HitPredict

Interactor 1: ERR2 (Q61539)
Steroid hormone receptor ERR2 (Estrogen receptor-like 2) (Estrogen-related receptor beta) (ERR-beta) (Nuclear receptor subfamily 3 group B member 2)
Gene: Esrrb

Interactor 2: SMRC2 (Q6PDG5)
SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)
Gene: Smarcc2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26206133
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006357 - regulation of transcription by RNA polymerase II GO:0045892 - negative regulation of DNA-templated transcription GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 433 Mm			1 1213
+	Mm
		956817 ERR2_MOUSE (1-433): 3.74e-165: 473: 100.00		SMRC1_MOUSE (4-1108): 0: 963: 60.94
+	Mm
		521438 NR4A1_MOUSE (34-429): 4.76e-108: 333: 30.37		SMRC1_MOUSE (4-1108): 0: 963: 60.94
+	Hs
		587211 RXRA_HUMAN (8-431): 1.52e-128: 381: 28.44		NCOR2_HUMAN (545-1199): 2.9e-37: 155: 11.34
+	Hs
		818890 RXRG_HUMAN (11-431): 3.15e-128: 380: 29.89		NCOR2_HUMAN (545-1199): 2.9e-37: 155: 11.34
+	Hs
		261399 RXRA_HUMAN (8-431): 1.52e-128: 381: 28.44		NCOR1_HUMAN (545-1142): 9.92e-29: 127: 10.61
+	Hs
		1069095 Q15156_HUMAN (101-430): 1.09e-111: 348: 30.51		NCOR2_HUMAN (545-1199): 2.9e-37: 155: 11.34
+	Hs
		500380 RARB_HUMAN (41-430): 2.54e-115: 347: 28.32		NCOR2_HUMAN (545-1199): 2.9e-37: 155: 11.34
+	Hs
		370824 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		NCOR2_HUMAN (545-1199): 2.9e-37: 155: 11.34
+	Hs
		795610 NR4A2_HUMAN (32-429): 3.36e-110: 338: 27.38		NCOR2_HUMAN (545-1199): 2.9e-37: 155: 11.34
+	Hs
		488042 RARA_HUMAN (38-430): 2.72e-111: 336: 27.64		NCOR2_HUMAN (545-1199): 2.9e-37: 155: 11.34
+	Hs
		261369 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		NCOR1_HUMAN (545-1142): 9.92e-29: 127: 10.61
+	Hs
		261381 RARA_HUMAN (38-430): 2.72e-111: 336: 27.64		NCOR1_HUMAN (545-1142): 9.92e-29: 127: 10.61
+	Hs
		261429 HNF4A_HUMAN (78-429): 2.37e-109: 332: 28.61		NCOR1_HUMAN (545-1142): 9.92e-29: 127: 10.61
+	Hs
		587190 RXRA_HUMAN (8-431): 1.52e-128: 381: 28.44		CBP_HUMAN (725-1209): 1.33e-09: 65: 11.94
+	Hs
		370607 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		CHD7_HUMAN (843-1213): 3.97e-11: 70.1: 11.54
+	Hs
		370040 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		KMT2C_HUMAN (656-1210): 1.3e-09: 65: 11.00
+	Hs
		370136 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		CBP_HUMAN (725-1209): 1.33e-09: 65: 11.94
+	Hs
		795602 NR4A2_HUMAN (32-429): 3.36e-110: 338: 27.38		CBP_HUMAN (725-1209): 1.33e-09: 65: 11.94
+	Hs
		488001 RARA_HUMAN (38-430): 2.72e-111: 336: 27.64		CBP_HUMAN (725-1209): 1.33e-09: 65: 11.94
+	Hs
		782595 HNF4A_HUMAN (78-429): 2.37e-109: 332: 28.61		KMT2C_HUMAN (656-1210): 1.3e-09: 65: 11.00