Interactor 1: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: SHAN2 (Q80Z38)
SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin-binding protein 1) (CortBP1)
Gene: Shank2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 27507650, 28671696, 36417873
Identification Methods affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Guanylate_kin~SH3_2, PDZ~PDZ_6, PDZ~SAM_1, PDZ~SH3_2, SH3_1~SH3_2
Common GO terms GO:0005886 - plasma membrane
GO:0014069 - postsynaptic density
GO:0035176 - social behavior
GO:0035255 - ionotropic glutamate receptor binding
GO:0043005 - neuron projection
and 5 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 724
Mm

1 1476
+ Hs
+ Mm
+ Mm
+ Mm
+ Mm
+ Mm
+ Hs
+ Rn
+ Mm
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+ Mm
+ Mm
+ Mm
+ Ce
+ Hs
+ Rn

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Last updated: 15 Jul 2024