HitPredict

Interactor 1: GRID2 (Q61625)
Glutamate receptor ionotropic, delta-2 (GluD2) (GluR delta-2 subunit)
Gene: GRID2

Interactor 2: GOPC (Q8BH60)
Golgi-associated PDZ and coiled-coil motif-containing protein (CFTR-associated ligand) (PDZ protein interacting specifically with TC10) (PIST)
Gene: GOPC

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.529

Property	Details
Experiments	12372286
Identification Methods	two hybrid, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0045202 - synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1007 Mm			1 463
+	Hs
		203185 GRID2_HUMAN (1-1007): 0: 903: 97.62		GOPC_HUMAN (25-463): 4.16e-109: 332: 92.03
+	Mm
		1142984 GRID1_MOUSE (1-1007): 0: 785: 55.61		GOPC_MOUSE (11-463): 3.69e-109: 332: 100.00
+	Rn
		1144131 GRID2_RAT (1-1007): 0: 911: 99.50		DLG2_RAT (8-454): 9.03e-34: 137: 16.38
+	Mm
		1142961 GRID2_MOUSE (1-1007): 0: 912: 100.00		DLG4_MOUSE (8-311): 6.48e-17: 85.5: 9.68
+	Rn
		677792 GRID2_RAT (1-1007): 0: 911: 99.50		DLG4_RAT (8-311): 6.37e-17: 85.5: 9.68
+	Rn
		1143996 GRID1_RAT (1-1007): 0: 784: 55.71		DLG2_RAT (8-454): 9.03e-34: 137: 16.38
+	Mm
		1142983 GRID1_MOUSE (1-1007): 0: 785: 55.61		DLG4_MOUSE (8-311): 6.48e-17: 85.5: 9.68
+	Rn
		291503 GRID1_RAT (1-1007): 0: 784: 55.71		MAGI2_RAT (294-462): 4.81e-17: 86.3: 15.79
+	Mm
		620904 GRIA1_MOUSE (6-889): 0: 719: 24.53		DLG2_MOUSE (8-454): 4.45e-34: 137: 15.07
+	Hs
		1022366 GRIK2_HUMAN (8-924): 0: 736: 26.72		DLG3_HUMAN (8-258): 3.29e-19: 92.8: 10.20
+	Rn
		677766 GRIK2_RAT (8-924): 0: 736: 26.61		DLG4_RAT (8-311): 6.37e-17: 85.5: 9.68
+	Hs
		942335 GRIK2_HUMAN (8-924): 0: 736: 26.72		DLG4_HUMAN (8-311): 7.15e-17: 85.5: 9.68
+	Hs
		761199 GRIK1_HUMAN (4-860): 0: 735: 27.75		DLG4_HUMAN (8-311): 7.15e-17: 85.5: 9.68
+	Mm
		761217 GRIK2_MOUSE (8-924): 0: 735: 26.61		DLG4_MOUSE (8-311): 6.48e-17: 85.5: 9.68
+	Mm
		620881 GRIA1_MOUSE (6-889): 0: 719: 24.53		DLG3_MOUSE (8-258): 1.37e-18: 90.9: 11.33
+	Rn
		585138 GRIA1_RAT (6-889): 0: 722: 24.64		DLG4_RAT (8-311): 6.37e-17: 85.5: 9.68
+	Mm
		620892 GRIA1_MOUSE (6-889): 0: 719: 24.53		DLG4_MOUSE (8-311): 6.48e-17: 85.5: 9.68
+	Hs
		786757 GRIA3_HUMAN (6-871): 0: 703: 25.31		DLG4_HUMAN (8-311): 7.15e-17: 85.5: 9.68
+	Mm
		1143566 GRIA3_MOUSE (6-871): 0: 702: 25.20		DLG4_MOUSE (8-311): 6.48e-17: 85.5: 9.68
+	Mm
		1143565 GRIA4_MOUSE (10-865): 0: 699: 25.57		DLG4_MOUSE (8-311): 6.48e-17: 85.5: 9.68