Interactor 1: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: NEB2 (Q6R891)
Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)
Gene: Ppp1r9b

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.918

The method score is based on:

Property Details
Experiments 28671696, 30562941, 20124353, 28634551, 36417873
Identification Methods affinity chromatography technology, pull down, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Guanylate_kin~PDZ, PDZ~PDZ, PDZ~PDZ_5
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0014069 - postsynaptic density
GO:0019900 - kinase binding
GO:0030425 - dendrite
and 2 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 724
Mm

1 817
+ Mm
+ Mm
+ Mm
+ Rn
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm
+ Mm
+ Rn
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024