Protein: ITB5
Integrin beta-5

Gene: ITB5, ITGB5
Organism: Homo sapiens
Interactions: 129
UniProt ID: P18084

Gene Ontology (top 5):
GO:0001618 - virus receptor activity
GO:0005178 - integrin binding
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
GO:0007160 - cell-matrix adhesion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

419152

ITAV
Integrin alpha-V

2

20

Small-scale

0.789

High

574558

TITIN
Titin

1

9

High-throughput

0.698

High

574503

CEAM8
Carcinoembryonic antigen-related cell adhesion molecule 8

1

6

High-throughput

0.691

High

574507

I12R1
Interleukin-12 receptor subunit beta-1

1

8

High-throughput

0.691

High

574582

BTNL2
Butyrophilin-like protein 2

1

6

High-throughput

0.691

High

216377

EDIL3
EGF-like repeat and discoidin I-like domain-containing protein 3

3

11

High-throughput

0.667

High

372992

VTNC
Vitronectin

3

4

Small-scale

0.667

High

574530

MFGM
Lactadherin

3

7

High-throughput

0.667

High

574585

ADA21
Disintegrin and metalloproteinase domain-containing protein 21

2

12

High-throughput

0.628

High

574539

MYPC2
Myosin-binding protein C, fast-type

1

6

High-throughput

0.625

High

574526

FAK1
Focal adhesion kinase 1

2

19

Small-scale

0.624

High

362793

FINC
Fibronectin

1

14

Small-scale

0.618

High

443034

ITA5
Integrin alpha-5

1

20

Small-scale

0.618

High

574498

ITA3
Integrin alpha-3

1

20

Small-scale

0.618

High

574501

EPHA2
Ephrin type-A receptor 2

1

11

Small-scale

0.618

High

574508

MUC18
Cell surface glycoprotein MUC18

1

6

High-throughput

0.618

High

574509

DCC
Netrin receptor DCC

1

6

Small-scale

0.618

High

574587

KLK5
Kallikrein-5

3

4

High-throughput

0.609

High

66978

CRTP1
Cysteine-rich tail protein 1

2

2

High-throughput

0.606

High

327951

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

2

8

High-throughput

0.606

High

574538

FHL3
Four and a half LIM domains protein 3

2

9

High-throughput

0.606

High

574540

K1H1
Keratin, type I cuticular Ha1

2

6

High-throughput

0.606

High

574515

KR108
Keratin-associated protein 10-8

3

20

High-throughput

0.597

High

574516

KR109
Keratin-associated protein 10-9

3

20

High-throughput

0.597

High

574543

MTUS2
Microtubule-associated tumor suppressor candidate 2

3

8

High-throughput

0.597

High

574566

TIMD4
T-cell immunoglobulin and mucin domain-containing protein 4

1

0

Small-scale

0.586

High

574510

AT1B3
Sodium/potassium-transporting ATPase subunit beta-3

2

0

High-throughput

0.585

High

574519

RB11A
Ras-related protein Rab-11A

2

3

High-throughput

0.584

High

574555

ZN655
Zinc finger protein 655

2

0

High-throughput

0.580

High

574559

SIA8D
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

2

2

High-throughput

0.574

High

574574

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

2

12

High-throughput

0.574

High

330845

PAK4
Serine/threonine-protein kinase PAK 4

1

4

Small-scale

0.573

High

444829

ANXA5
Annexin A5

1

1

Small-scale

0.561

High

574502

PDIA3
Protein disulfide-isomerase A3

1

5

Small-scale

0.561

High

574551

FRMD5
FERM domain-containing protein 5

1

6

Small-scale

0.561

High

574556

STAB2
Stabilin-2

1

12

Small-scale

0.561

High

574579

MYO10
Unconventional myosin-X

1

5

Small-scale

0.561

High

280523

KRT34
Keratin, type I cuticular Ha4

2

6

High-throughput

0.553

High

574514

KR107
Keratin-associated protein 10-7

2

20

High-throughput

0.553

High

574528

KRA11
Keratin-associated protein 1-1

