HitPredict

Interactor 1: EZH2 (Q61188)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2)
Gene: EZH2

Interactor 2: AEBP2 (Q9Z248)
Zinc finger protein AEBP2 (Adipocyte enhancer-binding protein 2) (AE-binding protein 2)
Gene: AEBP2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.656

The method score is based on:

Property Details
Experiments 25680957, 20123894, 20064376
Identification Methods proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0035098 - ESC/E(Z) complex
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 746
Mm

1 504
+ Hs
+ Mm
+ Mm
+ Hs
+ Dm
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
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+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024