Protein: KLC1
Kinesin light chain 1 (KLC 1)

Gene: KLC1
Organism: Homo sapiens
Interactions: 152
UniProt ID: Q07866

Gene Ontology (top 5):
GO:0003774 - cytoskeletal motor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005871 - kinesin complex
GO:0005874 - microtubule

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1060573

KLC2
Kinesin light chain 2

6

16

High-throughput

0.949

High

1060578

KLC4
Kinesin light chain 4

5

16

High-throughput

0.930

High

1060529

KLC3
Kinesin light chain 3

5

15

High-throughput

0.919

High

1060590

JIP3
C-Jun-amino-terminal kinase-interacting protein 3

4

11

Small-scale

0.903

High

749903

KINH
Kinesin-1 heavy chain

11

20

Small-scale

0.756

High

729775

1433B
14-3-3 protein beta/alpha

7

20

High-throughput

0.747

High

1060510

KIF5A
Kinesin heavy chain isoform 5A

6

20

Small-scale

0.732

High

966234

1433G
14-3-3 protein gamma

5

20

High-throughput

0.720

High

990139

1433Z
14-3-3 protein zeta/delta

5

20

High-throughput

0.718

High

690939

1433T
14-3-3 protein theta

5

20

High-throughput

0.716

High

1049228

1433F
14-3-3 protein eta

5

20

High-throughput

0.716

High

244152

KIF5C
Kinesin heavy chain isoform 5C

4

20

Small-scale

0.691

High

1060511

BNIP2
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2

3

4

High-throughput

0.675

High

171806

AZIN1
Antizyme inhibitor 1

3

2

High-throughput

0.667

High

244845

TRAK2
Trafficking kinesin-binding protein 2

3

19

High-throughput

0.667

High

971437

1433E
14-3-3 protein epsilon

3

8

High-throughput

0.667

High

1060520

TRIP6
Thyroid receptor-interacting protein 6

3

3

High-throughput

0.667

High

421985

A4
Amyloid-beta precursor protein

3

3

Small-scale

0.656

High

323986

CSTN1
Calsyntenin-1

3

10

Small-scale

0.650

High

333326

SNAPN
SNARE-associated protein Snapin

3

0

High-throughput

0.634

High

252857

EXOC3
Exocyst complex component 3

2

1

High-throughput

0.628

High

1060527

RHG17
Rho GTPase-activating protein 17

2

2

High-throughput

0.628

High

1060547

KIF2B
Kinesin-like protein KIF2B

2

9

High-throughput

0.628

High

1060575

RABE2
Rab GTPase-binding effector protein 2

2

2

High-throughput

0.628

High

537036

HSP7C
Heat shock cognate 71 kDa protein

1

7

High-throughput

0.618

High

1060508

KLC1
Kinesin light chain 1

1

15

High-throughput

0.618

High

1060516

CUL3
Cullin-3

1

6

High-throughput

0.618

High

1060587

ANC2
Anaphase-promoting complex subunit 2

1

10

High-throughput

0.618

High

1060561

DTBP1
Dysbindin

2

2

High-throughput

0.611

High

1060544

SYNE4
Nesprin-4

3

8

High-throughput

0.609

High

1060595

KPTN
KICSTOR complex protein kaptin

3

2

High-throughput

0.609

High

1060541

ATCAY
Caytaxin

2

4

High-throughput

0.606

High

1060596

TACC3
Transforming acidic coiled-coil-containing protein 3

2

4

High-throughput

0.606

High

1060552

TP4AP
Short transient receptor potential channel 4-associated protein

2

0

High-throughput

0.602

High

241492

PRKN
E3 ubiquitin-protein ligase parkin

2

12

High-throughput

0.584

High

1060591

JIP1
C-Jun-amino-terminal kinase-interacting protein 1

2

6

Small-scale

0.584

High

1060525

AP1AR
AP-1 complex-associated regulatory protein

2

0

High-throughput

0.580

High

410796

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

4

High-throughput

0.576

High

553745

MYCL
Protein L-Myc

2

6

High-throughput

0.574

High

1060593

COG6
Conserved oligomeric Golgi complex subunit 6

2

2

High-throughput

0.574

High

1060519

K1H1
Keratin, type I cuticular Ha1

1

17

High-throughput

0.573

High

289984

OFD1
Centriole and centriolar satellite protein OFD1

2

1

High-throughput

0.571

High

529693

TAU
Microtubule-associated protein tau

2

8

High-throughput

0.552

High

1060521

EZH2
Histone-lysine N-methyltransferase EZH2

2

8

High-throughput

0.549

High

415525

HSPB1
Heat shock protein beta-1

1

2

High-throughput

0.541

High

771067

PE2R4
Prostaglandin E2 receptor EP4 subtype

1

1

High-throughput

0.541

High

1060530

LRSM1
E3 ubiquitin-protein ligase LRSAM1

1

2

High-throughput

0.541

High

1060556

TSC1
Hamartin

1

3

High-throughput

0.541

High

549573

