HitPredict

Interactor 1: SRBS1 (Q62417)
Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)
Gene: Sorbs1

Interactor 2: DLGP1 (Q9D415)
Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (PSD-95/SAP90-binding protein 1) (SAP90/PSD-95-associated protein 1) (SAPAP1)
Gene: Dlgap1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	27507650, 28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045202 - synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1290 Mm			1 992
+	Rn
		192741 SRBS2_RAT (71-1288): 3.86e-150: 486: 28.23		DLGP1_RAT (1-992): 0: 1344: 98.49
+	Mm
		1113254 SRBS2_MOUSE (71-1288): 3.66e-142: 464: 28.18		DLGP1_MOUSE (1-992): 0: 1344: 100.00
+	Hs
		145930 SRBS2_HUMAN (133-1288): 2.01e-124: 414: 25.94		DLGP1_HUMAN (1-992): 0: 1324: 94.46
+	Mm
		82778 B9EKJ1_MOUSE (196-1177): 3.28e-90: 325: 12.41		DLGP1_MOUSE (1-992): 0: 1344: 100.00
+	Mm
		561174 SPTN1_MOUSE (196-1177): 6.53e-90: 323: 12.41		DLGP1_MOUSE (1-992): 0: 1344: 100.00
+	Hs
		299006 SRBS2_HUMAN (133-1288): 2.01e-124: 414: 25.94		DLGP4_HUMAN (1-992): 0: 1071: 46.37
+	Hs
		145955 ITSN2_HUMAN (474-1288): 1.49e-32: 140: 10.57		DLGP1_HUMAN (1-992): 0: 1324: 94.46
+	Mm
		1246939 SH3K1_MOUSE (1103-1232): 2.04e-09: 64.1: 17.27		DLGP1_MOUSE (1-992): 0: 1344: 100.00
+	Hs
		145937 PLCG1_HUMAN (1175-1288): 7.56e-15: 82: 22.81		DLGP1_HUMAN (1-992): 0: 1324: 94.46
+	Hs
		145943 GRB2_HUMAN (1233-1286): 2.84e-15: 78.4: 32.73		DLGP1_HUMAN (1-992): 0: 1324: 94.46
+	Hs
		145950 ITSN1_HUMAN (822-1288): 3.63e-10: 67: 11.75		DLGP1_HUMAN (1-992): 0: 1324: 94.46
+	Hs
		235607 VINEX_HUMAN (812-1288): 3.2e-43: 170: 31.19		DLGP2_HUMAN (1-992): 0: 1081: 51.69
+	Hs
		4614 VINEX_HUMAN (812-1288): 3.2e-43: 170: 31.19		A0A1B0GTN4_HUMAN (1-992): 0: 1080: 51.69
+	Hs
		209192 NCK2_HUMAN (973-1208): 5.89e-20: 95.7: 20.97		DLGP4_HUMAN (1-992): 0: 1071: 46.37
+	Hs
		581066 PLCG1_HUMAN (1175-1288): 7.56e-15: 82: 22.81		DLGP2_HUMAN (1-992): 0: 1081: 51.69
+	Hs
		4616 PLCG1_HUMAN (1175-1288): 7.56e-15: 82: 22.81		A0A1B0GTN4_HUMAN (1-992): 0: 1080: 51.69
+	Hs
		924914 GRB2_HUMAN (1233-1286): 2.84e-15: 78.4: 32.73		DLGP2_HUMAN (1-992): 0: 1081: 51.69
+	Hs
		924968 GRB2_HUMAN (1233-1286): 2.84e-15: 78.4: 32.73		DLGP4_HUMAN (1-992): 0: 1071: 46.37
+	Hs
		327226 PLCG1_HUMAN (1175-1288): 7.56e-15: 82: 22.81		DLGP3_HUMAN (1-992): 0: 986: 37.16
+	Hs
		327232 GRB2_HUMAN (1233-1286): 2.84e-15: 78.4: 32.73		DLGP3_HUMAN (1-992): 0: 986: 37.16