HitPredict

Interactor 1: UBC (Q63429)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related]
Gene: UBC

Interactor 2: CSN3 (Q68FW9)
COP9 signalosome complex subunit 3 (SGN3) (Signalosome subunit 3)
Gene: Cops3

Species: Rattus norvegicus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22871113
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 810 Rn			1 423
+	Rn
		897345 UBC_RAT (1-810): 0: 1000: 100.00		CSN2_RAT (21-393): 1.7e-87: 274: 11.97
+	Hs
		476573 UBC_HUMAN (1-533): 0: 662: 99.81		CSN3_HUMAN (1-423): 2.71e-143: 416: 99.76
+	Hs
		198528 UBC_HUMAN (1-533): 0: 662: 99.81		PSMD3_HUMAN (49-415): 1.12e-92: 290: 18.14
+	Hs
		475555 UBC_HUMAN (1-533): 0: 662: 99.81		CSN2_HUMAN (21-393): 1.7e-87: 274: 11.97
+	Hs
		121666 UBC_HUMAN (1-533): 0: 662: 99.81		PSD11_HUMAN (20-385): 1.16e-81: 258: 14.91
+	Hs
		476293 UBC_HUMAN (1-533): 0: 662: 99.81		CSN4_HUMAN (1-396): 2.03e-62: 208: 15.50
+	At
		1092162 UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22		PSD3B_ARATH (17-414): 2.45e-101: 311: 16.67
+	At
		1092148 UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22		PSD3A_ARATH (17-414): 1.24e-99: 307: 15.91
+	Sc
		477298 UBI4P_YEAST (457-801): 3.68e-132: 400: 90.73		RPN3_YEAST (115-416): 1.24e-66: 222: 18.69
+	At
		1092149 UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22		PSD11_ARATH (30-385): 5.27e-72: 233: 14.80
+	Sc
		477496 UBI4P_YEAST (457-801): 3.68e-132: 400: 90.73		RPN6_YEAST (113-393): 1.19e-14: 77.2: 13.89
+	Hs
		198601 RS27A_HUMAN (685-760): 5.08e-42: 152: 100.00		PSMD3_HUMAN (49-415): 1.12e-92: 290: 18.14
+	Mm
		476681 UBC_MOUSE (1-108): 6.19e-31: 132: 90.74		PSMD3_MOUSE (54-415): 5.08e-92: 289: 19.42
+	Hs
		121730 RS27A_HUMAN (685-760): 5.08e-42: 152: 100.00		PSD11_HUMAN (20-385): 1.16e-81: 258: 14.91
+	Mm
		476740 UBC_MOUSE (1-108): 6.19e-31: 132: 90.74		CSN2_MOUSE (21-393): 1.7e-87: 274: 11.97
+	Hs
		198523 ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69		PSMD3_HUMAN (49-415): 1.12e-92: 290: 18.14
+	Mm
		476877 UBC_MOUSE (1-108): 6.19e-31: 132: 90.74		PSD11_MOUSE (20-385): 1.3e-81: 258: 14.91
+	Hs
		121663 ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69		PSD11_HUMAN (20-385): 1.16e-81: 258: 14.91
+	Mm
		291853 UBC_MOUSE (1-108): 6.19e-31: 132: 90.74		CSN4_MOUSE (1-396): 1.34e-62: 209: 15.01