Protein: CNOT2
CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2)

Gene: CNOT2
Organism: Homo sapiens
Interactions: 174
UniProt ID: Q9NZN8

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000932 - P-body
GO:0001222 - transcription corepressor binding
GO:0001829 - trophectodermal cell differentiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

257420

CNOT3
CCR4-NOT transcription complex subunit 3

10

15

Small-scale

0.975

High

61486

CNOT1
CCR4-NOT transcription complex subunit 1

7

6

Small-scale

0.961

High

1349343

CNOT7
CCR4-NOT transcription complex subunit 7

6

9

High-throughput

0.730

High

1349345

CNO11
CCR4-NOT transcription complex subunit 11

5

1

High-throughput

0.718

High

1297135

CNO6L
CCR4-NOT transcription complex subunit 6-like

5

10

Small-scale

0.716

High

1334105

CNO10
CCR4-NOT transcription complex subunit 10

5

1

High-throughput

0.714

High

1349340

CNOT8
CCR4-NOT transcription complex subunit 8

4

9

Small-scale

0.691

High

1267887

CNOT9
CCR4-NOT transcription complex subunit 9

4

7

High-throughput

0.686

High

1318952

TB182
182 kDa tankyrase-1-binding protein

4

7

Small-scale

0.683

High

1349347

CNOT6
CCR4-NOT transcription complex subunit 6

4

10

Small-scale

0.683

High

1136333

RC3H1
Roquin-1

4

5

Small-scale

0.676

High

813186

CAZA2
F-actin-capping protein subunit alpha-2

3

3

High-throughput

0.667

High

1335757

GPBL1
Vasculin-like protein 1

3

1

High-throughput

0.667

High

841402

TOB1
Protein Tob1

3

3

Small-scale

0.662

High

1336203

TNR6C
Trinucleotide repeat-containing gene 6C protein

3

13

Small-scale

0.660

High

1335209

RC3H2
Roquin-2

3

10

Small-scale

0.640

High

258875

GA45B
Growth arrest and DNA damage-inducible protein GADD45 beta

2

1

High-throughput

0.628

High

888503

NANO2
Nanos homolog 2

2

7

High-throughput

0.628

High

1050823

FHL2
Four and a half LIM domains protein 2

2

1

High-throughput

0.628

High

1233554

MINK1
Misshapen-like kinase 1

2

2

High-throughput

0.628

High

1349339

NLK
Serine/threonine-protein kinase NLK

2

1

High-throughput

0.628

High

317685

CNOT4
CCR4-NOT transcription complex subunit 4

2

3

Small-scale

0.624

High

163392

XPO1
Exportin-1

2

2

High-throughput

0.611

High

813796

CAPZB
F-actin-capping protein subunit beta

2

1

High-throughput

0.611

High

1266853

TM131
Transmembrane protein 131

2

7

High-throughput

0.611

High

1349338

WRP73
WD repeat-containing protein WRAP73

2

1

High-throughput

0.611

High

448893

MMP7
Matrilysin

3

1

High-throughput

0.609

High

1232873

RIBC1
RIB43A-like with coiled-coils protein 1

3

1

High-throughput

0.609

High

1139881

OBI1
ORC ubiquitin ligase 1

3

1

Small-scale

0.606

High

703450

CSTF2
Cleavage stimulation factor subunit 2

2

3

High-throughput

0.606

High

929701

RACK1
Small ribosomal subunit protein RACK1

2

1

High-throughput

0.606

High

1027958

TBX2
T-box transcription factor TBX2

2

3

High-throughput

0.606

High

1080568

ZFHX3
Zinc finger homeobox protein 3

2

1

High-throughput

0.606

High

1254518

CCHCR
Coiled-coil alpha-helical rod protein 1

2

1

High-throughput

0.606

High

1286249

ARMC5
Armadillo repeat-containing protein 5

2

2

High-throughput

0.606

High

1349351

FBW1A
F-box/WD repeat-containing protein 1A

2

0

High-throughput

0.602

High

1242674

TNR6A
Trinucleotide repeat-containing gene 6A protein

2

11

Small-scale

0.601

High

1349344

AGO2
Protein argonaute-2

2

4

Small-scale

0.601

High

1349348

TNR6B
Trinucleotide repeat-containing gene 6B protein

2

9

Small-scale

0.601

High

1219253

Z3H7A
