Protein: LNX1
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb protein X 1) (Ligand of Numb-binding protein 1) (Numb-binding protein 1) (RING-type E3 ubiquitin transferase LNX)

Gene: LNX1
Organism: Mus musculus
Interactions: 87
UniProt ID: O70263

Gene Ontology (top 5):
GO:0004842 - ubiquitin-protein transferase activity
GO:0005737 - cytoplasm
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0008270 - zinc ion binding
GO:0016567 - protein ubiquitination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

266822

NUMB
Protein numb homolog

1

20

Small-scale

0.724

High

401

A0A087WPM2
Protein tyrosine phosphatase, receptor type, f polypeptide

1

16

High-throughput

0.618

High

74692

B2RXW8
Ppfia1 protein

1

16

High-throughput

0.618

High

266749

LNX1
E3 ubiquitin-protein ligase LNX

1

17

Small-scale

0.618

High

266753

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

1

5

High-throughput

0.618

High

266765

PP2BA
Protein phosphatase 3 catalytic subunit alpha

1

20

High-throughput

0.618

High

266797

TRIM9
E3 ubiquitin-protein ligase TRIM9

1

17

High-throughput

0.618

High

266815

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit [Cleaved into: cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed]

1

9

High-throughput

0.618

High

266788

IGSF5
Immunoglobulin superfamily member 5

1

6

Small-scale

0.561

High

266760

LIPA3
Liprin-alpha-3

1

16

High-throughput

0.553

High

266780

KAZRN
Kazrin

1

14

High-throughput

0.553

High

266795

LIPA2
Liprin-alpha-2

1

20

High-throughput

0.553

High

266798

LIPB1
Liprin-beta-1

1

15

High-throughput

0.553

High

266754

CAH1
Carbonic anhydrase 1

1

5

Small-scale

0.552

High

266771

CXAR
Coxsackievirus and adenovirus receptor homolog

1

20

Small-scale

0.506

High

59340

CAMP1
Calmodulin-regulated spectrin-associated protein 1

1

1

High-throughput

0.479

High

204893

CDK14
Cyclin-dependent kinase 14

1

5

High-throughput

0.479

High

266758

HS74L
Heat shock 70 kDa protein 4L

1

8

High-throughput

0.479

High

266761

1433G
14-3-3 protein gamma [Cleaved into: 14-3-3 protein gamma, N-terminally processed]

