HitPredict

Interactor 1: ERR2 (Q61539)
Steroid hormone receptor ERR2 (Estrogen receptor-like 2) (Estrogen-related receptor beta) (ERR-beta) (Nuclear receptor subfamily 3 group B member 2)
Gene: Esrrb

Interactor 2: EP400 (Q8CHI8)
E1A-binding protein p400 (EC 3.6.4.-) (Domino homolog) (mDomino) (p400 kDa SWI2/SNF2-related protein)
Gene: EP400

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	26206133, 20362541
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 433 Mm			1 3072
+	Mm
		1142705 ERR2_MOUSE (1-433): 3.74e-165: 473: 100.00		SMCA5_MOUSE (1586-2266): 1.19e-107: 374: 16.25
+	Mm
		1142661 ERR2_MOUSE (1-433): 3.74e-165: 473: 100.00		CHD4_MOUSE (1525-2397): 9.85e-93: 339: 13.70
+	Hs
		229273 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		SMCA5_HUMAN (1586-2266): 1.1e-107: 374: 16.40
+	Hs
		369621 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		CHD4_HUMAN (1525-2404): 5.1e-94: 343: 14.05
+	Hs
		587181 RXRA_HUMAN (8-431): 1.52e-128: 381: 28.44		CHD9_HUMAN (1613-2114): 1.33e-81: 304: 17.81
+	Hs
		151369 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		CHD1_HUMAN (1442-2414): 5.37e-93: 339: 12.62
+	Hs
		151470 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		CHD2_HUMAN (1559-2461): 5.23e-89: 326: 13.39
+	Hs
		587141 RXRA_HUMAN (8-431): 1.52e-128: 381: 28.44		SMCA4_HUMAN (1597-2187): 3.54e-75: 281: 14.43
+	Hs
		369729 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		CHD9_HUMAN (1613-2114): 1.33e-81: 304: 17.81
+	Hs
		370065 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		CHD6_HUMAN (1765-2137): 3.11e-81: 302: 24.68
+	Hs
		370686 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		INO80_HUMAN (1667-2066): 2.55e-80: 297: 26.16
+	Hs
		622838 COT2_HUMAN (27-429): 2.01e-117: 351: 29.14		SMRCD_HUMAN (1341-1984): 1.46e-78: 286: 15.76
+	Hs
		369213 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		SMCA2_HUMAN (1598-2260): 4.27e-76: 284: 15.02
+	Hs
		369214 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		SMCA4_HUMAN (1597-2187): 3.54e-75: 281: 14.43
+	Hs
		795589 NR4A2_HUMAN (32-429): 3.36e-110: 338: 27.38		SMCA2_HUMAN (1598-2260): 4.27e-76: 284: 15.02
+	Hs
		795590 NR4A2_HUMAN (32-429): 3.36e-110: 338: 27.38		SMCA4_HUMAN (1597-2187): 3.54e-75: 281: 14.43
+	Mm
		1111929 ERR2_MOUSE (1-433): 3.74e-165: 473: 100.00		SMCA4_MOUSE (2483-2855): 7.18e-09: 64.1: 13.90
+	Hs
		370225 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		EP400_HUMAN (1380-1693): 5.2e-13: 78.1: 8.15
+	Hs
		370482 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		CHD8_HUMAN (2475-3056): 4.33e-12: 74.7: 13.57
+	Hs
		370607 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		CHD7_HUMAN (6-460): 2.38e-09: 65.7: 13.83