HitPredict

Interactor 1: TGFR2 (Q62312)
TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II)
Gene: Tgfbr2

Interactor 2: IRAK2 (Q8CFA1)
Interleukin-1 receptor-associated kinase-like 2 (IRAK-2) (mu-IRAK-2)
Gene: IRAK2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24319055
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~Pkinase
Common GO terms	GO:0005524 - ATP binding GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 567 Mm			1 622
+	At
		1247616 NIK2_ARATH (19-567): 4.73e-161: 475: 15.37		BAK1_ARATH (2-547): 1.1e-156: 465: 18.13
+	At
		1278198 BAK1_ARATH (4-555): 3.92e-159: 469: 14.31		BAK1_ARATH (2-547): 1.1e-156: 465: 18.13
+	At
		1013317 BAK1_ARATH (4-555): 3.92e-159: 469: 14.31		Y2239_ARATH (3-581): 5.99e-152: 454: 16.39
+	At
		1247614 NIK2_ARATH (19-567): 4.73e-161: 475: 15.37		Y4052_ARATH (3-581): 1.17e-149: 448: 16.03
+	At
		1277299 BAK1_ARATH (4-555): 3.92e-159: 469: 14.31		SERK1_ARATH (2-532): 2.17e-151: 452: 16.96
+	At
		1278214 BAK1_ARATH (4-555): 3.92e-159: 469: 14.31		NIK1_ARATH (3-544): 2.3e-151: 452: 15.17
+	At
		1258181 BAK1_ARATH (4-555): 3.92e-159: 469: 14.31		Y4052_ARATH (3-581): 1.17e-149: 448: 16.03
+	At
		1278231 BAK1_ARATH (4-555): 3.92e-159: 469: 14.31		SERK4_ARATH (2-519): 8.49e-149: 445: 17.16
+	At
		84522 NIK2_ARATH (19-567): 4.73e-161: 475: 15.37		Y4245_ARATH (21-527): 3.42e-142: 437: 17.85
+	At
		85020 BAK1_ARATH (4-555): 3.92e-159: 469: 14.31		Y5457_ARATH (4-521): 1.34e-145: 437: 17.57
+	At
		286290 NIK2_ARATH (19-567): 4.73e-161: 475: 15.37		Y2899_ARATH (13-527): 1.25e-138: 427: 17.39
+	At
		84275 NIK2_ARATH (19-567): 4.73e-161: 475: 15.37		C0LGM1_ARATH (26-554): 6.01e-138: 427: 15.75
+	At
		1275725 BAK1_ARATH (4-555): 3.92e-159: 469: 14.31		NIK3_ARATH (3-536): 1.56e-143: 432: 16.19
+	At
		1228433 BAK1_ARATH (4-555): 3.92e-159: 469: 14.31		SERK5_ARATH (2-519): 3.31e-143: 430: 16.79
+	At
		1163620 BAK1_ARATH (4-555): 3.92e-159: 469: 14.31		SRF8_ARATH (204-418): 1.13e-23: 107: 34.55
+	At
		1278233 BAK1_ARATH (4-555): 3.92e-159: 469: 14.31		Q9SNA0_ARATH (178-424): 2.85e-22: 103: 31.08
+	At
		1278202 BAK1_ARATH (4-555): 3.92e-159: 469: 14.31		SRF6_ARATH (189-418): 4.4e-22: 102: 32.20
+	At
		186969 BAK1_ARATH (4-555): 3.92e-159: 469: 14.31		BRI1_ARATH (4-141): 1.22e-11: 70.1: 9.40
+	At
		1278216 BAK1_ARATH (4-555): 3.92e-159: 469: 14.31		BRL3_ARATH (4-80): 8.82e-11: 67.4: 12.79