HitPredict

Interactor 1: SRSF2 (Q62093)
Serine/arginine-rich splicing factor 2 (Protein PR264) (Putative myelin regulatory factor 1) (MRF-1) (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2)
Gene: SRSF2

Interactor 2: HTSF1 (Q8BGC0)
17S U2 SnRNP complex component HTATSF1 (HIV Tat-specific factor 1 homolog)
Gene: Htatsf1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.646

Property	Details
Experiments	18641664
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 221 Mm			1 757
+	Hs
		641795 SF3B4_HUMAN (4-205): 1.41e-52: 176: 17.24		U2AF2_HUMAN (74-357): 1.76e-52: 191: 19.26
+	Hs
		516364 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		U2AF2_HUMAN (74-357): 1.76e-52: 191: 19.26
+	Hs
		641724 SRSF2_HUMAN (1-221): 1.22e-43: 147: 100.00		U2AF2_HUMAN (74-357): 1.76e-52: 191: 19.26
+	Hs
		967197 SF3B4_HUMAN (4-205): 1.41e-52: 176: 17.24		EWS_HUMAN (34-220): 6.51e-34: 140: 15.96
+	Hs
		726840 SF3B4_HUMAN (4-205): 1.41e-52: 176: 17.24		FUS_HUMAN (110-217): 7.14e-25: 111: 22.94
+	Hs
		963966 SRSF2_HUMAN (1-221): 1.22e-43: 147: 100.00		EWS_HUMAN (34-220): 6.51e-34: 140: 15.96
+	Hs
		516339 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		PABP1_HUMAN (70-233): 6.45e-32: 134: 14.97
+	Hs
		516689 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		PABP3_HUMAN (1-262): 7.89e-32: 133: 13.16
+	Hs
		1054336 SF3B4_HUMAN (4-205): 1.41e-52: 176: 17.24		RBM39_HUMAN (135-347): 5.86e-23: 105: 19.32
+	Hs
		516495 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		PABP4_HUMAN (63-233): 7.58e-31: 131: 17.98
+	Dm
		1370593 Q9W424_DROME (4-205): 1.68e-50: 168: 17.24		Q9VM49_DROME (113-347): 3.75e-25: 112: 21.07
+	Hs
		516484 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		ELAV2_HUMAN (117-403): 5.06e-31: 127: 14.82
+	Mm
		665745 PABP1_MOUSE (6-202): 2.07e-41: 150: 18.27		TIA1_MOUSE (1-244): 3.91e-26: 113: 14.67
+	Hs
		516383 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		FUS_HUMAN (110-217): 7.14e-25: 111: 22.94
+	Mm
		857332 SRSF2_MOUSE (1-221): 1.22e-43: 147: 100.00		TIA1_MOUSE (1-244): 3.91e-26: 113: 14.67
+	Mm
		882688 SRSF2_MOUSE (1-221): 1.22e-43: 147: 100.00		FUS_MOUSE (110-217): 1.65e-25: 113: 22.94
+	Hs
		516518 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		RBM39_HUMAN (135-347): 5.86e-23: 105: 19.32
+	Hs
		963985 SRSF2_HUMAN (1-221): 1.22e-43: 147: 100.00		RBM39_HUMAN (135-347): 5.86e-23: 105: 19.32
+	Hs
		474019 ELAV2_HUMAN (1-195): 6.01e-38: 136: 15.79		PAB4L_HUMAN (74-220): 5.03e-19: 91.6: 19.48