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

3

High-throughput

0.536

High

877095

KC1D
Casein kinase I isoform delta

1

3

High-throughput

0.536

High

938555

PSA
Puromycin-sensitive aminopeptidase

1

1

High-throughput

0.536

High

1060517

NOLC1
Nucleolar and coiled-body phosphoprotein 1

1

4

High-throughput

0.536

High

1060531

RFIP1
Rab11 family-interacting protein 1

1

2

High-throughput

0.536

High

1060558

SPSB4
SPRY domain-containing SOCS box protein 4

1

11

High-throughput

0.536

High

1060564

ODAD1
Outer dynein arm-docking complex subunit 1

1

2

High-throughput

0.523

High

458386

ADRB2
Beta-2 adrenergic receptor

1

0

High-throughput

0.518

High

730538

1433S
14-3-3 protein sigma

1

20

High-throughput

0.515

High

621631

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.513

High

1060548

AVL9
Late secretory pathway protein AVL9 homolog

1

0

High-throughput

0.513

High

1060570

CEP44
Centrosomal protein of 44 kDa

1

0

High-throughput

0.513

High

1060522

MK06
Mitogen-activated protein kinase 6

1

2

High-throughput

0.508

High

936036

PAR2
Proteinase-activated receptor 2

1

1

High-throughput

0.494

High

648352

USF1
Upstream stimulatory factor 1

1

7

High-throughput

0.489

High

706108

S10A2
Protein S100-A2

1

9

High-throughput

0.489

High

889405

CLK1
Dual specificity protein kinase CLK1

1

6

High-throughput

0.489

High

1060534

RFIP2
Rab11 family-interacting protein 2

1

5

High-throughput

0.489

High

1060537

TLK2
Serine/threonine-protein kinase tousled-like 2

1

2

High-throughput

0.489

High

1060562

ZN503
Zinc finger protein 503

1

1

High-throughput

0.489

High

1060569

DPY30
Protein dpy-30 homolog

1

1

High-throughput

0.489

High

1060518

PCM1
Pericentriolar material 1 protein

1

1

High-throughput

0.481

High

341930

CEP43
Centrosomal protein 43

1

3

High-throughput

0.479

High

375450

RASK
GTPase KRas

1

6

High-throughput

0.479

High

606682

CEBPB
CCAAT/enhancer-binding protein beta

1

3

High-throughput

0.479

High

693296

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

2

High-throughput

0.479

High

710196

EPHA2
Ephrin type-A receptor 2

1

6

High-throughput

0.479

High

710817

EPHB2
Ephrin type-B receptor 2

1

3

High-throughput

0.479

High

830618

CCNF
Cyclin-F

1

5

High-throughput

0.479

High

931942

EPHB4
Ephrin type-B receptor 4

1

2

High-throughput

0.479

High

956711

RAB10
Ras-related protein Rab-10

1

2

Small-scale

0.479

High

959320

RAP1B
Ras-related protein Rap-1b

1

7

High-throughput

0.479

High

1060509

EP300
Histone acetyltransferase p300

1

4

High-throughput

0.479

High

1060515

HDAC1
Histone deacetylase 1

1

5

High-throughput

0.479

High

1060523

ARH
Low density lipoprotein receptor adapter protein 1

1

5

Small-scale

0.479

High

1060532

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

1060538

ZN598
E3 ubiquitin-protein ligase ZNF598

1

1

High-throughput

0.479

High

1060539

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.479

High

1060543

LMTK2
Serine/threonine-protein kinase LMTK2

1

13

High-throughput

0.479

High

1060545

RUSC2
AP-4 complex accessory subunit RUSC2

1

3

Small-scale

0.479

High

1060551

CC110
Coiled-coil domain-containing protein 110

1

2

High-throughput

0.479

High

1060553

RFFL
E3 ubiquitin-protein ligase rififylin

1

2

Small-scale

0.479

High

1060554

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

2

High-throughput

0.479

High

1060555

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

4

High-throughput

0.479

High

1060557

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

1

Small-scale

0.479

High

1060566

SORT
Sortilin

1

1

High-throughput

0.479

High

1060567

AASD1
Alanyl-tRNA editing protein Aarsd1

1

2

High-throughput

0.479

High

1060568

RUSC1
AP-4 complex accessory subunit RUSC1

1

3

Small-scale

0.479

High

1060571

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

1

High-throughput

0.479

High

1060572

WWTR1
WW domain-containing transcription regulator protein 1

1

7

High-throughput

0.479

High

1060581

RFOX1
RNA binding protein fox-1 homolog 1

1

8

High-throughput

0.479

High

1060584

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