Zinc finger CCCH domain-containing protein 7A

2

2

High-throughput

0.584

High

253214

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.580

High

656537

PSB4
Proteasome subunit beta type-4

2

0

High-throughput

0.580

High

781470

BCL6
B-cell lymphoma 6 protein

2

0

High-throughput

0.580

High

1024230

CSN1
COP9 signalosome complex subunit 1

2

0

High-throughput

0.580

High

1235929

GCSAM
Germinal center-associated signaling and motility protein

2

0

High-throughput

0.580

High

1315242

TEKT3
Tektin-3

2

0

High-throughput

0.580

High

1331953

CFA68
Cilia- and flagella-associated protein 68

2

0

High-throughput

0.580

High

1335449

BEX1
Protein BEX1

2

0

High-throughput

0.580

High

1315785

TX13A
Testis-expressed protein 13A

2

1

High-throughput

0.574

High

370589

ESR1
Estrogen receptor

2

9

High-throughput

0.571

High

62101

EPAB2
Embryonic polyadenylate-binding protein 2

1

4

High-throughput

0.536

High

282252

SEGN
Secretagogin

1

1

High-throughput

0.536

High

792036

HD
Huntingtin

1

1

High-throughput

0.536

High

796192

MAGA9
Melanoma-associated antigen 9

1

3

High-throughput

0.536

High

857235

CAZA1
F-actin-capping protein subunit alpha-1

1

3

High-throughput

0.536

High

984669

CALD1
Caldesmon

1

3

High-throughput

0.536

High

1162698

LARP1
La-related protein 1

1

4

High-throughput

0.536

High

1251675

UHMK1
Serine/threonine-protein kinase Kist

1

2

High-throughput

0.536

High

1263566

PSPC1
Paraspeckle component 1

1

5

High-throughput

0.536

High

1264320

NANO1
Nanos homolog 1

1

7

High-throughput

0.536

High

1332701

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.536

High

1332976

WDR26
WD repeat-containing protein 26

1

2

High-throughput

0.536

High

1349350

UBP24
Ubiquitin carboxyl-terminal hydrolase 24

1

1

High-throughput

0.536

High

1082432

DDB1
DNA damage-binding protein 1

1

0

High-throughput

0.518

High

177393

HDAC3
Histone deacetylase 3

1

1

Small-scale

0.515

High

371474

KLKB1
Plasma kallikrein

1

0

High-throughput

0.513

High

658446

DPOD1
DNA polymerase delta catalytic subunit

1

0

High-throughput

0.513

High

671352

RL12
Large ribosomal subunit protein uL11

1

0

High-throughput

0.513

High

869985

CA2D1
Voltage-dependent calcium channel subunit alpha-2/delta-1

1

0

High-throughput

0.513

High

881046

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.513

High

908190

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

1160636

CNKR3
Connector enhancer of kinase suppressor of ras 3

1

0

High-throughput

0.513

High

1219069

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1270233

THRSP
Thyroid hormone-inducible hepatic protein

1

0

High-throughput

0.513

High

1272383

RENT1
Regulator of nonsense transcripts 1

1

0

High-throughput

0.513

High

1291067

DDX11
ATP-dependent DNA helicase DDX11

1

0

High-throughput

0.513

High

1295491

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.513

High

1349337

KANL3
KAT8 regulatory NSL complex subunit 3

1

0

High-throughput

0.513

High

1085252

PDK4
[Pyruvate dehydrogenase

1

1

High-throughput

0.489

High

1299563

FACOS
FANCD2 opposite strand protein

1

1

High-throughput

0.489

High

1349342

S18L2
SS18-like protein 2

1

1

High-throughput

0.489

High

1028212

GPS2
G protein pathway suppressor 2

1

0

Small-scale

0.486

High

261600

NCOR1
Nuclear receptor corepressor 1

1

5

Small-scale

0.481

High

1349356

NCOR2
Nuclear receptor corepressor 2

1

6

Small-scale

0.481

High

160815

AURKA
Aurora kinase A

1

1

High-throughput

0.479

High

165085

SC16A
Protein transport protein Sec16A

