HitPredict

Interactor 1: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: ARC (Q9WV31)
Activity-regulated cytoskeleton-associated protein (mArc) (Activity-regulated gene 3.1 protein) (ARC/ARG3.1) (Arg3.1)
Gene: ARC

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 0.60 0.733

The method score is based on:

Property Details
Experiments 28804447, 27507650, 28671696, 36604605, 23424281, 19455133
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0030425 - dendrite
GO:0043197 - dendritic spine
GO:0048168 - regulation of neuronal synaptic plasticity
and 2 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 724
Mm

1 396
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024