2

20

High-throughput

0.553

High

574529

GOGA2
Golgin subfamily A member 2

2

6

High-throughput

0.553

High

574547

KRA57
Keratin-associated protein 5-7

2

20

High-throughput

0.553

High

574552

KRA13
Keratin-associated protein 1-3

2

19

High-throughput

0.553

High

574561

APBP2
Amyloid protein-binding protein 2

2

4

High-throughput

0.553

High

574572

KRA32
Keratin-associated protein 3-2

2

1

High-throughput

0.553

High

574549

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.553

High

372885

TRGV3
T cell receptor gamma variable 3

1

0

High-throughput

0.546

High

381789

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

1

High-throughput

0.541

High

318350

ECEL1
Endothelin-converting enzyme-like 1

1

3

High-throughput

0.536

High

449183

LEG1
Galectin-1

1

10

High-throughput

0.536

High

574497

PRTN3
Myeloblastin

1

7

High-throughput

0.536

High

574499

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

10

High-throughput

0.536

High

574500

CALX
Calnexin

1

3

High-throughput

0.536

High

574527

NKG2E
NKG2-E type II integral membrane protein

1

10

High-throughput

0.536

High

574560

CLC2B
C-type lectin domain family 2 member B

1

10

High-throughput

0.536

High

574563

T106A
Transmembrane protein 106A

1

1

High-throughput

0.536

High

574575

CNTP3
Contactin-associated protein-like 3

1

16

High-throughput

0.536

High

574584

ADA30
Disintegrin and metalloproteinase domain-containing protein 30

1

12

High-throughput

0.536

High

574550

NT2NA
Notch homolog 2 N-terminal-like protein A

2

15

High-throughput

0.533

High

574505

FDFT
Squalene synthase

1

0

High-throughput

0.518

High

363715

ALBU
Albumin

1

0

High-throughput

0.513

High

410545

CD1A
T-cell surface glycoprotein CD1a

1

0

High-throughput

0.513

High

574554

LYPD1
Ly6/PLAUR domain-containing protein 1

1

0

High-throughput

0.513

High

574565

ASIC4
Acid-sensing ion channel 4

1

0

High-throughput

0.513

High

574578

LRRC4
Leucine-rich repeat-containing protein 4

1

0

High-throughput

0.513

High

574562

TRI63
E3 ubiquitin-protein ligase TRIM63

1

8

High-throughput

0.504

High

489562

OSTP
Osteopontin

1

1

Small-scale

0.501

High

574531

EPS8
Epidermal growth factor receptor kinase substrate 8

1

7

Small-scale

0.501

High

574544

TENS2
Tensin-2

1

6

Small-scale

0.501

High

574496

TAF1
Transcription initiation factor TFIID subunit 1

1

2

High-throughput

0.494

High

574541

GON4L
GON-4-like protein

1

1

High-throughput

0.494

High

574573

TRI55
Tripartite motif-containing protein 55

1

8

High-throughput

0.494

High

180116

SIA8E
Alpha-2,8-sialyltransferase 8E

1

2

High-throughput

0.489

High

197123

SIA8C
Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase ST8SIA3

1

2

High-throughput

0.489

High

574542

GXLT1
Glucoside xylosyltransferase 1

1

1

High-throughput

0.489

High

574548

BRID5
BRICHOS domain-containing protein 5

1

1

High-throughput

0.489

High

574576

KLK15
Kallikrein-15

1

7

High-throughput

0.489

High

574583

FBX2
F-box only protein 2

1

7

High-throughput

0.489

High

574586

PRG3
Proteoglycan 3

1

5

High-throughput

0.489

High

574535

SNTA1
Alpha-1-syntrophin

1

3

Small-scale

0.481

High

2089

TVA20
T cell receptor alpha variable 20

1

0

High-throughput

0.481

High

574524

EWS
RNA-binding protein EWS

1

4

High-throughput

0.481

High

134575

CCN1
CCN family member 1

1

0

Small-scale

0.480

High

146014

CLD4
Claudin-4

1