1

3

High-throughput

0.479

High

166326

GRRE1
Granule associated Rac and RHOG effector protein 1

1

1

High-throughput

0.479

High

257714

ANR17
Ankyrin repeat domain-containing protein 17

1

3

High-throughput

0.479

High

264425

GGYF1
GRB10-interacting GYF protein 1

1

5

High-throughput

0.479

High

504874

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

553921

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

570129

CEBPB
CCAAT/enhancer-binding protein beta

1

2

High-throughput

0.479

High

575607

EGR1
Early growth response protein 1

1

1

High-throughput

0.479

High

587730

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

4

High-throughput

0.479

High

640648

DDX6
Probable ATP-dependent RNA helicase DDX6

1

3

High-throughput

0.479

High

644341

TTP
mRNA decay activator protein ZFP36

1

5

High-throughput

0.479

High

668439

RBMS1
RNA-binding motif, single-stranded-interacting protein 1

1

4

High-throughput

0.479

High

681633

DNJA1
DnaJ homolog subfamily A member 1

1

1

High-throughput

0.479

High

717386

CTNB1
Catenin beta-1

1

1

High-throughput

0.479

High

721641

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

821066

PRC2A
Protein PRRC2A

1

10

High-throughput

0.479

High

844267

FXR2
RNA-binding protein FXR2

1

5

High-throughput

0.479

High

875373

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.479

High

893182

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

1026564

RFA4
Replication protein A 30 kDa subunit

1

2

High-throughput

0.479

High

1030523

G3BP1
Ras GTPase-activating protein-binding protein 1

1

4

High-throughput

0.479

High

1044209

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

3

High-throughput

0.479

High

1049909

UBP2L
Ubiquitin-associated protein 2-like

1

6

High-throughput

0.479

High

1056767

PUM1
Pumilio homolog 1

1

5

High-throughput

0.479

High

1074775

SSXT
Protein SSXT

1

5

High-throughput

0.479

High

1089577

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

6

High-throughput

0.479

High

1129606

SMAG2
Protein Smaug homolog 2

1

1

High-throughput

0.479

High

1134158

UBAP2
Ubiquitin-associated protein 2

1

7

High-throughput

0.479

High

1159105

CEP85
Centrosomal protein of 85 kDa

1

4

High-throughput

0.479

High

1168856

MEX3B
RNA-binding protein MEX3B

1

3

High-throughput

0.479

High

1192396

YTHD3
YTH domain-containing family protein 3

1

8

High-throughput

0.479

High

1198401

PATL1
Protein PAT1 homolog 1

1

9

High-throughput

0.479

High

1219862

ANKH1
Ankyrin repeat and KH domain-containing protein 1

1

3

High-throughput

0.479

High

1222326

RAVR1
Ribonucleoprotein PTB-binding 1

1

5

High-throughput

0.479

High

1234506

MACOI
Macoilin

1

1

High-throughput

0.479

High

1241043

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

1242148

LS14A
Protein LSM14 homolog A

1

4

High-throughput

0.479

High

1252134

PUM2
Pumilio homolog 2

1

5

High-throughput

0.479

High

1254008

ALMS1
Centrosome-associated protein ALMS1

1

3

High-throughput

0.479

High

1266703

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

3

High-throughput

0.479

High

1269787

ESR2
Estrogen receptor beta

1

9

High-throughput

0.479

High

1270479

HDAC2
Histone deacetylase 2

1

1

High-throughput

0.479

High

1294272

FUBP3
Far upstream element-binding protein 3

1

1

High-throughput

0.479

High

1317038

YTHD1
YTH domain-containing family protein 1

1

8

High-throughput

0.479

High

1317751

CPEB1
Cytoplasmic polyadenylation element-binding protein 1

1

5

High-throughput

0.479

High

1318809

UNK