1060585

AAKG3
5'-AMP-activated protein kinase subunit gamma-3

1

5

Small-scale

0.479

High

1060586

HOOK1
Protein Hook homolog 1

1

5

High-throughput

0.479

High

1060594

CBY1
Protein chibby homolog 1

1

2

High-throughput

0.479

High

418087

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

957342

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

992150

SKP1
S-phase kinase-associated protein 1

1

0

Small-scale

0.458

High

1060528

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1060580

BSDC1
BSD domain-containing protein 1

1

0

Small-scale

0.458

High

1060577

DISC1
Disrupted in schizophrenia 1 protein

1

1

High-throughput

0.457

High

62492

S35F4
Solute carrier family 35 member F4

1

1

High-throughput

0.445

High

142329

PEX7
Peroxisomal targeting signal 2 receptor

1

9

High-throughput

0.445

High

211306

RFOX2
RNA binding protein fox-1 homolog 2

1

8

High-throughput

0.445

High

934520

TERA
Transitional endoplasmic reticulum ATPase

1

4

High-throughput

0.445

High

943923

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

4

High-throughput

0.445

High

1060526

CP135
Centrosomal protein of 135 kDa

1

2

High-throughput

0.445

High

1060565

CEP63
Centrosomal protein of 63 kDa

1

2

High-throughput

0.445

High

1060579

DDX28
Probable ATP-dependent RNA helicase DDX28

1

5

High-throughput

0.445

High

1060546

NIN
Ninein

1

8

High-throughput

0.439

High

105813

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

246553

KDM1A
Lysine-specific histone demethylase 1A

1

4

High-throughput

0.437

High

411800

NTRK1
High affinity nerve growth factor receptor

1

10

High-throughput

0.437

High

588540

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.437

High

695291

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.437

High

717070

ECHM
Enoyl-CoA hydratase, mitochondrial

1

1

High-throughput

0.437

High

768032

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

1053451

FHI1A
FHF complex subunit HOOK-interacting protein 1A

1

10

High-throughput

0.437

High

1060512

CAF1A
Chromatin assembly factor 1 subunit A

1

1

High-throughput

0.437

High

1060513

TIF1B
Transcription intermediary factor 1-beta

1

2

High-throughput

0.437

High

1060524

FHI2A
FHF complex subunit HOOK interacting protein 2A

1

10

High-throughput

0.437

High

1060535

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

3

High-throughput

0.437

High

1060540

FHI2B
FHF complex subunit HOOK-interacting protein 2B

1

10

High-throughput

0.437

High

1060560

PF21A
PHD finger protein 21A

1

5

High-throughput

0.437

High

1060574

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

4

High-throughput

0.437

High

1060576

DJC18
DnaJ homolog subfamily C member 18

1

5

High-throughput

0.437

High

1060588

RCOR1
REST corepressor 1

1

2

High-throughput

0.437

High

1060592

DJC16
DnaJ homolog subfamily C member 16

1

9

High-throughput

0.437

High

1060559

P33MX
Putative monooxygenase p33MONOX

1

0

High-throughput

0.426

High

1060589

KDIS
Kinase D-interacting substrate of 220 kDa

1

0

High-throughput

0.426

High

791331

SYUA
Alpha-synuclein

1

2

Small-scale

0.408

High

330137

VENTX
Homeobox protein VENTX

1

3

High-throughput

0.407

High

1060533

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

5

High-throughput

0.407

High

1060583

S53A1
Solute carrier family 53 member 1

1

2

High-throughput

0.407

High

297586

PIAS1
E3 SUMO-protein ligase PIAS1

1

0

High-throughput

0.279

Low

1060542

CCD83
Coiled-coil domain-containing protein 83

1

0

High-throughput

0.279

Low

1060582

ORC3
Origin recognition complex subunit 3

1

0

High-throughput

0.279

Low

1060536

RIC3
Protein RIC-3

1

0

Small-scale

0.249

Low

1060549

MINY2
Ubiquitin carboxyl-terminal hydrolase MINDY-2

1

0

Small-scale

0.249

Low

1060550

RASF8
Ras association domain-containing protein 8

1

0

Small-scale

0.249

Low

1060514

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.232

Low

1060563

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.232

Low

1060597

ICOS
Inducible T-cell costimulator

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025