HitPredict

Interactor 1: FZD7 (Q61090)
Frizzled-7 (Fz-7) (mFz7)
Gene: FZD7

Interactor 2: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.42	0.60	0.506

Property	Details
Experiments	12067714
Identification Methods	two hybrid array, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005109 - frizzled binding GO:0005886 - plasma membrane GO:0030165 - PDZ domain binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 572 Mm			1 724
+	Hs
		254162 FZD7_HUMAN (1-572): 0: 793: 96.34		DLG4_HUMAN (1-724): 0: 671: 99.59
+	Hs
		942398 FZD1_HUMAN (35-572): 0: 755: 79.30		DLG4_HUMAN (1-724): 0: 671: 99.59
+	Mm
		250809 FZD1_MOUSE (35-572): 0: 752: 78.94		DLG4_MOUSE (1-724): 0: 671: 100.00
+	Mm
		1143526 FZD2_MOUSE (34-572): 0: 750: 79.15		DLG4_MOUSE (1-724): 0: 671: 100.00
+	Hs
		942341 FZD2_HUMAN (34-572): 0: 748: 79.15		DLG4_HUMAN (1-724): 0: 671: 99.59
+	Mm
		1142152 FZD7_MOUSE (1-572): 0: 804: 100.00		DLG1_MOUSE (8-724): 0: 577: 68.93
+	Mm
		250810 FZD1_MOUSE (35-572): 0: 752: 78.94		DLG1_MOUSE (8-724): 0: 577: 68.93
+	Hs
		942397 FZD4_HUMAN (37-567): 0: 614: 42.86		DLG4_HUMAN (1-724): 0: 671: 99.59
+	Mm
		1142145 FZD4_MOUSE (36-567): 0: 610: 42.59		DLG4_MOUSE (1-724): 0: 671: 100.00
+	Mm
		1142147 FZD4_MOUSE (36-567): 0: 610: 42.59		DLG1_MOUSE (8-724): 0: 577: 68.93
+	Mm
		1142153 FZD7_MOUSE (1-572): 0: 804: 100.00		DLG2_MOUSE (234-473): 4.91e-17: 87.8: 21.95
+	Mm
		250811 FZD1_MOUSE (35-572): 0: 752: 78.94		DLG2_MOUSE (234-473): 4.91e-17: 87.8: 21.95
+	Mm
		1142148 FZD4_MOUSE (36-567): 0: 610: 42.59		DLG2_MOUSE (234-473): 4.91e-17: 87.8: 21.95