RING finger protein unkempt homolog

1

5

High-throughput

0.479

High

1326352

DDX24
ATP-dependent RNA helicase DDX24

1

2

High-throughput

0.479

High

1333002

TDRD3
Tudor domain-containing protein 3

1

1

High-throughput

0.479

High

1334281

AGO3
Protein argonaute-3

1

4

High-throughput

0.479

High

1343090

AKIP1
A-kinase-interacting protein 1

1

1

High-throughput

0.479

High

1344405

4ET
Eukaryotic translation initiation factor 4E transporter

1

1

High-throughput

0.479

High

1347615

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

1

High-throughput

0.479

High

1349341

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1349346

AGO1
Protein argonaute-1

1

4

High-throughput

0.479

High

1349349

SMG5
Nonsense-mediated mRNA decay factor SMG5

1

3

High-throughput

0.479

High

1349352

R3HD2
R3H domain-containing protein 2

1

7

High-throughput

0.479

High

1349353

SGT1
Protein SGT1 homolog

1

1

High-throughput

0.479

High

1349354

PRC2C
Protein PRRC2C

1

10

High-throughput

0.479

High

1349355

YTHD2
YTH domain-containing family protein 2

1

8

High-throughput

0.479

High

94680

F2Z2M7
Polypeptide N-acetylgalactosaminyltransferase 10

1

1

High-throughput

0.470

High

237332

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

0

High-throughput

0.458

High

328980

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.458

High

413117

AGAL
Alpha-galactosidase A

1

0

High-throughput

0.458

High

738420

BMR1A
Bone morphogenetic protein receptor type-1A

1

0

High-throughput

0.458

High

780227

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

919289

RAN
GTP-binding nuclear protein Ran

1

0

High-throughput

0.458

High

1036955

SQSTM
Sequestosome-1

1

0

Small-scale

0.458

High

1076357

JHD2C
Probable JmjC domain-containing histone demethylation protein 2C

1

0

High-throughput

0.458

High

1200243

N4BP2
NEDD4-binding protein 2

1

0

High-throughput

0.458

High

1244733

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

1283896

TTC17
Tetratricopeptide repeat protein 17

1

0

High-throughput

0.458

High

1336253

Q9HCK3
KIAA1569 protein

1

0

High-throughput

0.458

High

1344779

DISC1
Disrupted in schizophrenia 1 protein

1

1

High-throughput

0.457

High

108839

H0YCH8
A-kinase interacting protein 1

1

1

High-throughput

0.445

High

1197908

GLT10
Polypeptide N-acetylgalactosaminyltransferase 10

1

1

High-throughput

0.439

High

1127714

PRC2B
Protein PRRC2B

1

8

High-throughput

0.437

High

1242056

RN214
RING finger protein 214

1

1

High-throughput

0.437

High

1286549

ENTR1
Endosome-associated-trafficking regulator 1

1

1

High-throughput

0.437

High

102438

G3V529
ATP-dependent RNA helicase

1

2

High-throughput

0.407

High

474649

PRR35
Proline-rich protein 35

2

0

High-throughput

0.316

High

1327087

MFR1L
Mitochondrial fission regulator 1-like

2

0

High-throughput

0.316

High

1328797

CMIP1
Ciliary microtubule inner protein 1

2

0

High-throughput

0.316

High

173134

RT12
Small ribosomal subunit protein uS12m

1

0

High-throughput

0.279

Low

1335651

TM165
Putative divalent cation/proton antiporter TMEM165

1

0

High-throughput

0.279

Low

940658

F193A
Protein FAM193A

1

0

High-throughput

0.249

Low

1268562

K0232
Uncharacterized protein KIAA0232

1

0

High-throughput

0.249

Low

1330063

CPVL
Probable serine carboxypeptidase CPVL

1

0

High-throughput

0.249

Low

1332424

WDCP
WD repeat and coiled-coil-containing protein

1

0

High-throughput

0.249

Low

886353

DSCR9
Down syndrome critical region protein 9

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024