1

Small-scale

0.479

High

178390

STX7
Syntaxin-7

1

2

High-throughput

0.479

High

205020

TGON2
Trans-Golgi network integral membrane protein 2

1

11

High-throughput

0.479

High

349863

RASK
GTPase KRas

1

15

High-throughput

0.479

High

436152

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

499517

CH60
60 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.479

High

521663

ACE
Angiotensin-converting enzyme

1

3

Small-scale

0.479

High

528505

CFTR
Cystic fibrosis transmembrane conductance regulator

1

5

High-throughput

0.479

High

545199

RAC2
Ras-related C3 botulinum toxin substrate 2

1

18

High-throughput

0.479

High

574495

RAB4A
Ras-related protein Rab-4A

1

6

High-throughput

0.479

High

574504

TSP4
Thrombospondin-4

1

10

Small-scale

0.479

High

574506

BCL6
B-cell lymphoma 6 protein

1

1

High-throughput

0.479

High

574511

RAB25
Ras-related protein Rab-25

1

3

High-throughput

0.479

High

574517

RAB2A
Ras-related protein Rab-2A

1

6

High-throughput

0.479

High

574518

ARF6
ADP-ribosylation factor 6

1

1

High-throughput

0.479

High

574520

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

574521

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

574536

ADAM9
Disintegrin and metalloproteinase domain-containing protein 9

1

11

Small-scale

0.479

High

574537

CUL3
Cullin-3

1

3

High-throughput

0.479

High

574564

FERM2
Fermitin family homolog 2

1

17

Small-scale

0.479

High

574571

ACE2
Angiotensin-converting enzyme 2

1

3

Small-scale

0.479

High

574577

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

574581

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

574588

TLN2
Talin-2

1

15

Small-scale

0.479

High

484564

NT2NC
Notch homolog 2 N-terminal-like protein C

1

15

High-throughput

0.470

High

574532

ZBT17
Zinc finger and BTB domain-containing protein 17

1

0

Small-scale

0.460

High

117347

BACH
Cytosolic acyl coenzyme A thioester hydrolase

1

0

High-throughput

0.458

High

574513

MYPR
Myelin proteolipid protein

1

0

Small-scale

0.458

High

574570

ANGL4
Angiopoietin-related protein 4

1

4

Small-scale

0.457

High

574522

RACK1
Small ribosomal subunit protein RACK1

1

5

Small-scale

0.457

High

574512

CD81
CD81 antigen

1

19

High-throughput

0.445

High

476

NBPFJ
Neuroblastoma breakpoint family member 19

1

6

High-throughput

0.439

High

574525

PPARD
Peroxisome proliferator-activated receptor delta

1

1

High-throughput

0.439

High

574533

SRSF9
Serine/arginine-rich splicing factor 9

1

1

High-throughput

0.439

High

574546

K1C40
Keratin, type I cytoskeletal 40

1

6

High-throughput

0.439

High

574567

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

2

High-throughput

0.439

High

344934

CYTN
Cystatin-SN

1

3

Small-scale

0.437

High

574523

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

574534

CENPR
Centromere protein R

1

1

Small-scale

0.437

High

574569

SEC62
Translocation protein SEC62

1

1

High-throughput

0.437

High

574580

FBX6
F-box only protein 6

1

7

High-throughput

0.437

High

574568

VPS35
Vacuolar protein sorting-associated protein 35

1

0

Small-scale

0.426

High

574557

PATE1
Prostate and testis expressed protein 1

1

0

High-throughput

0.279

Low

574589

INSL5
Insulin-like peptide INSL5

1

0

High-throughput

0.279

Low

574545

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.249

Low

574553

CUL9
Cullin-9

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024