1

20

High-throughput

0.479

High

266762

LIS1
Platelet-activating factor acetylhydrolase IB subunit beta

1

2

High-throughput

0.479

High

266763

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.479

High

266764

KPCG
Protein kinase C gamma type

1

20

High-throughput

0.479

High

266767

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

Small-scale

0.479

High

266772

CTNB1
Catenin beta-1

1

20

High-throughput

0.479

High

266774

FCSD2
F-BAR and double SH3 domains protein 2

1

10

High-throughput

0.479

High

266776

CTNA2
Catenin alpha-2

1

7

High-throughput

0.479

High

266778

NDRG1
Protein NDRG1

1

2

High-throughput

0.479

High

266779

HECAM
Hepatic and glial cell adhesion molecule

1

11

High-throughput

0.479

High

266781

CARL1
F-actin-uncapping protein LRRC16A

1

1

High-throughput

0.479

High

266786

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

16

High-throughput

0.479

High

266787

CYFP1
Cytoplasmic FMR1-interacting protein 1

1

3

High-throughput

0.479

High

266790

C170B
Centrosomal protein of 170 kDa protein B

1

9

High-throughput

0.479

High

266794

ATLA1
Atlastin-1

1

1

High-throughput

0.479

High

266800

FERM2
Fermitin family homolog 2

1

2

High-throughput

0.479

High

266801

TBCE
Tubulin-specific chaperone E

1

5

High-throughput

0.479

High

266804

WASF1
Actin-binding protein WASF1

1

7

High-throughput

0.479

High

266805

MIOS
GATOR2 complex protein MIOS

1

1

High-throughput

0.479

High

266812

RB6I2
ELKS/Rab6-interacting/CAST family member 1

1

12

High-throughput

0.479

High

266814

DTNA
Dystrobrevin alpha

1

8

High-throughput

0.479

High

266818

SRCN1
SRC kinase signaling inhibitor 1

1

8

High-throughput

0.479

High

266819

ADDA
Alpha-adducin

1

5

High-throughput

0.479

High

266820

NDRG3
Protein NDRG3

1

2

High-throughput

0.479

High

266821

NDRG2
Protein NDRG2

1

2

High-throughput

0.479

High

266823

UN13B
Protein unc-13 homolog B

1

13

High-throughput

0.479

High

266803

SNP47
Synaptosomal-associated protein 47

1

0

High-throughput

0.458

High

73148

SCN7A
Sodium channel protein type 7 subunit alpha

1

5

Small-scale

0.457

High

86304

CTTB2
Cortactin-binding protein 2

1

12

High-throughput

0.437

High

205308

AP1B1
AP-1 complex subunit beta-1

1

4

High-throughput

0.437

High

205510

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

4

High-throughput

0.437

High

205671

CTND2
Catenin delta-2

1

20

High-throughput

0.437

High

266750

CLD1
Claudin-1

1

7

Small-scale

0.437

High

266751

K1C13
Keratin, type I cytoskeletal 13

1

10

High-throughput

0.437

High

266752

PFKAL
ATP-dependent 6-phosphofructokinase, liver type

1

3

High-throughput

0.437

High

266755

HS71B
Heat shock 70 kDa protein 1B

1

8

High-throughput

0.437

High

266756

SC6A1
Sodium- and chloride-dependent GABA transporter 1

1

20

High-throughput

0.437

High

266759

EAA1
Excitatory amino acid transporter 1

1

6

High-throughput

0.437

High

266766

1433T
14-3-3 protein theta

1

20

High-throughput

0.437

High

266768

LDB1
LIM domain-binding protein 1

1

1

High-throughput

0.437

High

266769

TCPB
T-complex protein 1 subunit beta

1

2

High-throughput

0.437

High

266770

NPTN
Neuroplastin

1

9

High-throughput

0.437

High

266773

Q3U2G2
Heat shock 70 kDa protein 4

1

8

High-throughput

0.437

High

266775

2A5G
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform

1

1

High-throughput

0.437

High

266777

K1C15
Keratin, type I cytoskeletal 15

1

11

High-throughput

0.437

High

266782

SPKAP
A-kinase anchor protein SPHKAP

1

2

High-throughput

0.437

High

266783

BCR
Breakpoint cluster region protein

1

20

High-throughput

0.437

High

266784

PHLB1
Pleckstrin homology-like domain family B member 1

1

20

High-throughput

0.437

High

266785

ERC2
ERC protein 2

1

19

High-throughput

0.437

High

266792

GSTM7
Glutathione S-transferase Mu 7

1

2

High-throughput

0.437

High

266793

EFTU
Elongation factor Tu, mitochondrial

1

4

High-throughput

0.437

High

266796

Q8C048
Calcium-transporting ATPase

1

14

High-throughput

0.437

High

266799

KLH11
Kelch-like protein 11

1

10

High-throughput

0.437

High

266802

IQEC1
IQ motif and SEC7 domain-containing protein 1

1

8

High-throughput

0.437

High

266806

Q91V89
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit

1

1

High-throughput

0.437

High

266807

Q91WH7
Sodium/potassium-transporting ATPase subunit alpha

1

5

High-throughput

0.437

High

266808

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.437

High

266809

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

20

High-throughput

0.437

High

266810

SRGP1
SLIT-ROBO Rho GTPase-activating protein 1

1

20

High-throughput

0.437

High

266811

VMA5A
von Willebrand factor A domain-containing protein 5A

1

1

High-throughput

0.437

High

266813

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.437

High

266817

NDEL1
Nuclear distribution protein nudE-like 1

1

5

High-throughput

0.437

High

266824

AT12A
Potassium-transporting ATPase alpha chain 2

1

5

High-throughput

0.437

High

237027

ENTP2
Ectonucleoside triphosphate diphosphohydrolase 2

1

0

High-throughput

0.249

Low

266757

SYWC
Tryptophan--tRNA ligase, cytoplasmic

1

0

High-throughput

0.249

Low

266789

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

266791

TCPR1
Tectonin beta-propeller repeat-containing protein 1

1

0

High-throughput

0.249

Low

266816

DGCR8
Microprocessor complex subunit DGCR8

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025