histone-lysine N-methyltransferase EZH2

1

16

High-throughput

0.479

High

531372

MK06
Mitogen-activated protein kinase 6

1

3

High-throughput

0.479

High

531374

LARP7
La-related protein 7

1

17

High-throughput

0.479

High

531375

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

11

High-throughput

0.479

High

531376

MIDN
Midnolin

1

3

High-throughput

0.479

High

531378

EMC4
ER membrane protein complex subunit 4

1

5

High-throughput

0.479

High

531381

VIR
Protein virilizer homolog

1

6

High-throughput

0.479

High

531382

PRP8
Pre-mRNA-processing-splicing factor 8

1

11

High-throughput

0.479

High

531385

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

8

High-throughput

0.479

High

531386

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

531390

MEPCE
7SK snRNA methylphosphate capping enzyme

1

16

High-throughput

0.479

High

531395

RHG24
Rho GTPase-activating protein 24

1

7

High-throughput

0.479

High

531398

TNIP2
TNFAIP3-interacting protein 2

1

8

High-throughput

0.479

High

531401

UBS3B
Ubiquitin-associated and SH3 domain-containing protein B

1

20

High-throughput

0.479

High

531402

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

14

High-throughput

0.479

High

531403

HDAC2
Histone deacetylase 2

1

16

High-throughput

0.479

High

531406

LRC59
Leucine-rich repeat-containing protein 59

1

1

High-throughput

0.479

High

531407

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

9

Small-scale

0.479

High

531408

DCPS
m7GpppX diphosphatase

1

3

High-throughput

0.479

High

531409

AP2M1
AP-2 complex subunit mu

1

9

High-throughput

0.479

High

531410

RNF31
E3 ubiquitin-protein ligase RNF31

1

20

High-throughput

0.479

High

531413

DDRGK
DDRGK domain-containing protein 1

1

3

High-throughput

0.479

High

531414

NECD
Necdin

1

7

High-throughput

0.479

High

531415

ACE2
Angiotensin-converting enzyme 2

1

9

High-throughput

0.479

High

531416

TRI31
E3 ubiquitin-protein ligase TRIM31

1

14

High-throughput

0.479

High

531419

DDX24
ATP-dependent RNA helicase DDX24

1

20

High-throughput

0.479

High

531421

RN208
RING finger protein 208

1

20

Small-scale

0.479

High

531422

GAN
Gigaxonin

1

12

High-throughput

0.479

High

531423

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

5

Small-scale

0.479

High

531425

RC3H2
Roquin-2

1

20

High-throughput

0.479

High

531426

NMRL1
NmrA-like family domain-containing protein 1

1

3

High-throughput

0.479

High

531428

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

15

High-throughput

0.479

High

531429

ANLN
Anillin

1

13

High-throughput

0.479

High

531431

PIHD1
PIH1 domain-containing protein 1

1

3

High-throughput

0.479

High

531432

HDAC6
Histone deacetylase 6

1

20

High-throughput

0.479

High

531433

KS6B2
Ribosomal protein S6 kinase beta-2

1

9

High-throughput

0.479

High

531434

ZRAN1
Ubiquitin thioesterase ZRANB1

1

16

High-throughput

0.479

High

531435

FBXL4
F-box/LRR-repeat protein 4

1

2

Small-scale

0.479

High

531436

FAF1
FAS-associated factor 1

1

3

High-throughput

0.479

High

351919

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.458

High

531336

HDGF
Hepatoma-derived growth factor

1

0

High-throughput

0.458

High

531356

MN1
Transcriptional activator MN1

1

0

Small-scale

0.458

High

531371

CRY1
Cryptochrome-1

1

0

High-throughput

0.458

High

275373

PR15A
Protein phosphatase 1 regulatory subunit 15A

1

1

High-throughput

0.445

High

305937

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

20

High-throughput

0.445

High

353628

IGHG1
Immunoglobulin heavy constant gamma 1

1

12

High-throughput

0.445

High

354033

IGHA1
Immunoglobulin heavy constant alpha 1

1

12

High-throughput

0.445

High

496198

TAU
Microtubule-associated protein tau

1

6

High-throughput

0.445

High

531340

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

20

High-throughput

0.445

High

531358

CTBP1
C-terminal-binding protein 1

1

9

High-throughput

0.445

High

531379

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

9

High-throughput

0.445

High

531393

TLK2
Serine/threonine-protein kinase tousled-like 2

1

12

High-throughput

0.445

High

531420

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

20

High-throughput

0.445

High

531424

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

20

High-throughput

0.445

High

531320

EFNA1
Ephrin-A1

1

20

High-throughput

0.437

High

531333

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

3

High-throughput

0.437

High

531337

EFNA3
Ephrin-A3

1

20

High-throughput

0.437

High

531338

EFNA4
Ephrin-A4

1

20

High-throughput

0.437

High

531373

MINY4
Probable ubiquitin carboxyl-terminal hydrolase MINDY-4

1

4

Small-scale

0.437

High

531380

RC3H1
Roquin-1

1

14

High-throughput

0.437

High

531384

LRC31
Leucine-rich repeat-containing protein 31

1

12

High-throughput

0.437

High

531388

ASXL2
Putative Polycomb group protein ASXL2

1

6

High-throughput

0.437

High

531389

KCTD9
BTB/POZ domain-containing protein KCTD9

1

5

High-throughput

0.437

High

531396

ARL10
ADP-ribosylation factor-like protein 10

1

15

High-throughput

0.437

High

531412

DIRA2
GTP-binding protein Di-Ras2

1

3

Small-scale

0.437

High

531417

ASXL3
Putative Polycomb group protein ASXL3

1

3

High-throughput

0.437

High

531430

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

5

High-throughput

0.437

High

531437

AAR2
Protein AAR2 homolog

1

7

High-throughput

0.437

High

531440

INSI2
Insulin-induced gene 2 protein

1

3

High-throughput

0.437

High

531332

RS9
Small ribosomal subunit protein uS4

1

0

Small-scale

0.426

High

531346

SMAD3
Mothers against decapentaplegic homolog 3

1

0

Small-scale

0.426

High

913

SIM26
Small integral membrane protein 26

1

6

High-throughput

0.407

High

531387

NEK10
Serine/threonine-protein kinase Nek10

1

6

High-throughput

0.407

High

531397

MOT11
Monocarboxylate transporter 11

1

5

High-throughput

0.407

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024