Interactor 1: M3K7 (Q62073)
Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)
Gene: Map3k7

Interactor 2: HIPK2 (Q9QZR5)
Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (Nuclear body-associated kinase 1) (Sialophorin tail-associated nuclear serine/threonine-protein kinase)
Gene: HIPK2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.646

The method score is based on:

Property Details
Experiments 23565059
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0006468 - protein phosphorylation
GO:0007179 - transforming growth factor beta receptor signaling pathway
GO:0046330 - positive regulation of JNK cascade
and 1 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 579
Mm

1 1196
+ Hs
+ Hs
+ Hs
+ Hs
+ Zm
+ At
+ At
+ At
+ At
+ At
+ At
+ Hs
+ Hs

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Last updated: 15 Jul 2024